Osteoarthritis of the Knee
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: To Evaluate the Safety and Efficacy of TD0015 Pilulae in Patients with Knee Osteoarthritis [Phase 2]
A Phase 2 clinical trial is evaluating the safety and efficacy of TD0015 Pilulae for knee osteoarthritis, sponsored by Sao Thai Duong Joint …
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: A Phase 2, Open Label, Pharmacokinetic (PK) Study of TLC599 in Subjects With Osteoarthritis of the Knee [Phase 2]
Phase 2 open-label pharmacokinetic study of TLC599 in osteoarthritis of the knee completed; results pending release.
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: Efficacy and Safety of Sinovial®HL Single Injection in the Knee Osteoarthritis
Completed clinical trial assessing the efficacy and safety of Sinovial HL single-injection for knee osteoarthritis.
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Variations in Osteoarthritic Knee Laxity Between Individuals and Populations
This completed clinical trial investigates how knee laxity varies among individuals and populations in the context of knee osteoarthritis.
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Early Clinical and Radiological Outcomes of a Novel Robotic TKA System [NA]
Early clinical and radiological outcomes from a completed trial of a novel robotic total knee arthroplasty system.
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Cryoneurolysis for the Management of Chronic Pain in Patients With Knee Osteoarthritis [NA]
Completed clinical trial assessing cryoneurolysis for chronic pain in knee osteoarthritis; the update does not present efficacy results.
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: LEGION™ Primary Safety and Efficacy [NA]
A terminated LEGION study from Smith & Nephew reports primary safety and efficacy results for osteoarthritis of the knee; results have been …
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: In-vivo Wear Behaviour of AS Coated Versus Uncoated Columbus® Total Knee Prosthesis
A terminated clinical trial evaluated the in-vivo wear behavior of AS-coated versus uncoated Columbus Total Knee Prostheses.
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: Clinical Trial to Evaluate the Regeneration of Articular Cartilage Through Arthroscopy After MegaCarti® Application
This entry reports the completion of a clinical trial assessing articular cartilage regeneration in the knee after MegaCarti application del…
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Extended and Controlled Release Liposomal Formulated Dexamethasone for Chronic Knee OA Pain [Phase 3]
Phase 3 trial results for an extended-release liposomal dexamethasone formulation in knee osteoarthritis have been completed and results pos…
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Incidence of Tenderness Opposite to Adductor Canal in Patients Suffering From Osteoarthritis Knee Pain. A Cohort Study.
A completed cohort study from Cairo University examining the incidence of tenderness opposite the adductor canal in patients with knee osteo…
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: EXPAREL IPSA Block in Knee Arthroplasty [Phase 4]
Clinical trial update indicates EXPAREL is being studied for an IPSA block in knee arthroplasty in a Phase 4 study, with enrollment by invit…
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CLINICAL_TRIALS trial_result · 2024-09-26Clinical Trial Update: Erector Spinae Plane Block Vs. IPACK Block with Adductor Canal Block for Total Knee Arthroplasty [Phase 4]
A Phase 4 completed trial comparing Erector Spinae Plane Block versus IPACK Block with Adductor Canal Block for analgesia in total knee arth…
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: Orthosensor vs Conventional Total Knee Arthroplasty [NA]
A completed clinical trial comparing Orthosensor-assisted total knee arthroplasty to conventional total knee arthroplasty for osteoarthritis…
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: Exercise Program After Total Hip and Knee Replacement: a Randomized Controlled Trial [NA]
A completed randomized controlled trial evaluated an exercise program following total hip or knee replacement.
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: Late-initiated Blood Flow Restricted Rehabilitation Exercises After Total Knee Replacement [NA]
A clinical trial evaluating late-initiated blood flow restricted rehabilitation after total knee replacement was terminated, per an update f…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Intraosseous Morphine in Primary TKA [Phase 4]
Phase 4 trial results have been posted for intraosseous morphine used for pain control in primary total knee arthroplasty.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Senolytic Drugs Attenuate Osteoarthritis-Related Articular Cartilage Degeneration: A Clinical Trial [Phase 1, Phase 2]
A Phase 1/2 clinical trial of senolytic drugs for knee osteoarthritis has completed enrollment and posted results in 2024. The study investi…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Safety and Efficacy of the Oxford Cementless Partial Knee System [NA]
This completed trial checks safety and efficacy of the Oxford Cementless Partial Knee System by Zimmer Biomet in knee conditions. Results we…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Evaluation of Clinical and Radiographic Outcomes of Meniscal Lesion Treatment Using Collagen Scaffolds (CMI)
A completed clinical trial evaluating clinical and radiographic outcomes of treating meniscal lesions with collagen scaffolds in patients wi…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Impact of a POPOP on Preoperative Health, Eligibility, and Clinical & Patient-Reported Outcomes in TJA [NA]
This document reports a completed clinical trial from the University of Arkansas examining the impact of a POPOP on preoperative health, eli…
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: Euflexxa for the Treatment of Osteoarthritis [NA]
Completed clinical trial evaluating Euflexxa for knee osteoarthritis has posted results as of 2024-09-04.
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CLINICAL_TRIALS trial_result · 2024-08-30Clinical Trial Update: Adapting REhabilitation Delivery for Maximum Impact at Home [NA]
Completed University of Alberta trial evaluating home-based rehabilitation delivery for knee and hip osteoarthritis.
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CLINICAL_TRIALS trial_result · 2024-08-29Clinical Trial Update: Efficacy and Safety of MM-II for Treatment of Knee Pain in Subjects With Symptomatic Knee Osteoarthritis [Phase 2]
This clinical trial update reports efficacy and safety results for MM-II in treating knee pain due to symptomatic knee osteoarthritis in a P…
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Precision Application of Clostridium Butyricm of Clinical Research on Osteoarthritis [NA]
A completed clinical trial evaluating the precision application of Clostridium butyricum for knee osteoarthritis.