Osteoarthritis of the Knee
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Generate a Pharmacodynamic Model of Oxytocin for Peripheral Analgesic Effects [Phase 2]
Phase 2 trial update exploring a pharmacodynamic model of oxytocin for peripheral analgesia, conducted in knee osteoarthritis; the study was…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: A First-in-Human Study of XSTEM-OA in Patients With Knee Osteoarthritis [Phase 1, Phase 2]
A first-in-human study of XSTEM-OA for knee osteoarthritis in Phase 1/2 has completed.
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: Evaluate the Performance of JOURNEY II CR in TKA Populations
This update reports the results of the JOURNEY II CR total knee arthroplasty study in knee replacement patients; the trial was terminated an…
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: Pain Relief for OsteoArthritis Through Combined Treatment (PROACT) [NA]
The PROACT clinical trial, investigating combined treatment for pain relief in knee osteoarthritis, has completed and posted results on 2025…
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Functionally Aligned vs Mechanical Axis Aligned Total Knee Arthroplasty [NA]
This completed clinical trial compared functionally aligned versus mechanically aligned total knee arthroplasty in knee osteoarthritis; resu…
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Comparison of the Effectiveness of Conventional and Pulse Radiofrequency Therapy in Advanced Knee Osteoarthritis in Elderly Patients: An Observational Study
This clinical trial update reports an observational comparison of conventional and pulse radiofrequency therapy for advanced knee osteoarthr…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Evaluation of Treatment of Osteoarthritis of the Knee in the Form of Chondromalacia of the Articular Cartilage Treated in the Arthroscopic Technique With the Use of:Autogenous Transplantation of Fragmented Adipose Tissue,PRP GF,Mesenchymal Cells,Hyaluronic Acid-low Molecular Weight and Cross-linked [NA]
Clinical trial evaluating autologous adipose tissue transplantation, platelet-rich plasma with growth factors, mesenchymal cells, and hyalur…
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CLINICAL_TRIALS trial_result · 2025-08-05Clinical Trial Update: Exercise-induced Irisin in Individuals With Knee Osteoarthritis. [NA]
Completion of a clinical trial investigating exercise-induced irisin in individuals with knee osteoarthritis.
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CLINICAL_TRIALS trial_result · 2025-07-25Clinical Trial Update: A Clinical Study Evaluating the Dermal Safety of Soluble Denosumab Microneedle Patches [Phase 1]
Phase 1 trial evaluating the dermal safety of soluble denosumab delivered via microneedle patches; the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: Treatment and Duration Effect of Pentosan Polysulfate Sodium (PPS) in Participants With Knee Osteoarthritis Pain
A completed clinical trial evaluating the treatment effects and duration of Pentosan polysulfate sodium (PPS) for knee osteoarthritis pain.
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: COMPARISON OF THE EFFECT OF DISTAL ADDUCTOR CANAL BLOCK COMBINED WITH GENICULAR NERVE BLOCK OR PERIARTICULAR INJECTION ON POSTOPERATIVE QOR-15 IN TOTAL KNEE ARTHROPLASTIES [NA]
Completed clinical trial comparing distal adductor canal block with genicular nerve block versus periarticular injection for postoperative q…
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CLINICAL_TRIALS trial_result · 2025-07-16Clinical Trial Update: LIA vs. LIA + ACB-iPACK Block for Total Knee Arthroplasty [NA]
This clinical trial compares local infiltration analgesia (LIA) alone versus LIA plus adductor canal block with iPACK block (ACB-iPACK) for …
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: Strain Counterstrain and Muscle Energy Technique in Patients of Knee Osteoarthritis [NA]
This completed clinical trial evaluates strain-counterstrain and muscle-energy technique in patients with knee osteoarthritis. The record al…
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: The Effect of Whole-Body Vibration Treatment Before Total Knee Arthroplasty [NA]
A completed clinical trial from Gazi University assessing preoperative whole-body vibration therapy for knee osteoarthritis prior to total k…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Mako Functionally Aligned Total Knee Arthroplasty vs Mako Mechanically Aligned Total Knee Arthroplasty [NA]
A completed clinical trial comparing Mako functionally aligned total knee arthroplasty with Mako mechanically aligned total knee arthroplast…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Does Rehabilitation After Total Knee Arthroplasty Work? - Feasibility Trial [NA]
A completed feasibility trial from Copenhagen University Hospital evaluated rehabilitation after total knee arthroplasty to assess practical…
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CLINICAL_TRIALS trial_result · 2025-07-08Clinical Trial Update: Effects of OEP on Rehabilitation Outcomes on TKR Patients [NA]
A completed clinical trial evaluating the Effects of OEP on rehabilitation outcomes in patients undergoing total knee replacement.
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: Mulligan and Maitland Techniques in Post PRP Knee Osteoarthritis [NA]
A clinical trial evaluating Mulligan and Maitland manual techniques following PRP treatment for knee osteoarthritis has completed.
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Comparing Different Types of Physical Therapy for Treating People With a Meniscal Tear and Osteoarthritis [NA]
Completed clinical trial comparing different types of physical therapy for treating knee meniscal degeneration and osteoarthritis.
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: A 12-Week Home-Based Electrical Stimulation Program for Strength in Adults With Knee Osteoarthritis [NA]
A 12-week home-based electrical stimulation program for strengthening in adults with knee osteoarthritis has been terminated, with results p…
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CLINICAL_TRIALS trial_result · 2025-07-02Clinical Trial Update: Analgesic Effects of a Treatment With Cannabis Sativa Extract in Patients With Knee Osteoarthritis - CANOA (Cannabis for Osteoarthritis) [Phase 2]
A Phase 2 clinical trial evaluating Cannabis sativa extract for analgesic effects in knee osteoarthritis has completed. The update summarize…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Effects of Blood-flow Restricted Exercise Compared to Standard Rehabilitation in Patients With Knee Osteoarthritis [NA]
A completed trial comparing blood-flow restricted exercise to standard rehabilitation in knee osteoarthritis; results are reported in the Cl…
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: The Open Kinetic Chain and Closed Kinetic Chain Strengthening Exercises in Degenerative Meniscus Tears [NA]
This completed clinical trial from Istanbul University-Cerrahpasa evaluated open kinetic chain versus closed kinetic chain strengthening exe…
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: The Effect of Continuous Care Counseling Based on the Roy Adaptation Model on Comfort and Quality of Life in Patients Undergoing Total Knee Arthroplasty [NA]
This completed clinical trial evaluated whether continuous care counseling based on the Roy Adaptation Model improves comfort and quality of…
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CLINICAL_TRIALS trial_result · 2025-06-06Clinical Trial Update: A Prospective Study to Evaluate Robot Assisted Total Knee Replacement Outcomes [NA]
A terminated prospective trial evaluating robot-assisted total knee replacement outcomes has posted results in 2025.