Osteoarthritis of the Knee
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CLINICAL_TRIALS trial_result · 2012-10-05Clinical Trial Update: A Study Comparing Duloxetine Versus Placebo in Patients Taking a Nonsteroidal Anti-inflammatory Drug (NSAID) for Knee Pain Due to Osteoarthritis [Phase 3]
Phase 3 study comparing duloxetine to placebo in knee osteoarthritis patients using NSAIDs; the trial is completed and results were posted i…
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CLINICAL_TRIALS trial_result · 2012-08-27Clinical Trial Update: A Study Comparing the Effectiveness and Safety of Varying Dose Strengths (100, 200, 300 and 400 mg) of Extended-release Tramadol HCl With Placebo for the Treatment of Osteoarthritis(OA) of the Knee and/or Hip [Phase 3]
It summarizes a completed Phase 3 trial comparing multiple doses of extended-release tramadol hydrochloride with placebo for osteoarthritis …
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CLINICAL_TRIALS trial_result · 2012-07-12Clinical Trial Update: Evaluation of Clinical Endpoints of Two Diclofenac Sodium Gel 1% [Phase 3]
Phase 3 trial evaluating clinical endpoints for two diclofenac sodium 1% gel formulations in osteoarthritis of the knee. The study has compl…
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CLINICAL_TRIALS trial_result · 2012-07-10Clinical Trial Update: Impact of Noninvasive Targeted Pulsed Electromagnetic Field (tPEMF) on Opioid Use, Pain, and Joint Function Following Total Knee Arthroplasty [Phase 4]
Phase 4 trial evaluating noninvasive targeted pulsed electromagnetic field (tPEMF) to reduce opioid use and improve pain and knee function a…
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CLINICAL_TRIALS trial_result · 2012-06-29Clinical Trial Update: Outcome of Patients After Total Knee Replacement: A Comparison of Femoral Nerve Block and Epidural Anesthesia [NA]
Completed clinical trial comparing femoral nerve block versus epidural anesthesia for total knee replacement, reporting patient outcomes inc…
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CLINICAL_TRIALS trial_result · 2012-06-27Clinical Trial Update: Investigation of Specific Protein/Markers in Patients With Osteoarthritis of the Knee Having a Total Knee Replacement
A completed AstraZeneca-sponsored clinical trial investigated specific proteins/markers in patients with osteoarthritis of the knee undergoi…
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CLINICAL_TRIALS trial_result · 2012-06-21Clinical Trial Update: A Study Comparing the Effectiveness and Safety of Extended Release Tramadol Versus Placebo for the Treatment of Osteoarthritis (OA) of the Knee [Phase 3]
This document reports the completion of a Phase 3 study comparing extended-release tramadol to placebo for knee osteoarthritis, focusing on …
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CLINICAL_TRIALS trial_result · 2012-06-06Clinical Trial Update: A Double-blind, Randomized, Parallel Group, Fase III Comparative Study With Rose Hip Powder Powder and Placebo Given to Patients With Mild to Moderate Osteoarthritis in the Knee or/and Hip [Phase 3]
Phase III randomized trial comparing Rose Hip Powder to placebo in mild-to-moderate knee or hip osteoarthritis; the study has completed.
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CLINICAL_TRIALS trial_result · 2012-06-05Clinical Trial Update: Transdermal Ketoprofen to Treat Mild to Moderate Osteoarthritis (OA) Pain of the Knee [Phase 2]
A Phase 2 trial evaluated a transdermal ketoprofen patch for knee osteoarthritis and the study has completed.
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CLINICAL_TRIALS trial_result · 2012-06-04Clinical Trial Update: Investigation of 1.2% Sodium Hyaluronate for Treatment of Painful Chronic Osteoarthritis of the Knee [Phase 3]
Phase 3 trial of 1.2% sodium hyaluronate for painful chronic osteoarthritis of the knee completed with results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-05-28Clinical Trial Update: Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of AZD1386 in Patients With Osteoarthritis (OA) of the Knee [Phase 2]
Phase 2 trial evaluating AZD1386 in knee osteoarthritis was terminated, and results have been posted.
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CLINICAL_TRIALS trial_result · 2012-05-21Clinical Trial Update: Alignment Comparison Between TruMatch™ Personalized Solutions and Conventional Total Knee Replacement Instrumentation [NA]
A completed clinical trial comparing TruMatch personalized solutions with conventional total knee replacement instrumentation for osteoarthr…
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CLINICAL_TRIALS trial_result · 2012-05-21Clinical Trial Update: Nuclear Magnetic Resonance Therapy in Knee Osteoarthrosis [NA]
A clinical trial of Nuclear Magnetic Resonance Therapy for knee osteoarthritis has completed.
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CLINICAL_TRIALS trial_result · 2012-05-16Clinical Trial Update: A Study for Moderate Osteoarthritis of the Knee [Phase 1, Phase 2]
A Phase 1/2 clinical trial for moderate osteoarthritis of the knee has completed.
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CLINICAL_TRIALS trial_result · 2012-04-25Clinical Trial Update: Evicel Study on the Peri-operative Bleeding in Total Knee Prothesis Surgery [Phase 4]
Phase 4 trial update assessing Evicel (fibrin sealant) for perioperative bleeding in total knee arthroplasty; current status is UNKNOWN.
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CLINICAL_TRIALS trial_result · 2012-03-22Clinical Trial Update: Perioperative Analgesia for Knee Arthroplasty (PAKA) [Phase 4]
Phase 4 trial update on perioperative analgesia for knee arthroplasty (PAKA) completed. Sponsored by the University of Warwick.
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CLINICAL_TRIALS trial_result · 2012-03-15Clinical Trial Update: Effectiveness of Exercise Programs Following Total Hip and Knee Joint Arthroplasty [NA]
The document reports a completed clinical trial evaluating the effectiveness of exercise programs following total hip and knee arthroplasty.
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CLINICAL_TRIALS trial_result · 2012-02-08Clinical Trial Update: Effect of Tai Chi on Osteoarthritic Knee Pain in Elders With Mild Dementia [NA]
A completed clinical trial (NCT01528566) evaluating whether Tai Chi reduces knee pain from osteoarthritis in elderly individuals with mild d…
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CLINICAL_TRIALS trial_result · 2012-02-01Clinical Trial Update: Dose Finding Study of Bone Morphogenetic Protein 7 (BMP-7) in Subjects With Osteoarthritis (OA) of the Knee [Phase 2]
A Phase 2 dose-finding study of Bone Morphogenetic Protein 7 (BMP-7) in knee osteoarthritis has completed, sponsored by Stryker Biotech.
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CLINICAL_TRIALS trial_result · 2012-02-01Clinical Trial Update: Double-Blind, Randomized, Single Dose Escalation Safety Study of Intraarticular Bone Morphogenic Protein (38A BMP-7) in Subjects With Osteoarthritis (OA) of the Knee [Phase 1]
Phase 1 double-blind, randomized, single-dose safety study of intraarticular bone morphogenetic protein-7 (BMP-7) for osteoarthritis of the …
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CLINICAL_TRIALS trial_result · 2012-01-19Clinical Trial Update: A Study of the Safety and Efficacy of Hylan G-F 20 (Synvisc) in Patients With Symptomatic Osteoarthritis of the Knee [Phase 3]
Phase 3 study evaluating safety and efficacy of Synvisc (hylan G-F 20) for symptomatic osteoarthritis of the knee has completed, with result…
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CLINICAL_TRIALS trial_result · 2012-01-06Clinical Trial Update: Influence of Weight Loss or Exercise on Cartilage in Obese Knee Osteoarthritis Patients [NA]
Update on a completed clinical trial examining whether weight loss or exercise affects knee cartilage in obese patients with knee osteoarthr…
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CLINICAL_TRIALS trial_result · 2012-01-05Clinical Trial Update: Articular Cartilage Resurfacing With Mesenchymal Stem Cells In Osteoarthritis Of Knee Joint [Phase 1]
Phase 1 trial evaluating autologous mesenchymal stem cell resurfacing for knee osteoarthritis has completed.
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CLINICAL_TRIALS trial_result · 2012-01-05Clinical Trial Update: Autologous Transplantation of Mesenchymal Stem Cells (MSCs) and Scaffold in Full-thickness Articular Cartilage [Phase 1]
Phase 1 study evaluating autologous mesenchymal stem cell transplantation with a scaffold for full-thickness articular cartilage in knee ost…
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CLINICAL_TRIALS trial_result · 2011-12-08Clinical Trial Update: A Study of the Safety and Efficacy of REGN475(SAR164877) in Patients With Osteoarthritis of the Knee [Phase 1, Phase 2]
A Phase 1/2 study evaluating the safety and preliminary efficacy of REGN475 (SAR164877) in patients with osteoarthritis of the knee has comp…