Osteoarthritis of the Knee
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CLINICAL_TRIALS trial_result · 2013-06-10Clinical Trial Update: Transplantation of Bone Marrow Derived Mesenchymal Stem Cells in Affected Knee Osteoarthritis by Rheumatoid Arthritis [Phase 2, Phase 3]
A completed Phase 2 and Phase 3 trial evaluating transplantation of bone marrow–derived mesenchymal stem cells for knee osteoarthritis assoc…
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CLINICAL_TRIALS trial_result · 2013-05-31Clinical Trial Update: Clinical Efficacy Study Comparing VisionScope Imaging (VSI) to Magnetic Resonance Imaging (MRI) in Injuries of the Knee [NA]
A completed clinical efficacy study compared VisionScope Imaging (VSI) to MRI for knee injuries, including meniscal tears, loose bodies, and…
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CLINICAL_TRIALS trial_result · 2013-05-21Clinical Trial Update: A Study Of The Safety And Efficacy Of PF-04191834 In Patients With Osteoarthritis Of The Knee [Phase 2]
A Phase 2 study of PF-04191834 for osteoarthritis of the knee was terminated, and results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-05-21Clinical Trial Update: Efficacy and Safety of Single, Low-dose Dexamethasone in Patients After Total Knee Arthroplasty [Phase 4]
Phase 4 trial assessing the efficacy and safety of a single low-dose dexamethasone given after total knee arthroplasty in patients with knee…
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CLINICAL_TRIALS trial_result · 2013-05-17Clinical Trial Update: Aerobic Exercise Intervention for Knee Osteoarthritis [NA]
This update notes the completion of a Mayo Clinic-sponsored clinical trial evaluating aerobic exercise as an intervention for knee osteoarth…
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CLINICAL_TRIALS trial_result · 2013-05-15Clinical Trial Update: A Study of ABT-652 in Combination With a Nonsteroidal Anti-Inflammatory Drug (NSAID) in Adults With Osteoarthritis Pain of the Knee [Phase 2]
A Phase 2 study evaluating ABT-652 in combination with a nonsteroidal anti-inflammatory drug for knee osteoarthritis pain has completed.
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CLINICAL_TRIALS trial_result · 2013-05-08Clinical Trial Update: Preoperative Alignment of Total Knee Replacement [Phase 3]
Phase 3 clinical trial update on preoperative alignment for total knee replacement; results have been posted.
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CLINICAL_TRIALS trial_result · 2013-05-03Clinical Trial Update: Assays for and Reversal of New Anticoagulants
Clinical trial update describing assays and reversal approaches for newer anticoagulants, with relevance to patients with atrial fibrillatio…
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CLINICAL_TRIALS trial_result · 2013-04-23Clinical Trial Update: Echogenic Versus Stimulating Needle and Catheter for Sciatic Blocks [Phase 3]
This entry reports the completion of a Phase 3 trial comparing echogenic versus stimulating needles and catheters for sciatic nerve blocks, …
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CLINICAL_TRIALS trial_result · 2013-03-25Clinical Trial Update: The Use of Fibrin Sealant to Reduce Bleeding After Total Knee Replacement [NA]
A completed clinical trial evaluated whether fibrin sealant can reduce bleeding after total knee replacement.
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CLINICAL_TRIALS trial_result · 2013-03-14Clinical Trial Update: Efficacy Study of Neridronate to Treat Painful Osteoarthritis of the Knee With Bone Marrow Lesions. [Phase 2]
A Phase 2 clinical trial evaluating neridronate for pain in knee osteoarthritis with bone marrow lesions; the current status is unknown.
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CLINICAL_TRIALS trial_result · 2013-03-06Clinical Trial Update: Gait Retraining to Reduce Knee Osteoarthritis Pain [Phase 1, Phase 2]
Update on a gait retraining intervention for knee osteoarthritis, studied in a combined Phase 1/Phase 2 trial and now completed.
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CLINICAL_TRIALS trial_result · 2013-03-06Clinical Trial Update: Early Ambulation After Adductor Canal Block for Total Knee Arthroplasty [NA]
The study evaluating early ambulation after adductor canal block for total knee arthroplasty was terminated.
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CLINICAL_TRIALS trial_result · 2013-02-22Clinical Trial Update: Accuracy of MRI-based Patients Matched Instruments vs Jig-based Instruments in Total Knee Arthroplasty (TKA) [NA]
This completed clinical trial update evaluates the accuracy of MRI-based, patient-matched instruments versus traditional jig-based instrumen…
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CLINICAL_TRIALS trial_result · 2013-02-15Clinical Trial Update: Scorpio® Cruciate Retaining (CR) Outcomes Study [NA]
The Scorpio Cruciate Retaining knee replacement outcomes study was terminated, with results posted in February 2013.
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CLINICAL_TRIALS trial_result · 2013-02-07Clinical Trial Update: Cost-Effectiveness of Web-Based Follow Ups [NA]
Completed clinical trial evaluating the cost-effectiveness of web-based follow-ups for patients with knee or hip osteoarthritis.
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CLINICAL_TRIALS trial_result · 2013-01-25Clinical Trial Update: Periarticular Multimodal Drug Injections in Total Knee Arthroplasty [Phase 4]
Phase 4 clinical trial evaluating periarticular multimodal drug injections in total knee arthroplasty; results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-01-23Clinical Trial Update: Efficacy of Spearmint Tea in Relieving Osteoarthritis of the Knee [Phase 4]
Phase 4 clinical trial update showing efficacy of spearmint tea in relieving symptoms of osteoarthritis of the knee.
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CLINICAL_TRIALS trial_result · 2013-01-21Clinical Trial Update: Knee Arthroplasty Performed With Conventional and Customized Instrumentation [Phase 4]
A Phase 4 clinical trial evaluating conventional versus customized instrumentation in knee arthroplasty has completed, with results posted i…
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CLINICAL_TRIALS trial_result · 2013-01-07Clinical Trial Update: A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee [Phase 2]
Phase 2 trial of ABT-652 in adults with osteoarthritis of the knee has completed, with no results detailed in the update.
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CLINICAL_TRIALS trial_result · 2012-12-12Clinical Trial Update: A Safety And Tolerability Study Of PF-05089771 In Healthy Subjects And In Subjects With Otseoarthritis Of The Knee [Phase 1]
A Phase 1 safety and tolerability study of PF-05089771 in healthy subjects and in individuals with osteoarthritis of the knee has completed.
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CLINICAL_TRIALS trial_result · 2012-11-21Clinical Trial Update: The Efficacy and Safety of Intraarticular Sodium Hyaluronate (Hyalgan) After Proximal Tibial Osteotomy in Treatment of Knee Osteoarthritis Patients [Phase 2]
Phase 2 clinical trial evaluating efficacy and safety of intraarticular Hyalgan (sodium hyaluronate) after proximal tibial osteotomy in knee…
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CLINICAL_TRIALS trial_result · 2012-11-21Clinical Trial Update: Study of Evaluating the Duration of Efficacy of One Intra Articular Injection of Sodium Hyaluronate 2.0% in Patients With Painful Osteoarthritis of the Knee [Phase 2]
This document reports on a Phase 2 clinical trial evaluating the duration of efficacy of a single intra-articular injection of 2.0% sodium h…
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CLINICAL_TRIALS trial_result · 2012-11-07Clinical Trial Update: Is Botox Effective in Relieving Pain From Knee Osteoarthritis? [Phase 1]
A Phase 1 trial sponsored by Mayo Clinic evaluated whether Botox (onabotulinumtoxinA) can relieve pain in knee osteoarthritis; the study sta…
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CLINICAL_TRIALS trial_result · 2012-10-23Clinical Trial Update: Cupping in Osteoarthritis of the Knee [NA]
This clinical trial update notes that the study evaluating cupping for osteoarthritis of the knee has completed.