Osteoarthritis of the Knee
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CLINICAL_TRIALS trial_result · 2016-12-30Clinical Trial Update: A Long-Term, Placebo-Controlled X-Ray Study Investigating the Safety and Efficacy of SD-6010 in Subjects With Osteoarthritis of the Knee [Phase 2]
Pfizer conducted a long-term, placebo-controlled phase 2 study to evaluate the safety and efficacy of SD-6010 in osteoarthritis of the knee;…
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CLINICAL_TRIALS trial_result · 2016-12-20Clinical Trial Update: Effects of Music Listening on Pain and Patient Satisfaction Within First 48 Hours After Knee Replacment Surgery [NA]
A completed clinical trial examined whether listening to music within 48 hours after total knee replacement reduces pain and improves patien…
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CLINICAL_TRIALS trial_result · 2016-12-13Clinical Trial Update: Apitox, Honeybee Toxin for Pain and Inflammation of Osteoarthritis [Phase 3]
A Phase 3 trial evaluating Apitox (honeybee venom toxin) for pain and inflammation in knee osteoarthritis has completed.
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CLINICAL_TRIALS trial_result · 2016-12-06Clinical Trial Update: Safety and Tolerability of 4975 in the Treatment of Moderate to Severe Knee Pain Due to Osteoarthritis (OA) [Phase 2]
Phase 2 trial evaluating the safety and tolerability of 4975 for moderate-to-severe knee pain due to osteoarthritis, which has completed.
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CLINICAL_TRIALS trial_result · 2016-12-02Clinical Trial Update: A Study of Siriraj Home Exercises Protocol for Primary Osteoarthritis of the Knee [NA]
This update notes the completed status of a clinical trial evaluating the Siriraj Home Exercises Protocol for osteoarthritis of the knee.
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CLINICAL_TRIALS trial_result · 2016-11-25Clinical Trial Update: Regional Prophylactic Vancomycin in Revision Total Knee Replacement [Phase 2, Phase 3]
Phase 2/3 clinical trial update evaluating regional prophylactic vancomycin for preventing infection in revision total knee replacement; the…
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CLINICAL_TRIALS trial_result · 2016-11-17Clinical Trial Update: Fully Disposable Patient-Specific Instrumentation [NA]
The clinical trial NCT02966613 evaluating fully disposable patient-specific instrumentation for knee osteoarthritis has completed.
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: Evaluation of Motor Sparing Knee Block to Infiltration Analgesia for Pain Following Knee Arthroplasty [Phase 3]
Phase 3 clinical trial evaluating a motor-sparing knee block used with infiltration analgesia to manage pain after knee arthroplasty.
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CLINICAL_TRIALS trial_result · 2016-11-03Clinical Trial Update: A Multi-Center Actual-Use Study on the Safety of CL 108 for the Treatment of Moderate to Severe Acute Pain Associated With Osteoarthritis of the Knee or Hip [Phase 3]
A multi-center Phase 3 actual-use study completed evaluating the safety of CL 108 for moderate to severe acute pain associated with osteoart…
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CLINICAL_TRIALS trial_result · 2016-10-28Clinical Trial Update: Celution Prepared Adipose Derived Regenerative Cells in the Treatment of Osteoarthritis of the Knee [Phase 2]
Phase 2 trial of Celution Prepared Adipose Derived Regenerative Cells for osteoarthritis of the knee has completed.
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CLINICAL_TRIALS trial_result · 2016-10-26Clinical Trial Update: Shoe Lifts for Leg Length Inequality in Adults With Knee or Hip Symptoms [NA]
Completed clinical trial evaluating shoe lifts for leg length inequality in adults with knee or hip osteoarthritis symptoms; results were po…
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CLINICAL_TRIALS trial_result · 2016-10-21Clinical Trial Update: Liposomal Bupivacaine Versus Standard Analgesia in Total Joint Arthroplasty (TJA) [NA]
A completed clinical trial comparing liposomal bupivacaine to standard analgesia in total joint arthroplasty has posted results in 2016.
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CLINICAL_TRIALS trial_result · 2016-10-10Clinical Trial Update: Effects of Perioperative Intravenous Dexamethasone on the Severity of Persistent Postsurgical Pain After Total Knee Arthroplasty : A Prospective, Randomized, Double-blind, Placebo-controlled Trial [Phase 4]
A Phase 4 randomized, double-blind, placebo-controlled trial evaluating whether perioperative intravenous dexamethasone reduces the severity…
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CLINICAL_TRIALS trial_result · 2016-10-10Clinical Trial Update: Phase IV Clinical Trial to Evaluate the Efficacy and Safety of PlbCR and Aceclofenac in the Treatment of Patients With Osteoarthritis of the Knee [Phase 4]
Phase IV trial update evaluating the efficacy and safety of PlbCR and aceclofenac in knee osteoarthritis.
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CLINICAL_TRIALS trial_result · 2016-09-30Clinical Trial Update: Sleep, Pain and Inflammatory Processes in Older Adults With Osteoarthritis [NA]
This is a completed clinical trial investigating sleep, pain, and inflammatory processes in older adults with osteoarthritis of the knee and…
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CLINICAL_TRIALS trial_result · 2016-09-27Clinical Trial Update: Computer-Assisted Total Knee Replacement Kinematics: DePuy Sigma Posterior Cruciate Substituting Knee and the DePuy Sigma RP Rotating Platform Knee [Phase 4]
Phase 4 clinical trial update noting completion of a computer-assisted total knee replacement study evaluating DePuy Sigma posterior cruciat…
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CLINICAL_TRIALS trial_result · 2016-09-23Clinical Trial Update: Dartmouth-Hitchcock GreenCare Registry for Total Knee Replacement
The Dartmouth-Hitchcock GreenCare Registry for total knee replacement has completed. This update summarizes the registry's completion status…
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CLINICAL_TRIALS trial_result · 2016-09-14Clinical Trial Update: The Three-dimensional Gait Analysis of Medial Knee Osteoarthritis
A completed clinical trial evaluating three-dimensional gait analysis in medial knee osteoarthritis.
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CLINICAL_TRIALS trial_result · 2016-08-26Clinical Trial Update: Comorbidities and Indirect Health State Utility in Hip and Knee Osteoarthritis
A completed clinical trial update examining how comorbidities affect indirect health state utility in patients with hip and knee osteoarthri…
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CLINICAL_TRIALS trial_result · 2016-08-25Clinical Trial Update: Hydros and Hydros-TA Joint Therapy for Pain Associated With Knee Osteoarthritis [Phase 3]
Phase 3 trial of Hydros and Hydros-TA Joint Therapy for knee osteoarthritis has completed.
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CLINICAL_TRIALS trial_result · 2016-08-16Clinical Trial Update: Auriculotherapy for Osteoarthritis Knee [Phase 3]
Phase 3 clinical trial evaluating auriculotherapy for osteoarthritis of the knee has completed.
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CLINICAL_TRIALS trial_result · 2016-08-03Clinical Trial Update: The Effect on Knee Joint Loads of Analgesic Use Compared With Exercise in Patients With Knee Osteoarthritis - An RCT [NA]
This update notes the completion of a randomized controlled trial comparing analgesic use versus exercise to assess knee joint loads in pati…
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CLINICAL_TRIALS trial_result · 2016-07-28Clinical Trial Update: Intraarticular Ozone Therapy for Pain Control in Osteoarthritis of the Knee [Phase 2]
Phase 2 clinical trial evaluating intraarticular ozone therapy for pain control in knee osteoarthritis; the study was terminated.
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CLINICAL_TRIALS trial_result · 2016-07-22Clinical Trial Update: Low Dose Peri- Operative Intra Venous Teranexamic Acid Reduces Blood Loss After Total Knee Arthroplasty: A Double Blind Randomized Placebo Controlled Clinical Trial [NA]
A double-blind randomized placebo-controlled trial found that low-dose perioperative intravenous tranexamic acid reduces blood loss after to…
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CLINICAL_TRIALS trial_result · 2016-07-20Clinical Trial Update: PFC Sigma Fixed and Mobile Knee Study [Phase 4]
This Phase 4 trial of the PFC Sigma fixed and mobile knee prosthesis for osteoarthritis of the knee was terminated, with results posted.