Osteoarthritis of the Knee
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CLINICAL_TRIALS trial_result · 2022-12-22Clinical Trial Update: Study of Pain Catastrophizing [NA]
Clinical trial completion update for a study on pain catastrophizing in knee osteoarthritis; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-11-14Clinical Trial Update: A Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Naproxen for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip [Phase 3]
Phase 3 trial assessing safety and efficacy of fasinumab versus placebo and naproxen for osteoarthritis of the knee or hip; study completed …
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CLINICAL_TRIALS trial_result · 2022-11-01Clinical Trial Update: Efficacy of Flavocoxid 500 mg Compared With Naproxen 500 mg in Subjects With Moderate-severe Osteoarthritis of the Knee [NA]
A completed clinical trial comparing flavocoxid 500 mg with naproxen 500 mg for moderate-severe knee osteoarthritis; results posted.
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CLINICAL_TRIALS trial_result · 2022-10-05Clinical Trial Update: Study of Ampion for the Treatment of Pain and Function in Patients With Severe Osteoarthritis of the Knee. [Phase 3]
Phase 3 study of Ampion for severe knee osteoarthritis was terminated; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-10-05Clinical Trial Update: Efficacy of Cannabidiol in Knee Osteoarthritis [Phase 4]
Phase 4 trial update evaluating cannabidiol for osteoarthritis of the knee, focusing on efficacy.
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CLINICAL_TRIALS trial_result · 2022-10-03Clinical Trial Update: Open Label Extension to Assess the Safety of Long-Term Treatment With Ampion for Severe Osteoarthritis (OA) of the Knee [Phase 3]
Open-label extension study assessing long-term safety of Ampion in severe knee osteoarthritis; terminated with posted results.
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CLINICAL_TRIALS trial_result · 2022-09-30Clinical Trial Update: A Study to Evaluate Safety of Three Intra-articular Injections of Ampion in the Knee of Adults With Osteoarthritis Pain [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating safety of three intra-articular injections of Ampion in the knee for osteoarthritis; completed with resu…
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CLINICAL_TRIALS trial_result · 2022-09-29Clinical Trial Update: Effects of Denosumab on Bone Microarchitecture After Total Knee Arthroplasty [Phase 4]
Phase 4 clinical trial evaluating denosumab effects on bone microarchitecture after total knee arthroplasty in patients with osteoarthritis …
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CLINICAL_TRIALS trial_result · 2022-08-29Clinical Trial Update: A Multiple Injection Study Evaluating Safety and Efficacy of Ampion in Osteoarthritis [Phase 3]
Phase 3 trial update on Ampion for osteoarthritis of the knee; study completed with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-08-25Clinical Trial Update: Durolane Compared to Saline in Patients With Unilateral Knee Osteoarthritis [Phase 4]
Phase 4 clinical trial evaluating Durolane versus saline in patients with unilateral knee osteoarthritis has completed.
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CLINICAL_TRIALS trial_result · 2022-08-09Clinical Trial Update: A Randomized, Controlled Study to Evaluate Efficacy and Safety of Intra-articular Ampion for Osteoarthritis Pain in Knee [Phase 3]
A Phase 3 randomized study evaluated the efficacy and safety of intra-articular Ampion for knee osteoarthritis; the trial is completed with …
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CLINICAL_TRIALS trial_result · 2022-08-08Clinical Trial Update: A Study to Evaluate the Efficacy & Safety of an Intra-Articular Ampion Injection for Pain of Osteoarthritis of the Knee [Phase 3]
Phase 3 trial evaluating intra-articular Ampion injections for knee osteoarthritis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-08-08Clinical Trial Update: AP-003-C Study to Confirm the Efficacy of Ampion™ in Adults With Pain Due to Severe Osteoarthritis of the Knee [Phase 3]
Phase 3 trial update for Ampion in adults with severe knee osteoarthritis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-07-21Clinical Trial Update: A Clinical Study to Test Efficacy and Safety of Repeat Doses of CNTX-4975-05 in Patients With Osteoarthritis Knee Pain [Phase 3]
Phase 3 trial update for CNTX-4975-05 assessing efficacy and safety in osteoarthritis knee pain has completed with posted results.
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CLINICAL_TRIALS trial_result · 2022-07-07Clinical Trial Update: Safety of Total Knee Replacement Surgery Before and After the Implementation of Enhanced Recovery Program
A completed clinical trial assessing safety of total knee replacement surgery before and after implementing an Enhanced Recovery Program.
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CLINICAL_TRIALS trial_result · 2022-06-30Clinical Trial Update: An Efficacy and Safety Study of Two Doses of Intra-Articular Ampion Injection for Pain of Osteoarthritis of the Knee [Phase 2]
Phase 2 trial assessing two doses of intra-articular Ampion for knee osteoarthritis completed with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-05-06Clinical Trial Update: Single-Dose Administration Trial of TLC599 in Osteoarthritis of the Knee [Phase 1, Phase 2]
Clinical trial update for a single-dose TLC599 in osteoarthritis of the knee shows completed Phase 1/2 study with posted results.
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CLINICAL_TRIALS trial_result · 2022-05-05Clinical Trial Update: Clinical Trial of YYC301 P3 for Treatment of Osteoarthritis of the Knee [Phase 3]
Phase 3 clinical trial update for YYC301 in knee osteoarthritis; current status is UNKNOWN.
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CLINICAL_TRIALS trial_result · 2022-04-26Clinical Trial Update: Effect of Duloxetine on Opioid Use After Total Knee Arthroplasty [Phase 4]
A Phase 4 trial evaluated whether duloxetine reduces opioid use after total knee arthroplasty; results were posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-04-26Clinical Trial Update: Efficacy of Cooled and Monopolar Radiofrequency Ablation of the Geniculate Nerves for the Treatment of Chronic Osteoarthritic Knee Pain [NA]
Termination of the trial evaluating cooled and monopolar radiofrequency ablation of geniculate nerves for chronic knee osteoarthritis with r…
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CLINICAL_TRIALS trial_result · 2022-04-14Clinical Trial Update: RCT, Blinded, 2-Arm Efficacy Study of IP and Placebo in Patients With Chronic Pain Related to Osteoarthritis of the Knee [Phase 3]
A Phase 3 randomized, blinded, two-arm efficacy study evaluating IP vs placebo in chronic knee osteoarthritis pain.
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CLINICAL_TRIALS trial_result · 2022-04-08Clinical Trial Update: A Phase 3 Efficacy and Safety Study of Intra-articular CNTX-4975-05 (Capsaicin) vs Placebo in Subjects With OA Knee Pain [Phase 3]
Phase 3 study comparing intra-articular CNTX-4975 (capsaicin) to placebo in knee osteoarthritis shows completed results with posted results.
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CLINICAL_TRIALS trial_result · 2022-03-31Clinical Trial Update: Phenol Neurolysis of Genicular Nerves for Osteoarthritic Knee Pain [Phase 4]
Phase 4 trial update exploring phenol neurolysis of genicular nerves to treat knee osteoarthritis pain.
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CLINICAL_TRIALS trial_result · 2022-03-21Clinical Trial Update: Mesenchymal Stem Cell Therapy for Knee Osteoarthritis [Phase 1, Phase 2]
Clinical trial update for mesenchymal stem cell therapy targeting knee osteoarthritis in Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2022-03-04Clinical Trial Update: Postoperative Pain Control After Periarticular Injection During Total Knee Arthroplasty [Phase 4]
Phase 4 clinical trial update on postoperative pain control after periarticular injection in total knee arthroplasty; study terminated with …