Osteoarthritis of the Knee
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Determining the Optimal Dose of AD-211 in Patients With Osteoarthritis of the Knee [Phase 2]
Clinical trial update announcing a Phase 2 study to determine the optimal dose of AD-211 for osteoarthritis of the knee, currently not recru…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: The Efficacy of Transcutaneous Pulsed Radiofrequency Acupuncture for Knee Osteoarthritis [NA]
This clinical trial update describes an ongoing study evaluating transcutaneous pulsed radiofrequency acupuncture for knee osteoarthritis, w…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Comparative Efficacy of Intra-articular vs. MRI-guided Extra-articular Dextrose Injections in Knee Osteoarthritis Management [NA]
An ongoing trial comparing intra-articular dextrose injections with MRI-guided extra-articular dextrose injections for knee osteoarthritis t…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Kinematic vs Mechanical Alignment in High Tibial Osteotomy [NA]
Clinical trial comparing kinematic vs mechanical alignment in high tibial osteotomy for knee osteoarthritis with genu varum; recruitment has…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Safety and Performance Study of the Legion Porous System in Total Knee Arthroplasty
This is a clinical trial update on the safety and performance study of the Legion Porous System used in total knee arthroplasty. The study i…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Motor Imagery and Action Observation Training in Total Knee Arthroplasty [NA]
This trial update describes a study evaluating motor imagery and action observation training as part of total knee arthroplasty to support r…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Ambispective Multicentric Study Evaluating UKA With U-Knee/Uni-Kroma Implants
This clinical trial update describes an ambispective multicenter study evaluating unicompartmental knee arthroplasty implants U-Knee and Uni…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Quadriceps Muscle Quality and Clinical Outcomes in Knee Osteoarthritis
This entry reports an ongoing clinical trial evaluating quadriceps muscle quality and clinical outcomes in knee osteoarthritis, currently en…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Robot-Aided Off-Axis Neuromuscular Training for Knee OA [NA]
Clinical trial update for robot-aided off-axis neuromuscular training for knee osteoarthritis; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Pivotal Study on the NOVABLOC System for Patients Undergoing Primary Total Knee Arthroplasty [NA]
Synaptrix, Inc. reports a pivotal clinical trial evaluating the NOVABLOC System in patients undergoing primary total knee arthroplasty; the …
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain [Phase 2]
Phase 2 master protocol trial LY900028 evaluating multiple intervention-specific appendices in adults with chronic pain, including knee oste…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: "The Effect of Adductor Canal Block Performed With Postoperative Thigh Tourniquet Application on Pain After Total Knee Arthroplasty" [NA]
This clinical trial update describes an ongoing study evaluating analgesic outcomes of an adductor canal block performed with a postoperativ…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Oral Steroid Taper After Total Knee Arthroplasty [Phase 1]
Phase 1 clinical trial update evaluating an oral steroid taper after total knee arthroplasty for knee osteoarthritis; the study is currently…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Femoral Triangle Block vs Adductor Canal Block on Early Quadriceps Function After Total Knee Arthroplasty [NA]
Clinical trial comparing femoral triangle block to adductor canal block for early quadriceps function after total knee arthroplasty; the stu…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Feasibility of Good Boost+ for Adults Awaiting Total Knee Replacement [NA]
This clinical trial update reports a feasibility study of Good Boost+ for adults awaiting total knee replacement. The study is not yet recru…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis [Phase 3]
Phase 3 pivotal trial evaluating CARTISTEM against a surgical comparator for knee cartilage defects and osteoarthritis is currently recruiti…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: COMPARATIVE EFFECTIVENESS OF EXERCISE, COGNITIVE BEHAVIOURAL THERAPY, AND THEIR COMBINATION FOR PEOPLE WITH CHRONIC MUSCULOSKELETAL PAIN AND POOR SLEEP: SLEEPFIT TRIAL [NA]
Clinical trial update describing the SleepFit study comparing exercise, cognitive behavioral therapy, and their combination for chronic musc…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: The Impact of Single-shot Adductor Canal Block Versus Continuous Femoral Nerve Block on Rehabilitation After Total Knee Replacement [NA]
This study compares single-shot adductor canal block to continuous femoral nerve block for rehabilitation after total knee replacement. It i…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: The GORUN Study: Gradual Onset of RUNning and Knee Joint Health in Novice Runners [NA]
This is a clinical trial update for the GORUN Study examining knee joint health in novice runners with osteoarthritis of the knee; the study…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Imageless Navigation Versus Image-Based Navigation in Robotic-Assisted Total Knee Arthroplasty for Knee Osteoarthritis [NA]
A clinical trial is evaluating imageless navigation versus image-based navigation in robotic-assisted total knee arthroplasty for knee osteo…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Hydrogel Assessment for Local Treatment of Osteoarthritis [NA]
Clinical trial update on a hydrogel-based local treatment for knee osteoarthritis; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: ROSA Knee Intraoperative Planning Flexibility Study
This update indicates that the ROSA Knee intraoperative planning flexibility study sponsored by Zimmer Biomet is currently recruiting partic…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Condylar Offset and Outcomes in Primary Total Knee Arthroplasty
Clinical trial evaluating condylar offset and outcomes in primary total knee arthroplasty; currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Phase 1/2a to Evaluate the Safety and Efficacy of Adipose Tissue Allograft (BRC-OA) in Patients With Osteoarthritis of the Knee [Phase 1, Phase 2]
Phase 1/2a clinical trial investigating the safety and efficacy of Adipose Tissue Allograft (BRC-OA) for osteoarthritis of the knee; status …
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Long Duration High Frequency Ultrasound for the Treatment of Osteoarthritis [Phase 2]
Phase 2 clinical trial evaluating long duration high-frequency ultrasound as a treatment for osteoarthritis of the knee; recruitment has not…