Oropharyngeal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-18Clinical Trial Results: HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers [Phase 1, Phase 2]
Phase 1/2 trial evaluating HPV vaccine PRGN-2009 alone or with anti-PD-L1/TGF-beta trap M7824 in HPV-associated cancers; study completed wit…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Lymphocyte-Sparing And Radio-Immunotherapy in Head and Neck Carcinoma [Phase 3]
A Phase 3 clinical trial evaluating lymphocyte-sparing radio-immunotherapy for head and neck cancers is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Center for Immuno-Oncology Studies
The document provides an update to the gene therapy follow-up protocol for subjects previously enrolled in NCI Center for Immuno-Oncology st…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer [Phase 2]
This Phase 2 clinical trial is evaluating BMX-001 as a radioprotector added to standard chemoradiation therapy for head and neck cancers and…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer [Phase 2]
Phase 2 clinical trial evaluating reduced radiation therapy with standard-of-care chemotherapy for HPV-positive oropharyngeal cancer; the st…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Oropharynx (OPX) Biomarker Trial
Mayo Clinic is conducting a biomarker-focused clinical trial in patients with HPV-positive and HPV-negative oropharyngeal cancer across stag…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Edtech-HPV: A Community Approach Using Education and Technology to Increase HPV Vaccination [NA]
Clinical trial update on an education- and technology-based program to increase HPV vaccination uptake among parents; the study is currently…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Phase II Randomized-registry Embedded Study of Lymphoscintigraphy for Oropharyngeal Neoplasms to Enable Risk-adapted Nodal Guidance for Robotic Surgery and/or Radiotherapy (LONE-RANGR2) [Phase 2]
Phase II randomized-registry embedded study evaluating lymphoscintigraphy to guide nodal treatment for patients with oropharyngeal cancer un…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Treatment De-Escalation for Favorable Prognosis Human Papilloma Virus (HPV) or p16-Positive Oropharyngeal Cancer Receiving Definitive Radiotherapy [NA]
This clinical trial update describes a study evaluating de-escalation of therapy for patients with favorable-prognosis HPV/p16-positive orop…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: HPV-16/18 E6/E7-Specific T Lymphocytes, Relapsed HPV-Associated Cancers, HESTIA [Phase 1]
Phase 1 trial HESTIA evaluating HPV-16/18 E6/E7-specific T lymphocytes in relapsed HPV-associated cancers has completed.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Blood Tests and Questionnaires in Studying Adherence to Preventative Swallowing Exercises in Participants With Metastatic Head and Neck Cancer
This clinical trial update describes the use of blood tests and questionnaires to study adherence to preventative swallowing exercises in pa…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx Cancer [Phase 1, Phase 2]
This is an update on a Phase 1/2 clinical trial evaluating the vaccine PDS0101 alone or in combination with pembrolizumab for locally advanc…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer [Phase 3]
Phase 3 clinical trial evaluating SPECT-CT guided elective contralateral neck treatment for lateralized oropharyngeal cancer; currently recr…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer [Phase 3]
Phase 3 trial evaluating immunotherapy versus observation in HPV-positive oropharyngeal cancer is active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study [Phase 2]
A Phase 2 immunoMATCH pilot trial (BiCaZO) is evaluating cabozantinib in combination with nivolumab for advanced melanoma and head and neck …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study on Using Cell-Free Tumor DNA (ctDNA) Testing to Decide When to StartRoutine Treatment in People With Human Papilloma Virus (HPV)- Associated Oropharynx Cancer (OPC) [Phase 2]
Phase 2 clinical trial evaluating whether cell-free tumor DNA testing can guide the timing of initiating routine treatment for HPV-associate…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer [Phase 2]
A Phase 2 clinical trial is testing adding chemotherapy or chemo-immunotherapy to standard surgery for advanced head and neck cancers, inclu…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Testing the Addition of M3814 (Peposertib) to Radiation Therapy for Patients With Advanced Head and Neck Cancer Who Cannot Take Cisplatin [Phase 1]
Phase 1 trial evaluating the addition of M3814 (peposertib), a DNA-PK inhibitor, to radiation therapy in patients with advanced head and nec…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Multidimensional and Multimodal Profiling of Oropharyngeal Carcinoma
Clinical trial update on multidimensional and multimodal profiling of oropharyngeal cancer, including HPV-related aspects, currently recruit…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers [Phase 2, Phase 3]
This clinical trial update describes a Phase 2/Phase 3 study evaluating atezolizumab and/or bevacizumab with or without standard chemotherap…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Intensity Modulated Proton or X-Ray Therapy After Surgery for Treatment of Head and Neck Cancer, the HEADLIGHT Study [Phase 2]
This document reports a Phase 2 clinical trial called HEADLIGHT evaluating intensity-modulated proton therapy or conventional X-ray therapy …
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CLINICAL_TRIALS other · 2026-04-06Clinical Trial Update: A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers [Phase 1, Phase 2]
This clinical trial update covers a Phase 1/2 study of a combination immunotherapy regimen for advanced cancers, including HPV-associated ma…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive Cisplatin [Phase 3]
Phase 3 clinical trial update on radiation plus cetuximab versus radiation plus non-cisplatin chemotherapy for head and neck cancer patients…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: BALSTILIMAB on Viral Clearance in HPV+ Oropharyngeal Cancer Patients [Phase 2]
Phase 2 clinical trial update for balstilimab evaluating viral clearance in HPV-positive oropharyngeal cancer.
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Biomarker-Driven Radiation Therapy Dose Reduction After Transoral Robotic Surgery for the Treatment of HPV-Positive Oropharyngeal Cancer [Phase 2]
This Phase 2 trial explores biomarker-guided reduction of radiation therapy dose following transoral robotic surgery for HPV-positive oropha…