Organophosphate Poisoning

• FDA approval · 2016-03-02
  FDA Approved: ATNAA ATROPINE AND PRALIDOXIME CHLORIDE AUTO-INJECTOR — Supplemental Application (Meridian Medical Technologies, LLC)

  FDA approved a supplemental application for the ATNAA atropine and pralidoxime chloride auto-injector from Meridian Medical Technologies, LL…

• CLINICAL_TRIALS trial_result · 2015-12-29
  Clinical Trial Update: Adding Nebulized Salbutamol to Intravenous Atropine and Oxygen in OP Poisoning [Phase 3]

  Phase 3 trial evaluating nebulized salbutamol added to intravenous atropine and oxygen for organophosphate poisoning has completed.

• FDA approval · 2015-12-11
  FDA Approved: DUODOTE — Supplemental Application (Meridian Medical Technologies LLC)

  FDA approved a supplemental application for DUODOTE, a combination of atropine and pralidoxime chloride, submitted by Meridian Medical Techn…

• FDA approval · 2015-12-11
  FDA Approved: ATNAA ATROPINE AND PRALIDOXIME CHLORIDE AUTO-INJECTOR — Supplemental Application (Meridian Medical Technologies, LLC)

  The FDA approved a supplemental application for the ATNAA atropine and pralidoxime chloride auto-injector from Meridian Medical Technologies…

• FDA approval · 2015-09-22
  FDA Approved: DUODOTE — Supplemental Application (Meridian Medical Technologies LLC)

  FDA approved a supplemental application for DUODOTE (atropine and pralidoxime chloride) from Meridian Medical Technologies LLC. The action u…

• Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
• FDA approval · 2015-09-22
  FDA Approved: ATNAA ATROPINE AND PRALIDOXIME CHLORIDE AUTO-INJECTOR — Supplemental Application (Meridian Medical Technologies, LLC)

  FDA approved a supplemental application for ATNAA, the atropine and pralidoxime chloride auto-injector, enabling continued marketing under u…

• FDA approval · 2015-08-10
  FDA Approved: ATROPEN AUTO-INJECTOR — Supplemental Application (Meridian Medical Technologies LLC)

  The FDA approved a supplemental application for the AtroPen Auto-Injector (atropine) from Meridian Medical Technologies LLC. This action upd…

• CLINICAL_TRIALS trial_result · 2015-02-23
  Clinical Trial Update: Farming, Personal Protective Equipment, Nepal [NA]

  A completed clinical trial led by Bispebjerg Hospital evaluated farming practices and personal protective equipment in relation to organopho…

• FDA approval · 2015-02-03
  FDA Approved: ATNAA ATROPINE AND PRALIDOXIME CHLORIDE AUTO-INJECTOR — Supplemental Application (Meridian Medical Technologies, LLC)

  The FDA approved a supplemental application for the ATNAA atropine and pralidoxime chloride auto-injector, updating/expanding its labeling.

• FDA approval · 2015-01-20
  FDA Approved: ATNAA ATROPINE AND PRALIDOXIME CHLORIDE AUTO-INJECTOR — Supplemental Application (Meridian Medical Technologies, LLC)

  FDA approved a supplemental application for the ATNAA atropine and pralidoxime chloride auto-injector (Meridian) under NDA021175.

• FDA approval · 2014-05-15
  FDA Approved: ATNAA ATROPINE AND PRALIDOXIME CHLORIDE AUTO-INJECTOR — Supplemental Application (Meridian Medical Technologies, LLC)

  FDA approved a supplemental application for the ATNAA atropine and pralidoxime chloride auto-injector from Meridian Medical Technologies, af…

• CLINICAL_TRIALS trial_result · 2014-01-20
  Clinical Trial Update: Is the WHO Recommended Dose of Pralidoxime Effective in the Treatment of Organophosphorus Poisoning? [Phase 1]

  A Phase 1 study evaluated whether the WHO-recommended dose of pralidoxime is effective for treating organophosphate poisoning; the trial has…

• FDA approval · 2014-01-15
  FDA Approved: PROTOPAM CHLORIDE — Supplemental Application (Baxter Healthcare Corporation)

  FDA approved a supplemental application for PROTOPAM CHLORIDE (pralidoxime chloride) by Baxter Healthcare Corporation. This action updates t…

• FDA approval · 2013-11-14
  FDA Approved: ATROPEN AUTO-INJECTOR — Supplemental Application (Meridian Medical Technologies LLC)

  FDA approved a supplemental application for the ATROPEN AUTO-INJECTOR (atropine) by Meridian Medical Technologies LLC.

• FDA approval · 2013-05-03
  FDA Approved: PROTOPAM CHLORIDE — Supplemental Application (Baxter Healthcare Corporation)

  The FDA approved a supplemental application for Protopam Chloride (pralidoxime chloride) submitted by Baxter Healthcare Corporation. The act…

• FDA approval · 2013-04-09
  FDA Approved: DUODOTE — Supplemental Application (Meridian Medical Technologies LLC)

  The FDA approved a supplemental application for DUODOTE (atropine and pralidoxime chloride) by Meridian Medical Technologies LLC. The action…

• FDA approval · 2012-11-30
  FDA Approved: PROTOPAM CHLORIDE — Supplemental Application (Baxter Healthcare Corporation)

  FDA approved a supplemental application for PROTOPAM CHLORIDE (pralidoxime chloride) from Baxter Healthcare Corporation.

• CLINICAL_TRIALS withdrawal · 2011-04-05
  Clinical Trial Update: Scopolamine Treatment for Patients With Organophosphate Poisoning [NA]

  The clinical trial evaluating scopolamine for organophosphate-induced neurotoxicity has been withdrawn.

• FDA approval · 2010-09-08
  FDA Approved: PROTOPAM CHLORIDE — Supplemental Application (Baxter Healthcare Corporation)

  The FDA approved a Baxter Healthcare supplemental application for Protopam Chloride (pralidoxime chloride), potentially updating labeling an…

• CLINICAL_TRIALS trial_result · 2010-08-12
  Clinical Trial Update: A Study of Inhaled Atropine Sulfate in Healthy Adults [Phase 1]

  Phase 1 study of inhaled atropine sulfate in healthy adults, evaluating safety and preliminary pharmacology for potential use in organophosp…

• FDA approval · 2006-09-28
  FDA Approved: DUODOTE — Original Application (Meridian Medical Technologies LLC)

  FDA approved DUODOTE, a dual-auto-injector containing atropine and pralidoxime chloride, for emergency treatment of organophosphate poisonin…

• CLINICAL_TRIALS trial_result · 2006-06-06
  Clinical Trial Update: Study to Know the Efficacy of Higher Doses of Pralidoxime in Patients of Organophpsphorus Poisoning. [NA]

  A completed clinical trial evaluated higher doses of pralidoxime for treating organophosphate poisoning.