Oral Cavity Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-08-22Clinical Trial Update: Sintilimab to Prevent High-risk Oral Premalignant Lesions Cancerization [Phase 2]
A Phase 2 trial update on sintilimab aimed at preventing cancerization in high-risk oral premalignant lesions.
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CLINICAL_TRIALS trial_result · 2018-04-09Clinical Trial Update: Docetaxel Based Chemotherapy Plus or Minus Induction Chemotherapy to Decrease Events in Head and Neck Cancer (DeCIDE) [Phase 3]
A Phase 3 trial (DeCIDE) evaluated docetaxel-based chemotherapy with or without induction chemotherapy to reduce events in head and neck can…
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CLINICAL_TRIALS trial_result · 2018-03-13Clinical Trial Update: Fluorouracil, Hydroxyurea, Cetuximab and Twice-daily Intensity Radiation Therapy for Advanced Head and Neck Cancer [Phase 2]
Phase 2 clinical trial evaluating fluorouracil, hydroxyurea, cetuximab with twice-daily intensity-modulated radiation therapy for advanced h…
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CLINICAL_TRIALS trial_result · 2017-08-28Clinical Trial Update: Interstitial Photodynamic Therapy in Treating Patients With Recurrent Head and Neck Cancer [Phase 2]
Phase 2 trial evaluating interstitial photodynamic therapy for recurrent head and neck cancer was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2017-07-28Clinical Trial Update: DAHANCA 28A: Phase I/II Study on Accelerated, Hyperfractionated Radiotherapy With Concomitant Cisplatin and Nimorazole [Phase 1, Phase 2]
Phase I/II trial (DAHANCA 28A) investigates accelerated, hyperfractionated radiotherapy with concomitant cisplatin and nimorazole in head an…
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CLINICAL_TRIALS withdrawal · 2017-06-26Clinical Trial Update: Lenvatinib and Capecitabine in Patients With Advanced Malignancies [Phase 1]
A Phase 1 study of lenvatinib in combination with capecitabine for patients with advanced cancers has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-05-16Clinical Trial Update: Randomized Trial to Assess the Impact of a Screening Program on Upper Aerodigestive Tract Cancer Mortality in a High Risk Population [Phase 3]
A Phase 3 randomized trial assessing whether a cancer screening program lowers mortality from upper aerodigestive tract cancers in a high‑ri…
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: Cisplatin With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer [Phase 2]
Phase 2 trial examining cisplatin with or without the WEE1 inhibitor MK-1775 in recurrent or metastatic head and neck cancers was terminated…
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CLINICAL_TRIALS trial_result · 2017-01-19Clinical Trial Update: Rapamycin Therapy in Head and Neck Squamous Cell Carcinoma [Phase 1, Phase 2]
This document reports a completed Phase 1/2 clinical trial of rapamycin therapy for head and neck squamous cell carcinoma, with results post…
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: Active Immunization of Patients With Carcinoma of Oral Cavity or Oropharynx With Autologous Dendritic Cells Transfected With DNA From Autologous Tumor [Phase 1]
Phase 1 trial of an autologous dendritic cell vaccine transfected with a patient’s tumor DNA for oral cavity and oropharyngeal cancers was t…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: Photodynamic Therapy Using HPPH in Treating Patients With Recurrent Dysplasia, Carcinoma in Situ, or Stage I Oral Cavity Cancer [Phase 1]
Phase 1 trial of photodynamic therapy with HPPH for recurrent dysplasia, carcinoma in situ, or stage I oral cavity cancer; the study sponsor…
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Valproic Acid and Platinum-based Chemoradiation in Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 2]
This Phase 2 study evaluated valproic acid in combination with platinum-based chemoradiation for locally advanced head and neck squamous cel…
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CLINICAL_TRIALS trial_result · 2016-01-29Clinical Trial Update: Smoking Status and Body Image in Oral Cancer Patients
A completed clinical trial update from MD Anderson Cancer Center examining smoking status and body image in patients with oral cavity cancer…
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CLINICAL_TRIALS trial_result · 2015-09-01Clinical Trial Update: Phase II Randomized Trial of the Combination of Cetuximab and Sorafenib or Single Agent Cetuximab [Phase 2]
This Phase II randomized trial assessed cetuximab with sorafenib versus cetuximab alone in metastatic head and neck squamous cell carcinomas…
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CLINICAL_TRIALS research · 2015-07-10Clinical Trial Update: Study to Assess Biomarkers in Patients With Resectable Oral Cavity Cancer Randomized to Receive Preoperative Treatment [Phase 1, Phase 2]
A Phase 1/2 clinical trial investigating biomarkers in patients with resectable oral cavity cancer who receive preoperative treatment.
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CLINICAL_TRIALS trial_result · 2015-05-05Clinical Trial Update: Cediranib Maleate in Treating Patients With Recurrent or Newly Diagnosed Metastatic Head and Neck Cancer [Phase 2]
A Phase 2 trial update for cediranib maleate in patients with recurrent or metastatic head and neck squamous cell carcinoma has completed en…
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CLINICAL_TRIALS trial_result · 2015-02-25Clinical Trial Update: A Study of High-Risk Oral Cavity Cancer [Phase 2, Phase 3]
A Phase 2/3 clinical trial studying high-risk oral cavity cancer has been terminated.
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CLINICAL_TRIALS trial_result · 2014-12-05Clinical Trial Update: Intra-arterial Versus Intravenous Cisplatin, Combined With Radiation, for Oral Cavity and Oropharynx Cancer [EARLY_Phase 1]
An early-phase trial comparing intra-arterial versus intravenous cisplatin with radiation for oral cavity and oropharyngeal cancers was term…
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CLINICAL_TRIALS trial_result · 2014-10-16Clinical Trial Update: Quality of Life and Development of Measures in Patients With Cancer of the Oral Cavity
The study provides a clinical trial update on quality-of-life assessment development for patients with oral cavity cancer. It focuses on cre…
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CLINICAL_TRIALS trial_result · 2014-07-04Clinical Trial Update: Photodynamic Therapy Using Porfimer Sodium in Treating Patients With Recurrent Mouth or Throat Dysplasia or Recurrent In Situ Cancer or Stage I Cancer of the Mouth or Throat [NA]
This ClinicalTrials.gov entry reports termination of a study evaluating photodynamic therapy with porfimer sodium for recurrent mouth or thr…
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CLINICAL_TRIALS research · 2014-06-06Clinical Trial Update: Erlotinib, Docetaxel, and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer [Phase 1]
This Phase 1 clinical trial update examines a combination regimen of Erlotinib, Docetaxel, and radiation therapy for locally advanced head a…
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CLINICAL_TRIALS trial_result · 2013-07-02Clinical Trial Update: Physiotherapy Treatment for Patients Suffering From Head and Neck Cancer [Phase 2]
Phase 2 clinical trial evaluating physiotherapy treatment for head and neck cancer patients, including those with oral cavity cancer and oro…
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CLINICAL_TRIALS trial_result · 2013-02-28Clinical Trial Update: S0420, Sorafenib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer [Phase 2]
This document provides an update on a Phase 2 trial of sorafenib for patients with recurrent or metastatic head and neck cancer and indicate…
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CLINICAL_TRIALS trial_result · 2013-01-24Clinical Trial Update: Bortezomib Followed by the Addition of Doxorubicin at Disease Progression in Treating Patients With Locally Advanced, Recurrent, or Metastatic Adenoid Cystic Carcinoma (Cancer) of the Head and Neck [Phase 2]
This Phase 2 trial update examines bortezomib followed by doxorubicin at progression in patients with locally advanced, recurrent, or metast…
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CLINICAL_TRIALS trial_result · 2012-11-01Clinical Trial Update: Prevention of Radiation-induced Severe Oral Mucositis in Oral Cavity, Oropharynx, Hypopharynx, and Cavum Cancer [Phase 3]
Phase 3 trial evaluating prevention of radiation-induced severe oral mucositis in cancers of the oral cavity, oropharynx, and hypopharynx ha…