Optic Neuritis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-09-23Clinical Trial Update: Long-Term Assessment of Remyelinating Therapy [Phase 2]
Phase 2 clinical trial assessing a remyelinating therapy for acute optic neuritis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-08-12Clinical Trial Update: Effect of Phenytoin on the Ganglion Cell Layer in Patients With Optic Neuritis [Phase 2]
Phase 2 clinical trial evaluating the effect of phenytoin on the ganglion cell layer in patients with optic neuritis has completed with resu…
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CLINICAL_TRIALS trial_result · 2018-05-17Clinical Trial Update: Amiloride Clinical Trial In Optic Neuritis [Phase 2]
A Phase 2 trial of amiloride for optic neuritis has completed.
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CLINICAL_TRIALS withdrawal · 2018-04-12Clinical Trial Update: Induction Therapy With a Single High Dose Bolus of Intravenous Methotrexate With Leucovorin Rescue, Prior to Initiation of AVONEX® Treatment, in Patients Presenting With a First Acute Demyelinating Event. [Phase 4]
Phase 4 trial evaluating induction therapy with a single high-dose intravenous methotrexate with leucovorin rescue prior to AVONEX treatment…
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CLINICAL_TRIALS trial_result · 2017-09-06Clinical Trial Update: Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosis [Phase 4]
Long-term Phase 4 study investigating Avonex therapy after a first attack in multiple sclerosis patients; completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Defining the Functional and Neuro-Protective Potential of ACTHAR in Acute Optic Neuritis [EARLY_Phase 1]
This clinical trial update reports the completion of an early-phase Phase 1 study evaluating ACTHAR's functional and neuroprotective potenti…
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CLINICAL_TRIALS trial_result · 2017-07-07Clinical Trial Update: Pupillometry Dynamic Measures in Patients Without Ocular or Neurological Disease
A completed clinical trial update examining dynamic pupillometry measures in participants without ocular or neurological disease, with optic…
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CLINICAL_TRIALS trial_result · 2017-03-27Clinical Trial Update: Effect of MD1003 in Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis [Phase 3]
Phase 3 study evaluating MD1003 for chronic visual loss related to optic neuritis in multiple sclerosis; current trial status is unknown.
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CLINICAL_TRIALS trial_result · 2016-12-08Clinical Trial Update: Pharmacokinetics, Safety and Tolerability of Single Doses of BIIB033 (Opicinumab) Produced by 2 Manufacturing Processes [Phase 1]
This Phase 1 study reports pharmacokinetics, safety and tolerability of single doses of Opicinumab (BIIB033) produced by two manufacturing p…
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CLINICAL_TRIALS research · 2016-09-01Clinical Trial Update: The Correlation Between AQP-4 Ab and the Visual Function of Patients With Demyelinating ON at Onset
This clinical trial update investigates whether aquaporin-4 antibody status correlates with visual function in patients presenting with demy…
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CLINICAL_TRIALS trial_result · 2016-06-30Clinical Trial Update: BIIB033 In Acute Optic Neuritis (AON) [Phase 2]
Biogen's BIIB033 Phase 2 trial in acute optic neuritis has completed and its results have been posted.
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CLINICAL_TRIALS trial_result · 2016-02-26Clinical Trial Update: Single Oral Doses Study of Nerispirdine on Visual Function in Patients With Multiple Sclerosis [Phase 2]
A Phase 2 clinical trial update evaluating Nerispirdine's impact on visual function in patients with multiple sclerosis, including optic neu…
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CLINICAL_TRIALS trial_result · 2016-02-17Clinical Trial Update: Atacicept in Subjects With Optic Neuritis [Phase 2]
This is a Phase 2 trial update for atacicept in optic neuritis; the study was terminated and results were posted on 2016-02-17.
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CLINICAL_TRIALS trial_result · 2015-09-09Clinical Trial Update: Neuroprotection With Phenytoin in Optic Neuritis [Phase 2]
Phase 2 trial assessing phenytoin for neuroprotection in optic neuritis (with participants also having multiple sclerosis) has completed.
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Optic Neuritis Recovery After Oral or IV Corticosteroids [Phase 2, Phase 3]
This update reports the completion of a Phase 2/3 trial examining recovery from optic neuritis after oral or intravenous corticosteroid ther…
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CLINICAL_TRIALS trial_result · 2015-06-26Clinical Trial Update: Study to Evaluate Eye Function in Patients Taking Linezolid for Six Weeks or Greater [Phase 3]
Phase 3 study evaluating eye function in patients taking Linezolid for six weeks or longer was terminated, with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-05-12Clinical Trial Update: Amiloride Hydrochlorothiazide as Treatment of Acute Inflammation of the Optic Nerve [Phase 2]
This document notes a Phase 2 clinical trial evaluating amiloride hydrochloride with hydrochlorothiazide for acute inflammation of the optic…
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CLINICAL_TRIALS trial_result · 2014-06-03Clinical Trial Update: Optical Coherence Tomography in Multiple Sclerosis Patients
This clinical trial update notes that a study evaluating optical coherence tomography in patients with multiple sclerosis and optic neuritis…
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CLINICAL_TRIALS trial_result · 2013-12-06Clinical Trial Update: Interest of Dynamic Measures of the Pupil in Optic Neuritis
This clinical trial update reports on investigating dynamic pupil measurements in optic neuritis. The study status is completed.
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CLINICAL_TRIALS trial_result · 2013-09-23Clinical Trial Update: A Randomized, Double-blind, Placebo-controlled, Multicenter Study of the Effects of Glatiramer Acetate (GA) on the Retinal Nerve Fiber Layer (RNFL) and Visual Function in Patients With a First Episode of Acute Optic Neuritis (AON). (Octagon) [Phase 3]
A randomized, double-blind, placebo-controlled Phase 3 trial evaluating glatiramer acetate effects on retinal nerve fiber layer and visual f…
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CLINICAL_TRIALS trial_result · 2013-01-23Clinical Trial Update: Neuroprotection and Repair in Optic Neuritis [Phase 2]
Phase 2 trial investigating neuroprotection and repair in optic neuritis was terminated. Conditions include multiple sclerosis and optic neu…
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CLINICAL_TRIALS trial_result · 2012-09-13Clinical Trial Update: Safety and Efficacy Study of Erythropoietin as add-on Therapy of Methylprednisolone to Treat Acute Optic Neuritis [Phase 2]
A Phase 2 completed trial evaluating erythropoietin as an add-on to methylprednisolone for safety and efficacy in acute optic neuritis.
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CLINICAL_TRIALS research · 2011-11-22Clinical Trial Update: Effect of Vitamin D on Retinal Changes in Patient With Optic Neuritis by Optic Coherence Tomography [Phase 2]
Phase 2 clinical trial update investigating the effect of vitamin D on retinal changes in optic neuritis, assessed with optical coherence to…
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CLINICAL_TRIALS trial_result · 2011-08-29Clinical Trial Update: TLR-9 Antagonism in Steroid Resistant Optic Neuritis [NA]
A completed clinical trial evaluated a Toll-like receptor 9 antagonist for steroid-resistant optic neuritis. The provided snippet does not i…
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CLINICAL_TRIALS trial_result · 2011-01-10Clinical Trial Update: Simvastatin Treatment of Patients With Acute Optic Neuritis [Phase 3]
A Phase 3 clinical trial evaluating simvastatin for acute optic neuritis; the study status is UNKNOWN.