Opioid Use Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Evaluation of L-alpha-acetylmethadol (LAAM) in Methadone Patients - 5 [Phase 2]
A Phase 2 clinical trial evaluating L-alpha-acetylmethadol (LAAM) in methadone-maintained patients has completed.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Effects of Buprenorphine/Naloxone Administered in Different Ways For Treating Opioid Dependence [NA]
A clinical trial update on evaluating different administration methods of buprenorphine/naloxone for treating opioid use disorder.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Evaluation of Liquid vs. Tablet Buprenorphine - 6 [Phase 2]
A Phase 2 trial comparing liquid versus tablet buprenorphine formulations for opioid use disorders has completed.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Effects of Buspirone in Opiate Withdrawal [Phase 4]
A Phase 4 clinical trial evaluated the effects of buspirone on opiate withdrawal in individuals with heroin dependence; the study has comple…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Evaluation of Lofexidine for Treatment of Opioid Withdrawal - 3 [Phase 1]
A Phase 1 study evaluated lofexidine for treatment of opioid withdrawal and has completed.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Buprenorphine and Naloxone Combination Study - 10 [Phase 1]
This update reports the completion of a Phase 1 clinical trial evaluating a buprenorphine/naloxone combination for heroin dependence and opi…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Blockade Efficacy of Buprenorphine/Naloxone For Opioid Dependence [NA]
A completed clinical trial sponsored by NIDA evaluated how well buprenorphine/naloxone blocks opioid effects in people with opioid use disor…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Abuse Potential of Buprenorphine and Naloxone in Non-Dependent Opioid Users [NA]
A completed clinical trial evaluated the abuse potential of the buprenorphine/naloxone combination in non-dependent opioid users. The study …
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Evaluation of Lofexidine for Treatment of Opiate Withdrawal - 10 [Phase 1]
Phase 1 trial update on lofexidine for treatment of opiate withdrawal has completed.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Abuse Potential of Buprenorphine/Naloxone [Phase 2]
A Phase 2 trial evaluated the abuse potential of buprenorphine/naloxone in individuals with opioid use disorders. The study was terminated.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Buprenorphine Dose Escalation Trial for Treatment of Non-Dependent Opiate Users - 2 [Phase 1]
Phase 1 dose-escalation trial of buprenorphine for non-dependent opiate users has completed. The study was sponsored by the National Institu…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Vouchers vs. Prizes for Methadone Patients - 1 [NA]
A completed clinical trial comparing voucher versus prize incentives for methadone maintenance patients.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Assessing Abuse Potential of Parenteral Buprenorphine/Naloxone in Non-Dependent Opioid Abusers [NA]
This clinical trial update notes that a study evaluating the abuse potential of parenteral buprenorphine/naloxone in non-dependent opioid ab…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Opioid Agonist and Antagonist Effects on Opioid Dependence [Phase 2]
A Phase 2 clinical trial investigating the effects of opioid agonists and antagonists on opioid dependence has been terminated, according to…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Combined Behavioral and Pharmacologic Treatment of Polydrug Abuse [Phase 1]
This ClinicalTrials.gov update notes the Phase 1 study on combined behavioral and pharmacologic treatment for polydrug abuse (opioid use dis…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Methadone Levels in Breast Milk of Women Taking Methadone for Opiate Addiction - 2
An update from a completed trial examining methadone concentrations in breast milk of women treated for opioid addiction.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Effects of Pre-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals
A completed clinical trial evaluated whether a pre-session supplemental dose of hydromorphone influences drug-seeking behavior in opioid-dep…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Dextromethorphan, Gabapentin, and Oxycodone to Treat Opioid-Induced Hyperalgesia [NA]
A completed clinical trial evaluating a combination of dextromethorphan, gabapentin, and oxycodone for opioid-induced hyperalgesia.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Effects of Buprenorphine/Naloxone in Treating Opioid Dependent Individuals Who Are Maintained on Methadone [NA]
This clinical trial update reports on the evaluation of buprenorphine/naloxone for opioid-dependent individuals maintained on methadone; the…
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CLINICAL_TRIALS trial_result · 2017-01-10Clinical Trial Update: Medication Adherence Therapy for Opioid Abusing Pain Patients [Phase 1, Phase 2]
This clinical trial update reports the completion of Phase 1 and Phase 2 studies evaluating medication adherence therapy for patients with c…
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CLINICAL_TRIALS trial_result · 2017-01-06Clinical Trial Update: Starting Treatment With Agonist Replacement Therapies (START) [Phase 4]
The START Phase 4 trial, conducted at UCLA, reports results from initiating agonist replacement therapies for opioid use disorder.
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CLINICAL_TRIALS trial_result · 2016-12-26Clinical Trial Update: Single Ascending Dose Study of RBP-6000 [Phase 1]
Phase 1 single ascending dose study of RBP-6000 for opioid use disorder has completed, providing early safety and pharmacokinetic data. The …
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FDA approval · 2016-12-16FDA Approved: DISKETS — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approved a supplemental application for DISKETS (methadone hydrochloride) from Hikma Pharmaceuticals USA Inc., reflecting an approved su…
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FDA approval · 2016-12-16FDA Approved: METHADONE HYDROCHLORIDE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approved a supplemental application for methadone hydrochloride from Hikma Pharmaceuticals USA Inc., finalizing the approval of a generi…
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FDA approval · 2016-12-16FDA Approved: METHADOSE — Supplemental Application (SpecGx LLC)
The FDA approved a supplemental application for Methadose (methadone hydrochloride) filed by SpecGx LLC.