Opioid Use Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD) [Phase 1]
A Phase 1 clinical trial at Yale University is investigating the synaptotrophic effects of psilocybin for opioid use disorder and is current…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Developing a Tailored Stigma Reduction Intervention to Increase Buprenorphine Prescribing [NA]
This clinical trial update describes a study sponsored by Ohio University to develop a tailored stigma-reduction intervention aimed at incre…
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CLINICAL_TRIALS trial_result · 2025-05-28Clinical Trial Update: Fostering MAT Use in Justice Populations [NA]
A completed study reports results of an effort to increase the use of medication-assisted treatment for opioid use disorder among justice-in…
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CLINICAL_TRIALS withdrawal · 2025-05-28Clinical Trial Update: Suboxone Dispenser for OUD [NA]
The clinical trial for a Suboxone dispenser targeting Opioid Use Disorder has been withdrawn.
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CLINICAL_TRIALS trial_result · 2025-05-25Clinical Trial Update: Oxytocin, Stress, Craving, Opioid Use Disorder [Phase 1]
Phase 1 trial from Brown University evaluating oxytocin’s effects on stress and craving in individuals with opioid use disorder; results hav…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk [NA]
This clinical trial entry describes the Kentucky Outreach Service Kiosk (KyOSK) initiative to reduce HIV, Hepatitis C, and overdose risk amo…
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: Treatment of Pregnant Women With OUD [NA]
A completed clinical trial sponsored by Yale University investigates treatment for pregnant women with opioid use disorder, with results now…
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: Effectiveness of a CBT-based mHealth Intervention Targeting MOUD Retention, Adherence, and Opioid Use [NA]
This clinical trial update reports on a UCLA-sponsored study evaluating a CBT-based mobile health intervention to improve retention and adhe…
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FDA approval · 2025-05-19FDA Approved: SUBOXONE — Supplemental Application (INDIVIOR INC.)
FDA approved a supplemental application for Suboxone (buprenorphine hydrochloride and naloxone hydrochloride) submitted by Indivior Inc., en…
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FDA approval · 2025-05-19FDA Approved: ZUBSOLV — Supplemental Application (Orexo US, Inc.)
The FDA approved a supplemental application for ZUBSOLV (buprenorphine/naloxone) submitted by Orexo US, Inc.
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: PRimary Care Opioid Use Disorders Treatment (PROUD) Trial [NA]
The PROUD trial investigating opioid-use disorder treatment conducted under Kaiser Permanente has completed; no trial results are provided i…
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Improving Access to Naloxone to Prevent Opioid Overdose Deaths (SAIA-Naloxone) [NA]
This clinical trials registry entry updates the SAIA-Naloxone trial (NCT05886712) sponsored by RTI International, which aims to improve acce…
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EMA approval · 2025-05-16EMA Authorised: Buprenorphine Neuraxpharm (buprenorphine hydrochloride) — Neuraxpharm Pharmaceuticals S.L.
The EMA authorised Buprenorphine Neuraxpharm (buprenorphine hydrochloride) for opioid-related disorders.
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Integrated e-Health (Electronic Health) for HIV and Substance Use Disorders in Justice Involved Women [Phase 4]
A Phase 4 clinical trial conducted by Yale University evaluating integrated e-Health tools for HIV and opioid use disorder in justice-involv…
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: Persistent Pain After Knee Replacement
This entry reports the completion of a clinical trial evaluating persistent postsurgical pain after knee replacement. The update does not pr…
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Long-acting Buprenorphine vs. Naltrexone Opioid Treatments in CJS-involved Adults [Phase 4]
A Phase 4 trial comparing long-acting buprenorphine with naltrexone for opioid use disorder in adults involved with the criminal justice sys…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Efficacy of Buprenorphine and XR-Naltrexone Combination for Relapse Prevention in Opioid Use Disorder [Phase 2, Phase 3]
Clinical trial update indicating the efficacy of a buprenorphine and extended-release naltrexone combination for relapse prevention in opioi…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: "Bupe by the Book": A Tele-Buprenorphine Clinical Trial in Public Libraries With Unstably Housed Persons With Opioid Use Disorder [NA]
A UC San Diego-sponsored trial is evaluating tele-buprenorphine delivery for opioid use disorder in unstably housed individuals; the study i…
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CLINICAL_TRIALS withdrawal · 2025-05-13Clinical Trial Update: OLP to Manage Pain in TJA: A Feasibility Study [EARLY_Phase 1]
A Phase 1 feasibility trial evaluating OLP for pain management in total joint arthroplasty was withdrawn.
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Opioid Treatment and Peer Recovery Support [NA]
Brown University is conducting a clinical trial on opioid treatment and peer recovery support for opioid use disorder, and the study is curr…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Following Outcomes Remotely Within Addiction Recovery Domains
A clinical study sponsored by McLean Hospital is currently recruiting to study remote outcomes within addiction recovery domains for individ…
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CLINICAL_TRIALS trial_result · 2025-05-11Clinical Trial Update: Personally-Tailored Opioid-overdose and Medication for Opioid Use Disorder (MOUD) Education (TOME) for Pregnant and Postpartum Persons in MOUD [NA]
This update reports completion and results posting for a trial evaluating a personalized education program (TOME) for pregnant and postpartu…
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CLINICAL_TRIALS trial_result · 2025-05-11Clinical Trial Update: Project MATLINK: Development and Evaluation of a Screening, Brief Intervention, & Referral to Treatment (SBIRT) Program for Opioid Dependent Prisoners and Probationers Transitioning to the Community [NA]
This completed clinical trial evaluated a Screening, Brief Intervention, and Referral to Treatment (SBIRT) program for opioid-dependent pris…
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CLINICAL_TRIALS trial_result · 2025-05-11Clinical Trial Update: Implementation of STTR Strategies Among People Who Inject Drugs in Malaysia [NA]
A Yale University–sponsored clinical trial in Malaysia evaluating STTR strategies for people who inject drugs has been suspended; participan…
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: PRIDE III Prison Interventions and HIV Prevention Collaboration [NA]
A Yale-led clinical trial, PRIDE III Prison Interventions and HIV Prevention Collaboration, is currently recruiting participants for HIV inf…