Opioid Use Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-04-07Clinical Trial Update: Extended-Release Naltrexone for Opioid Relapse Prevention Following Release From Jail [Phase 3]
A Phase 3 trial evaluating extended-release naltrexone to prevent opioid relapse after release from jail has completed and posted results.
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CLINICAL_TRIALS trial_result · 2016-04-04Clinical Trial Update: Abuse Potential Study of PF-00345439 [Phase 1]
Phase 1 abuse-potential study of PF-00345439 in opioid users has completed.
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CLINICAL_TRIALS trial_result · 2016-03-03Clinical Trial Update: Comparative Evaluation of PUSPENs and C&Cs
The clinical trial NCT02698098 evaluating PUSPENs versus C&Cs for opioid use disorder has been terminated.
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Effects of Pioglitazone, a PPARgamma Receptor Agonist, on the Abuse Liability of Oxycodone [Phase 2]
Phase 2 clinical trial evaluating whether pioglitazone affects the abuse liability of oxycodone in individuals with opioid use disorder; res…
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CLINICAL_TRIALS trial_result · 2016-01-11Clinical Trial Update: Buprenorphine Maintenance Treatment of Opioid Dependence in Primary Care: A Randomized Clinical Trial [Phase 2, Phase 3]
Randomized trial assessing buprenorphine maintenance treatment for opioid dependence in primary care settings, with results posted after com…
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CLINICAL_TRIALS trial_result · 2015-12-02Clinical Trial Update: Effects of Subanesthetic Concentrations of Isoflurane/Nitrous Oxide - 3 [Phase 2]
A Phase 2 clinical trial evaluating subanesthetic concentrations of isoflurane and nitrous oxide in individuals with opioid use disorder and…
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CLINICAL_TRIALS trial_result · 2015-11-18Clinical Trial Update: Efficacy Evaluation of Traditional Chinese Medicine JITAI Combined Comprehensive Model Among Heroin Addicts After Detoxification [NA]
Clinical trial completed evaluating the efficacy of a Traditional Chinese Medicine JITAI-based model for individuals with opioid use disorde…
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CLINICAL_TRIALS trial_result · 2015-11-11Clinical Trial Update: Linking Hospitalized Injection Drug Users to Buprenorphine [Phase 3]
Phase 3 clinical trial completion investigating buprenorphine for opioid use disorder in hospitalized injection drug users.
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CLINICAL_TRIALS trial_result · 2015-10-22Clinical Trial Update: Pre-Release VIVITROL for Opioid Dependent Inmates [Phase 4]
Phase 4 trial update evaluating VIVITROL for opioid dependence. The study conducted at Rhode Island Hospital has been completed.
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CLINICAL_TRIALS trial_result · 2015-10-15Clinical Trial Update: Effects of Diacetylmorphine (DAM) on Brain Function and Stress Response [Phase 1]
Phase 1 study evaluating the effects of diacetylmorphine on brain function and stress response; the trial has completed.
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CLINICAL_TRIALS trial_result · 2015-09-25Clinical Trial Update: Yoga for Pain and Opioid Dependence [Phase 1, Phase 2]
This clinical trial update indicates completed Phase 1 and Phase 2 studies evaluating yoga as an intervention for chronic pain and opioid us…
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CLINICAL_TRIALS trial_result · 2015-09-17Clinical Trial Update: Comparison of Two Counseling Induction Strategies [NA]
A completed clinical trial comparing two counseling induction strategies for starting methadone treatment in individuals with opioid use dis…
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CLINICAL_TRIALS trial_result · 2015-09-04Clinical Trial Update: An Open-label Study of Oral Paliparidone for the Treatment of Patients With Co-occurring Opioid and ATS Dependence [Phase 3]
An open-label Phase 3 trial evaluating paliparidone for co-occurring opioid use disorder (heroin dependence) and amphetamine use disorder; c…
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CLINICAL_TRIALS trial_result · 2015-08-28Clinical Trial Update: Lofexidine for Inpatient Opiate Detox in Singapore [Phase 4]
The clinical trial update indicates a Phase 4 study of lofexidine for inpatient detoxification in opioid-dependent patients in Singapore has…
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CLINICAL_TRIALS trial_result · 2015-08-05Clinical Trial Update: RCT Comparing Methadone and Buprenorphine in Pregnant Women [Phase 3]
Phase 3 randomized trial comparing methadone and buprenorphine in pregnant women with opioid use disorder; results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-07-24Clinical Trial Update: Integration of Buprenorphine Into HIV Clinical Settings - Primary Care Model (PCM) [Phase 4]
Phase 4 trial update evaluating the integration of buprenorphine treatment into HIV primary care settings to manage opioid use disorder in p…
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CLINICAL_TRIALS trial_result · 2015-06-03Clinical Trial Update: Combined Buprenorphine and Behavioral Treatment With and Without Contingent Reinforcement on Opioid and Cocaine Abstinence. - 22 [Phase 2]
A Phase 2 study evaluated whether adding contingent reinforcement to buprenorphine-based behavioral treatment improves opioid and cocaine ab…
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CLINICAL_TRIALS trial_result · 2015-05-28Clinical Trial Update: Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide - 2 [Phase 2]
Phase 2 trial evaluating whether cold water immersion modulates the reinforcing effects of nitrous oxide in individuals with opioid use diso…
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CLINICAL_TRIALS trial_result · 2015-05-28Clinical Trial Update: Lack of Acute Tolerance Development to Effects of Nitrous Oxide - 4 [Phase 2]
The Phase 2 clinical trial found no evidence of acute tolerance to the effects of nitrous oxide in participants with opioid-related and subs…
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CLINICAL_TRIALS trial_result · 2015-05-28Clinical Trial Update: Effects of Subanesthetic Concentrations of Nitrous Oxide - 1 [Phase 2]
A Phase 2 trial evaluating subanesthetic concentrations of nitrous oxide for opioid use disorder and other substance-related disorders has c…
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CLINICAL_TRIALS trial_result · 2015-05-28Clinical Trial Update: Differential Acute Tolerance Development to Effects of Nitrous Oxide - 7 [Phase 2]
A Phase 2 clinical trial investigating differential acute tolerance to the effects of nitrous oxide in individuals with opioid use disorder …
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CLINICAL_TRIALS trial_result · 2015-05-28Clinical Trial Update: Models of Screening, Brief Intervention With a Facilitated Referral to Treatment (SBIRT) for Opioid Patients in the Emergency Department [NA]
A completed clinical trial evaluating SBIRT with facilitated referral to treatment for opioid patients in the emergency department; results …
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CLINICAL_TRIALS trial_result · 2015-05-28Clinical Trial Update: Effects of Alcohol History on Effects of Nitrous Oxide - 9 [NA]
This clinical trial update reports completed results on how a history of alcohol use affects the effects of nitrous oxide.
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CLINICAL_TRIALS trial_result · 2015-05-28Clinical Trial Update: Phone Interview to Prevent Recurring Opioid Overdoses [NA]
Completed clinical trial assessing a phone interview intervention to prevent recurrent opioid overdoses.
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CLINICAL_TRIALS trial_result · 2015-05-28Clinical Trial Update: Effects of Nitrous Oxide: A Dose-Response Analysis - 5 [NA]
This completed clinical trial update analyzes the dose-response effects of nitrous oxide in individuals with opioid use disorder and other s…