Opioid Use Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-01-06Clinical Trial Update: Starting Treatment With Agonist Replacement Therapies (START) [Phase 4]
The START Phase 4 trial, conducted at UCLA, reports results from initiating agonist replacement therapies for opioid use disorder.
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CLINICAL_TRIALS trial_result · 2016-12-26Clinical Trial Update: Single Ascending Dose Study of RBP-6000 [Phase 1]
Phase 1 single ascending dose study of RBP-6000 for opioid use disorder has completed, providing early safety and pharmacokinetic data. The …
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CLINICAL_TRIALS trial_result · 2016-12-06Clinical Trial Update: A Drug Treatment for Cocaine Users Who Are Also on Methadone Maintenance Treatment [NA]
This clinical trial update involves a drug treatment for individuals with cocaine dependence who are on methadone maintenance; the study was…
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CLINICAL_TRIALS trial_result · 2016-12-05Clinical Trial Update: Abuse Liability of Suboxone Versus Subutex [Phase 3]
Phase 3 trial comparing the abuse liability of Suboxone (buprenorphine/naloxone) versus Subutex (buprenorphine) in opioid-related disorders;…
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CLINICAL_TRIALS trial_result · 2016-12-05Clinical Trial Update: Phase IIa Study of AV411, a Glial Activation Inhibitor, for Opioid Withdrawal [Phase 2]
Phase IIa study of AV411 (ibudilast), a glial activation inhibitor, for opioid withdrawal has completed with results posted.
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CLINICAL_TRIALS trial_result · 2016-11-30Clinical Trial Update: FMRI of Stress and Addictive Disorders
A completed Yale University study used functional MRI to examine brain responses to stress in individuals with cocaine use disorder, opioid …
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CLINICAL_TRIALS trial_result · 2016-11-07Clinical Trial Update: Clinical Rescue Protocol - 2 [Phase 2]
A Phase 2 clinical trial on opioid use disorder conducted by UCLA has completed.
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CLINICAL_TRIALS trial_result · 2016-10-26Clinical Trial Update: Methylnaltrexone Pharmacokinetics in Neurointensive Care Patients [Phase 1]
Phase 1 pharmacokinetic study of methylnaltrexone in neurointensive care patients has completed.
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CLINICAL_TRIALS trial_result · 2016-09-30Clinical Trial Update: Evaluation of Changes in Prescribing Behavior of ER/LA Opioid Prescribers
Clinical trial update evaluating changes in prescribing behavior of extended-release/long-acting opioid prescribers. The current status of t…
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CLINICAL_TRIALS trial_result · 2016-09-08Clinical Trial Update: Conflict Between Maternal Autonomy and Child Health in Substance-use
This completed clinical trial update examines the balance between maternal autonomy and neonatal health in the setting of substance use duri…
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CLINICAL_TRIALS trial_result · 2016-08-17Clinical Trial Update: Efficacy of Drug and Risk Counseling Among Methadone Patients in Jakarta, Indonesia [Phase 2]
Phase 2 trial evaluating the efficacy of an unspecified drug plus risk counseling in methadone-maintained patients in Jakarta, with outcomes…
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: Buprenorphine Maintenance Protocol - 1 [Phase 3]
Phase 3 trial of a buprenorphine maintenance protocol for opioid use disorder has completed.
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: Influence of Dexmedetomidine and Lidocaine on Opioid Consumption in Laparoscopic Intestine Resection [Phase 4]
Phase 4 trial update assessing whether dexmedetomidine and lidocaine reduce postoperative opioid consumption in patients undergoing laparosc…
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: Multicenter Clinical Trial of Buprenorphine - 3 [Phase 3]
Phase 3 clinical trial of buprenorphine for opioid use disorder has completed.
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CLINICAL_TRIALS trial_result · 2016-06-27Clinical Trial Update: Opioid Analgesic Use and Disposal Following Outpatient Dental Surgery [NA]
A completed clinical trial update from the University of Pennsylvania examining opioid analgesic use and disposal after outpatient dental su…
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CLINICAL_TRIALS trial_result · 2016-06-01Clinical Trial Update: Low Dose Naltrexone-buprenorphine Transfer to Vivitrol Injection in Opioid Dependence [Phase 2]
A Phase 2 trial evaluated transitioning opioid-dependent patients from low-dose naltrexone-buprenorphine to extended-release naltrexone (Viv…
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CLINICAL_TRIALS trial_result · 2016-05-16Clinical Trial Update: Study to Assess Pharmacokinetic (PK), Bioavailability & Food Effect of MR902 Compared With Immediate Release (IR) Morphine Sulphate Oral Solution [Phase 1]
Phase 1 clinical trial to assess the pharmacokinetics, bioavailability, and food effect of MR902 compared with immediate-release morphine su…
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CLINICAL_TRIALS trial_result · 2016-05-09Clinical Trial Update: Single-dose, Study of RBP-6000 in Opioid Dependent Individuals [Phase 1]
Phase 1 single-dose study of RBP-6000 for opioid use disorder has completed.
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CLINICAL_TRIALS trial_result · 2016-05-06Clinical Trial Update: Alternate Day Buprenorphine Administration, Phase XI - 16 [Phase 2]
The document reports the completion of a Phase 2 trial evaluating alternate-day buprenorphine administration for opioid-related disorders.
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CLINICAL_TRIALS trial_result · 2016-05-06Clinical Trial Update: Buprenorphine Detoxification With Two Types of Treatment. BBD III - 12 [Phase 2]
Phase 2 clinical trial evaluating buprenorphine detoxification using two treatment approaches for opioid use disorder; study completed.
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CLINICAL_TRIALS trial_result · 2016-05-06Clinical Trial Update: Buprenorphine Detox With Two Types of Treatment. BBD II - 11 [Phase 2]
Phase 2 trial evaluating buprenorphine detoxification with two treatment approaches for opioid use disorder has completed.
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CLINICAL_TRIALS trial_result · 2016-05-06Clinical Trial Update: Alternate-Day Buprenorphine Administration. Phase VIII - 9 [Phase 2]
A Phase 2 trial evaluating alternate-day buprenorphine administration for opioid use disorder has completed.
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CLINICAL_TRIALS trial_result · 2016-05-06Clinical Trial Update: Buprenorphine Dose Alteration Study - 1 [Phase 1]
Phase 1 clinical trial evaluating dosing adjustments of buprenorphine for opioid use disorder has completed, conducted by the University of …
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CLINICAL_TRIALS trial_result · 2016-05-06Clinical Trial Update: Neurobiology of Opioid Dependence: 4 - 4 [Phase 2]
Phase 2 clinical trial on the neurobiology of opioid dependence sponsored by Yale University has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-05-02Clinical Trial Update: Study to Evaluate the Subjective Effects of PTI-801 in Non-Physically Dependent Subjects With a History of Drug Abuse [Phase 2]
Phase 2 trial evaluating the subjective effects of PTI-801 in individuals with a history of opioid-related disorders; the study status is co…