Opioid Use Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-03-23Clinical Trial Update: Nasal Human Abuse Potential of PTI-821 [Phase 1]
A Phase 1 clinical trial update reports results on the nasal abuse potential of PTI-821 in nondependent opioid users.
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CLINICAL_TRIALS trial_result · 2018-03-09Clinical Trial Update: Comparison of Naloxone Pharmacokinetics [Phase 1]
Phase 1 study comparing naloxone pharmacokinetics in individuals with opioid use disorder has completed.
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CLINICAL_TRIALS trial_result · 2018-01-19Clinical Trial Update: Extended-Release Naltrexone vs. Buprenorphine for Opioid Treatment [Phase 4]
Phase 4 trial comparing extended-release naltrexone to buprenorphine for opioid use disorder has completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2017-12-26Clinical Trial Update: Employment-Based Depot Naltrexone Clinical Trial II [Phase 2]
Phase 2 clinical trial update for employment-based depot naltrexone in opiate dependence; study completed with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-12-07Clinical Trial Update: Cognitive Function and Addiction Under Opioid Tapering [Phase 3]
Phase 3 clinical trial update on cognitive function and addiction during opioid tapering in adults with chronic pain and opioid use disorder…
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CLINICAL_TRIALS trial_result · 2017-12-05Clinical Trial Update: Efficacy of Acupuncture as an Adjunct to Methadone Treatment Services for Heroin Addicts [NA]
This clinical trial evaluates acupuncture as an adjunct to methadone treatment for heroin addiction, focusing on opioid withdrawal symptoms …
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Pilot Study of Contingency Management for Smoking Cessation [NA]
A pilot clinical trial evaluating contingency management for smoking cessation has completed.
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CLINICAL_TRIALS trial_result · 2017-11-21Clinical Trial Update: Neonatal and Maternal Effects of Buprenorphine and Methadone
This trial evaluated neonatal and maternal outcomes of buprenorphine versus methadone treatment in opioid-maintained pregnant women. The stu…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Functional Magnetic Resonance Imaging of Opioid Withdrawal in Healthy Human Volunteers [NA]
A Stanford functional MRI study investigated brain activity during opioid withdrawal in healthy volunteers; the trial is completed and resul…
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CLINICAL_TRIALS trial_result · 2017-11-01Clinical Trial Update: Feasibility Study of Take-Home LAAM Medication - 3 [Phase 4]
A Phase 4 feasibility trial testing take-home LAAM for opioid-related disorders has completed.
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Study to Evaluate the Exposures of Lofexidine and Its Major Metabolites in Subjects Seeking Buprenorphine Dose Reduction [Phase 1]
A Phase 1 clinical trial update evaluating the exposures of lofexidine and its major metabolites in subjects seeking buprenorphine dose redu…
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CLINICAL_TRIALS trial_result · 2017-10-23Clinical Trial Update: Treatment Study Using Depot Naltrexone (1/6) Philadelphia Coord/Data Mgmt Site [Phase 2, Phase 3]
Completed Phase 2/3 trial evaluating depot naltrexone for opioid addiction; results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-10-17Clinical Trial Update: The Discriminative Effects of Tramadol in Humans [Phase 1, Phase 2]
Phase 1 and Phase 2 studies explored the discriminative effects of tramadol in humans for opioid use disorder and stimulant use disorder; re…
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CLINICAL_TRIALS trial_result · 2017-10-17Clinical Trial Update: Sex and Female Empowerment [NA]
This clinical trial update notes the completion of a study sponsored by the University of North Carolina focusing on sex and female empowerm…
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CLINICAL_TRIALS trial_result · 2017-09-26Clinical Trial Update: Evaluation of a Computerized Opioid Overdose Prevention Program [NA]
This clinical trial update reports completion and posted results of a study evaluating a computerized opioid overdose prevention program, co…
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CLINICAL_TRIALS trial_result · 2017-09-20Clinical Trial Update: Investigation of the Effect of Intravenous Lidocaine Infusion on Postoperative Pain Treatment and Bowel Function in Robotic Bowel Surgery [Phase 4]
Phase 4 clinical trial investigating intravenous lidocaine infusion for postoperative pain and bowel function after robotic bowel surgery.
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CLINICAL_TRIALS trial_result · 2017-08-17Clinical Trial Update: Effects of Ibudilast on Oxycodone Self-administration in Opioid Abusers [Phase 2]
Phase 2 trial assessing the effect of ibudilast on oxycodone self-administration in individuals with opioid use disorder; study completed wi…
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CLINICAL_TRIALS trial_result · 2017-07-07Clinical Trial Update: Prescription Opioid Effects in Abusers Versus Non-Abusers [Phase 2]
A Phase 2 study compares the effects of prescription opioids in abusers versus non-abusers. Results have been posted.
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CLINICAL_TRIALS trial_result · 2017-07-06Clinical Trial Update: Medications Development for Drug Abuse Disorders [Phase 1, Phase 2]
This update reports completed Phase 1 and Phase 2 trials of medications for opioid use disorder, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-07-05Clinical Trial Update: A Laboratory Model for Heroin Abuse Medications - 8 [Phase 2]
Phase 2 clinical trial update on a laboratory model for heroin abuse medications has completed. Sponsored by the New York State Psychiatric …
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CLINICAL_TRIALS trial_result · 2017-06-29Clinical Trial Update: The Effectiveness of Deep Brain Stimulation for Opioid Relapse Prevention [Phase 2, Phase 3]
This clinical trial update discusses the effectiveness of deep brain stimulation for preventing relapse in opioid use disorder, covering Pha…
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CLINICAL_TRIALS trial_result · 2017-06-12Clinical Trial Update: Testosterone Replacement for Male Opioid Agonist Maintained Patients [Phase 1, Phase 2]
Phase 1/Phase 2 trial evaluating testosterone replacement in men on opioid agonist therapy with chronic pain and symptomatic hypogonadism; r…
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CLINICAL_TRIALS trial_result · 2017-06-05Clinical Trial Update: Clomiphene Citrate for the Treatment of Low Testosterone Associated With Chronic Opioid Pain Medication Administration [Phase 2]
Phase 2 clinical trial update evaluating clomiphene citrate for treating low testosterone in men on chronic opioid therapy; the study comple…
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CLINICAL_TRIALS trial_result · 2017-06-05Clinical Trial Update: Palonosetron and Hydroxyzine to Reduce Opioid Withdrawal [NA]
A completed clinical trial evaluated the combination of palonosetron and hydroxyzine to reduce opioid withdrawal symptoms; results have been…
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CLINICAL_TRIALS trial_result · 2017-06-02Clinical Trial Update: Buprenorphine in the Emergency Department [Phase 4]
A Phase 4 clinical trial evaluating buprenorphine in the emergency department for opioid withdrawal and opioid-use disorder has completed.