Open-angle Glaucoma
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Sign up freeTop drugs studied for this disease
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FDA approval · 2024-09-16FDA Approved: TIMOLOL MALEATE — Original Application (Somerset Therapeutics, LLC)
FDA approved the original application for TIMOLOL MALEATE (generic) by Somerset Therapeutics, LLC, for ophthalmic use to treat elevated intr…
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FDA approval · 2024-09-10FDA Approved: BRIMONIDINE TARTRATE AND TIMOLOL MALEATE — Original Application (Somerset Therapeutics, LLC)
FDA approved a new original application for a fixed-dose combination eye drop of brimonidine tartrate and timolol maleate for lowering intra…
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Safety of Topical Insulin Drops for Open-angle Glaucoma [Phase 1]
A Phase 1 study assesses the safety of topical insulin eye drops for open-angle glaucoma, with status currently ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS research · 2024-08-15Clinical Trial Update: Clinical Study of Glaukos® Trabecular Micro-Bypass System Model iS3 Infinite Vs. Competitor [NA]
An ongoing clinical trial compares the Glaukos Trabecular Micro-Bypass System iS3 Infinite against a competitor for open-angle glaucoma and …
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CLINICAL_TRIALS trial_result · 2024-08-14Clinical Trial Update: Study of OMNI System in OAG (GEMINI) [NA]
The GEMINI trial evaluating the OMNI System for open-angle glaucoma has completed. Results have been posted on 2024-08-14.
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FDA approval · 2024-08-09FDA Approved: BRIMONIDINE TARTRATE — Original Application (Somerset Therapeutics, LLC)
The FDA approved the original application for Brimonidine Tartrate, a generic ophthalmic solution, enabling its sale for lowering intraocula…
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FDA approval · 2024-08-07FDA Approved: TRAVOPROST OPHTHALMIC SOLUTION, 0.004% — Supplemental Application (Mylan Pharmaceuticals Inc.)
FDA approved a supplemental application for Travoprost Ophthalmic Solution 0.004% from Mylan, establishing a generic version of travoprost f…
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FDA approval · 2024-08-07FDA Approved: TIMOLOL MALEATE — Original Application (Caplin Steriles Limited)
FDA approved Caplin Steriles Limited's original ANDA for Timolol Maleate, a generic eye drop product.
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Safety and Effectiveness of Minimally Invasive Micro Sclerostomy (MIMS®) to Reduce Intraocular Pressure in Open-Angle Glaucoma Which is Not Controlled Despite Polypharmacy [NA]
An update on a clinical trial evaluating the Minimally Invasive Micro Sclerostomy (MIMS) procedure to reduce intraocular pressure in primary…
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CLINICAL_TRIALS research · 2024-08-06Clinical Trial Update: A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes [Phase 1]
Clinical trial update for a Phase 1 bioequivalence study in open-angle glaucoma and ocular hypertension, currently recruiting.
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CLINICAL_TRIALS research · 2024-07-30Clinical Trial Update: A Study of AMDX-2011P in Participants With Primary Open Angle Glaucoma [Phase 2]
A Phase 2 clinical trial update indicates AMDX-2011P for primary open-angle glaucoma is currently recruiting.
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CLINICAL_TRIALS research · 2024-07-29Clinical Trial Update: The Objective is to Evaluate the Anterior Chamber Angle After BANG Procedure, the Study Will Recruit 12 Patients Who Will Undergo Planned Goniectomy for Uncontrolled POAG, Anterior Segment OCT Scan Will Be Used to Evaluate the Anterior Chamber Postoperatively.
This clinical trial will recruit 12 patients with uncontrolled primary open-angle glaucoma to evaluate the anterior chamber angle after the …
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FDA approval · 2024-07-25FDA Approved: ISTALOL — Supplemental Application (Bausch & Lomb Incorporated)
The FDA approved a supplemental application for ISTALOL (timolol maleate) submitted by Bausch & Lomb Incorporated.
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: Regulation of Intraocular Pressure in Glaucoma Patients by Acupressure [NA]
This completed clinical trial assessed whether acupressure can regulate intraocular pressure in patients with primary open-angle glaucoma. T…
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Impact of Timolol/Dorzolamide Therapy on Autoregulation in Glaucoma Patients [Phase 4]
Phase 4 trial evaluating the impact of a fixed-dose Timolol/Dorzolamide therapy on ocular autoregulation in open-angle glaucoma patients has…
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CLINICAL_TRIALS trial_result · 2024-07-15Clinical Trial Update: A Long Term Study of STN1012600 in Subjects With Open Angle Glaucoma or Ocular Hypertension [Phase 3]
The document reports that the long-term Phase 3 study of STN1012600 in open-angle glaucoma or ocular hypertension has completed.
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CLINICAL_TRIALS research · 2024-07-12Clinical Trial Update: Efficacy of NSAID vs. Steroid-NSAID Combo Post-Selective Laser Trabeculoplasty: Phase 4, Single-Center RCT [Phase 4]
Phase 4 trial comparing NSAID alone versus a steroid-NSAID combination to manage postoperative inflammation after selective laser trabeculop…
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Culturing TM Cells From Primary Open-angle Glaucoma Patient Biopsies
The trial reports on culturing trabecular meshwork cells from biopsies of patients with primary open-angle glaucoma; the study has completed…
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CLINICAL_TRIALS research · 2024-06-24Clinical Trial Update: CRISPR/Cas9 Instantaneous Gene Editing Therapy to Intraocular Hypertensive POAG With MYOC Mutation [NA]
A CRISPR/Cas9 instantaneous gene editing therapy for MYOC-mutant primary open-angle glaucoma is in a clinical trial and currently recruiting…
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: Comparing Hydrus Microstent(TM) to the iStent for Lowering IOP in Glaucoma Patients Undergoing Cataract Surgery [NA]
A completed clinical trial compared the Hydrus Microstent to the iStent for lowering intraocular pressure in glaucoma patients undergoing ca…
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: The Heidelberg Engineering ANTERION Anterior Segment Metrics Precision and Agreement Study
Completed study assessing the precision and agreement of the ANTERION anterior segment metrics for imaging in open-angle and angle-closure g…
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CLINICAL_TRIALS research · 2024-06-12Clinical Trial Update: The A D A G I O Study
Update on the ADAGIO Study indicating the trial is not yet recruiting for open-angle glaucoma and ocular hypertension.
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: Travoprost Intraocular Implant in Conjunction With Cataract Surgery [Phase 3]
A Phase 3 trial update for a travoprost intraocular implant used during cataract surgery for open-angle glaucoma and ocular hypertension; th…
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CLINICAL_TRIALS trial_result · 2024-05-30Clinical Trial Update: Social History and Glaucoma Progression
A completed clinical trial from Assiut University investigating social history and its relation to progression in open-angle glaucoma.
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CLINICAL_TRIALS trial_result · 2024-05-30Clinical Trial Update: PASCAL Trabeculoplasty [NA]
A clinical trial of PASCAL trabeculoplasty for open-angle glaucoma has been terminated.