Open-angle Glaucoma
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: OPC-1085EL in the Treatment of Primary Open Angle Glaucoma or Ocular Hypertension in Chinese Subjects [Phase 3]
This document reports the completion of Phase 3 trials of OPC-1085EL for primary open-angle glaucoma and ocular hypertension in Chinese subj…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT) [Phase 2]
Phase 2 study evaluating the efficacy and safety of the OTX-TIC travoprost intracameral implant for Open Angle Glaucoma or Ocular Hypertensi…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: A Real-World Evidence Study of Goniotomy With the C-REX™ Instrument in Patients With Primary Open Angle Glaucoma
This clinical trials update outlines a real-world evidence study evaluating goniotomy using the C-REX instrument in patients with primary op…
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: Efficacy and Safety of Gonioscopy Assisted Transluminal Trabeculotomy in Patients with Primary Open-angle Glaucoma and Cataract. [NA]
This clinical trial update describes the ongoing assessment of Gonioscopy Assisted Transluminal Trabeculotomy (GATT) for patients with prima…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: PRO-122 Versus Concomitant Therapy in Subjects With Uncontrolled Primary Open-angle Glaucoma (PRO-122LATAM) [Phase 3]
Phase 3 trial PRO-122LATAM assessing PRO-122 versus concomitant therapy in uncontrolled primary open-angle glaucoma has been terminated.
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: STAR-LIFE: a Post-market Registry on MINIject
STAR-LIFE is a post-market registry evaluating MINIject for open-angle glaucoma, currently recruiting.
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: A Phase III Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension in China [Phase 3]
Phase III clinical trial in China evaluating a treatment for open-angle glaucoma or ocular hypertension is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: MINIject Implantation Combined With Cataract Surgery in Patients With POAG and Cataract [NA]
Clinical trial update indicates MINIject implantation combined with cataract surgery for primary open-angle glaucoma and cataract is current…
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: MINIject Global Long-Term Follow-up Study
This is a global long-term follow-up study for the MINIject glaucoma implant, sponsored by iSTAR Medical, in open-angle glaucoma and ocular …
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CLINICAL_TRIALS research · 2025-02-26Clinical Trial Update: Multimodal Morpho-functional Study in Glaucoma Patients-Citicoline Oral Solution [NA]
Ongoing multimodal morpho-functional study evaluating citicoline oral solution in patients with primary open-angle glaucoma; the trial is cu…
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FDA approval · 2025-02-25FDA Approved: BRIMONIDINE TARTRATE/TIMOLOL MALEATE OPHTHALMIC SOLUTION — Original Application (Leading Pharma, LLC)
FDA approved a generic fixed-dose combination ophthalmic solution of brimonidine tartrate and timolol maleate from Leading Pharma, LLC under…
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FDA approval · 2025-02-18FDA Approved: DORZOLAMIDE HYDROCHLORIDE AND TIMOLOL MALEATE — Original Application (Genus Lifesciences)
FDA approved the original application for a generic dorzolamide hydrochloride and timolol maleate combination to treat elevated intraocular …
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Open-Label Study of Safety of H1337 in Healthy Volunteers [Phase 1]
Open-label Phase 1 safety study of H1337 in healthy volunteers completed; Open-angle glaucoma and ocular hypertension are listed as the stud…
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FDA approval · 2025-02-11FDA Approved: DORZOLAMIDE HYDROCHLORIDE — Original Application (Somerset Therapeutics, LLC)
FDA approved a generic dorzolamide hydrochloride product under an Original Application by Somerset Therapeutics, LLC. Dorzolamide hydrochlor…
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CLINICAL_TRIALS research · 2025-02-10Clinical Trial Update: Expanded Access to Bimatoprost (Durysta)
Expanded access to the Durysta bimatoprost implant for open-angle glaucoma is updated, noting that the program is no longer available.
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: A Prospective Interventional Cohort Study to Evaluate the Efficacy and Safety of the AquaLumen, a Novel Filtration Procedure for the Treatment of Open Angle Glaucoma [NA]
A prospective interventional cohort study is planned to evaluate the efficacy and safety of AquaLumen, a novel filtration procedure, for ope…
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CLINICAL_TRIALS research · 2025-02-04Clinical Trial Update: Dresden Glaucoma and Treatment Study (DGTS)
The Dresden Glaucoma and Treatment Study (DGTS) is currently recruiting to evaluate treatments for multiple forms of glaucoma, including ope…
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: A Clinical Trial Comparing the OMNI Surgical System to Standard Medical Treatment in Patients With Primary Open Angle Glaucoma [Phase 4]
A Phase 4 trial comparing the OMNI Surgical System to standard medical therapy for primary open-angle glaucoma was terminated.
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: Performance and Safety of the ARGOS-SC Suprachoroidal Pressure Sensor in Patients With Glaucoma Undergoing Non-penetrating Glaucoma Surgery [NA]
Results from a completed clinical trial evaluating the performance and safety of the ARGOS-SC Suprachoroidal Pressure Sensor in glaucoma pat…
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CLINICAL_TRIALS research · 2025-01-24Clinical Trial Update: A Study Investigating Oral Semaglutide in People with Open-Angle Glaucoma [Phase 4]
This is an ongoing Phase 4 clinical trial evaluating oral semaglutide in people with open-angle glaucoma. The study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-01-20Clinical Trial Update: Qlaris Phase 2 Study of QLS-111 in POAG And/or OHT Patients [Phase 2]
This notice reports the completion of a Phase 2 study evaluating QLS-111 in patients with primary open-angle glaucoma and ocular hypertensio…
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CLINICAL_TRIALS trial_result · 2025-01-20Clinical Trial Update: Qlaris Study of QLS-111 in Combination With a PGA for OAG and/or OHT Patients [Phase 2]
Phase 2 clinical trial update for QLS-111 in combination with a prostaglandin analogue for open-angle glaucoma and ocular hypertension; the …
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CLINICAL_TRIALS trial_result · 2025-01-17Clinical Trial Update: Study to Evaluate QLS-101 Compared to Timolol Maleate Eye Drops in Subjects With High Eye Pressure (Glaucoma or Ocular Hypertension). [Phase 2]
A Phase 2 trial comparing QLS-101 to Timolol Maleate Eye Drops in adults with high eye pressure due to primary open-angle glaucoma or ocular…
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CLINICAL_TRIALS trial_result · 2025-01-15Clinical Trial Update: Safety and Effectiveness of the Hydrus Microstent [NA]
A clinical trial update indicates safety and effectiveness data for the Hydrus Microstent in open-angle glaucomas, but the study has been te…
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CLINICAL_TRIALS trial_result · 2025-01-10Clinical Trial Update: Minimally Invasive Nasal Trabeculostomy: Long-Term Follow-Up Extension Study
Long-term follow-up extension study of minimally invasive nasal trabeculostomy for open-angle glaucoma has completed.