Open-angle Glaucoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-01-12Clinical Trial Update: Intraocular Pressure, Blood Pressure, Ocular Perfusion and Blood Flow Fluctuations in Glaucoma Patients
This completed clinical trial update investigates fluctuations in intraocular pressure, blood pressure, ocular perfusion, and ocular blood f…
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CLINICAL_TRIALS trial_result · 2012-01-06Clinical Trial Update: Safety and Efficacy Study of Bimatoprost, Latanoprost, and Travoprost in Patients With Elevated Intraocular Pressure (IOP) and Open-angle Glaucoma (OAG)
This clinical trial update reports on the safety and efficacy of bimatoprost, latanoprost, and travoprost in patients with elevated intraocu…
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CLINICAL_TRIALS trial_result · 2011-11-24Clinical Trial Update: 24-hour IOP-lowering Effect of Brimonidine 0.1% [Phase 4]
A Phase 4 trial assessing the 24-hour intraocular pressure-lowering effect of brimonidine 0.1% in open-angle glaucoma and ocular hypertensio…
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CLINICAL_TRIALS trial_result · 2011-11-03Clinical Trial Update: Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-angle Glaucoma or Ocular Hypertension [Phase 2]
Phase 2 study of DE-104 ophthalmic solution for open-angle glaucoma or ocular hypertension has completed, reporting safety and efficacy resu…
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CLINICAL_TRIALS trial_result · 2011-11-03Clinical Trial Update: Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-angle Glaucoma or Ocular Hypertension [Phase 1, Phase 2]
The safety and efficacy study of DE-104 ophthalmic solution for open-angle glaucoma or ocular hypertension has completed Phase 1 and Phase 2…
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CLINICAL_TRIALS trial_result · 2011-10-31Clinical Trial Update: Evaluation of Hyperemia With the Use of Ocular Prostaglandin Analogues [Phase 4]
Phase 4 trial evaluating hyperemia with ocular prostaglandin analogues in open angle glaucoma and ocular hypertension; results posted in 201…
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FDA approval · 2011-09-30FDA Approved: TIMOPTIC IN OCUDOSE — Supplemental Application (Bausch & Lomb Incorporated)
The FDA approved a supplemental application for TIMOPTIC IN OCUDOSE (timolol maleate) submitted by Bausch & Lomb Incorporated.
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FDA approval · 2011-09-30FDA Approved: TIMOPTIC-XE — Supplemental Application (Bausch & Lomb Incorporated)
FDA approved a supplemental application for TIMOPTIC-XE (timolol maleate) from Bausch & Lomb, reflecting an approved update to the product's…
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CLINICAL_TRIALS trial_result · 2011-09-13Clinical Trial Update: Preservative-Free MK2452 (Tafluprost) for Open-Angle Glaucoma/Ocular Hypertension (MK2452-001)(COMPLETED) [Phase 3]
The Phase 3 study MK2452-001 evaluating preservative-free tafluprost for open-angle glaucoma and ocular hypertension has completed, with res…
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FDA label_change · 2011-09-07FDA Approved: TRAVATAN Z — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA approved a supplemental application for TRAVATAN Z (travoprost) submitted by Novartis Pharmaceuticals, updating the product labeling…
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CLINICAL_TRIALS trial_result · 2011-08-03Clinical Trial Update: 24h Continuous Intraocular Pressure (IOP) Monitoring vs Goldmann Applanation Tonometry
A completed clinical trial comparing 24-hour continuous intraocular pressure monitoring versus Goldmann applanation tonometry in Primary Ope…
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CLINICAL_TRIALS trial_result · 2011-07-08Clinical Trial Update: A Study of Ganfort Versus Duotrav in Patients With Primary Open Angle Glaucoma or Ocular Hypertension [Phase 3]
A Phase 3 study comparing Ganfort versus Duotrav in patients with primary open-angle glaucoma or ocular hypertension has completed.
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CLINICAL_TRIALS research · 2011-06-27Clinical Trial Update: Normal Tension and Chronic Open Angle Glaucoma and Cerebrospinal Fluid Composition [NA]
This clinical trial update covers study NCT00306657 investigating normal tension glaucoma and chronic open-angle glaucoma with analysis of c…
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CLINICAL_TRIALS trial_result · 2011-06-23Clinical Trial Update: Travoprost Five Day Posology Study [Phase 2]
Phase 2 clinical trial update evaluating five-day posology of travoprost in open-angle glaucoma and ocular hypertension. The study results w…
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CLINICAL_TRIALS research · 2011-06-23Clinical Trial Update: Relationship Between Central Corneal Thickness and Intraocular Pressure Measures Instruments.
A completed clinical trial examining how central corneal thickness affects intraocular pressure measurements across different instruments in…
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CLINICAL_TRIALS other · 2011-06-08Clinical Trial Update: Evaluation of OT-135P (IOPtiMateTM) : Beam Manipulating System for CO2 Laser Assisted Non-Penetrating Glaucoma Surgery [NA]
Clinical trial update evaluating the OT-135P (IOPtiMate) beam‑manipulating system for CO2 laser assisted non-penetrating glaucoma surgery. S…
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CLINICAL_TRIALS research · 2011-05-09Clinical Trial Update: Comparative Study of Ologen Collagen Matrix Versus Mitomycin-C in Trabeculectomy: A Study in Germany [NA]
This study in Germany compares Ologen Collagen Matrix with Mitomycin-C in trabeculectomy for open-angle glaucoma.
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CLINICAL_TRIALS research · 2011-05-03Clinical Trial Update: a 3.0T Magnetic Resonance Imaging Study
This document provides an update on a 3.0 Tesla MRI study related to Primary open-angle glaucoma.
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CLINICAL_TRIALS trial_result · 2011-04-01Clinical Trial Update: A Prospective, Multicenter, Open-label, Safety and Preliminary Efficacy Study of the Surgical Implantation of OPKO's Glaucoma Drainage Device (AquashuntTM) in Patients With Refractory Chronic Forms of Open Angle Glaucoma (OAG) [NA]
A prospective, multicenter open-label study evaluated the safety and preliminary efficacy of surgically implanting OPKO's Aquashunt glaucoma…
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CLINICAL_TRIALS trial_result · 2011-03-25Clinical Trial Update: A 6 Month Study Comparing Latanoprost With Timolol in Patients With Open Angle Glaucoma or Ocular Hypertension [Phase 3]
A Phase 3 trial comparing latanoprost with timolol in open-angle glaucoma and ocular hypertension has completed.
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FDA approval · 2011-03-22FDA Approved: LATANOPROST — Original Application (Sandoz Inc)
FDA approves the generic latanoprost (Sandoz) under Original Application (ANDA). The product is indicated for reduction of elevated intraocu…
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FDA approval · 2011-03-22FDA Approved: LATANOPROST — Original Application (Somerset Therapeutics, LLC)
FDA approved the original application for latanoprost from Somerset Therapeutics, enabling a generic latanoprost ophthalmic solution for red…
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FDA approval · 2011-03-08FDA Approved: BRINZOLAMIDE — Supplemental Application (Sandoz Inc)
The FDA approved a supplemental application for brinzolamide submitted by Sandoz Inc.
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CLINICAL_TRIALS trial_result · 2011-03-08Clinical Trial Update: Efficacy Study of Travoprost APS Versus TRAVATAN [Phase 3]
Phase 3 efficacy trial comparing Travoprost APS with TRAVATAN in open-angle glaucoma and ocular hypertension; results were posted after comp…
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FDA approval · 2011-01-28FDA Approved: DORZOLAMIDE HYDROCHLORIDE — Supplemental Application (Advagen Pharma Ltd.)
FDA approved a supplemental application for dorzolamide hydrochloride from Advagen Pharma Ltd., a generic product used to treat open-angle g…