Open-angle Glaucoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-04-07Clinical Trial Update: Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID Plus Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension [Phase 3]
Phase 3 trial comparing brinzolamide/brimonidine fixed combination given twice daily versus separate brinzolamide and brimonidine in open-an…
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CLINICAL_TRIALS trial_result · 2014-04-04Clinical Trial Update: Safety and Efficacy of Combigan® Ophthalmic Solution in Korea
The document reports the completion of a Korea-based trial evaluating the safety and efficacy of Combigan ophthalmic solution for open-angle…
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CLINICAL_TRIALS trial_result · 2014-03-28Clinical Trial Update: Observational Study of Lumigan® 0.01% Treatment for Patients With Primary Open Angle Glaucoma or Ocular Hypertension
This document reports the results of an observational study evaluating Lumigan 0.01% (bimatoprost) in patients with primary open-angle glauc…
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CLINICAL_TRIALS trial_result · 2014-03-17Clinical Trial Update: A Study Assessing PG286 Ophthalmic Solution, 0.5% Compared to Its Individual Components for 28 Days [Phase 2]
Phase 2 trial evaluating PG286 ophthalmic solution 0.5% versus its components over 28 days in open-angle glaucoma and ocular hypertension ha…
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CLINICAL_TRIALS trial_result · 2014-03-13Clinical Trial Update: Fixed Combination Brinzolamide 1%/Timolol 0.5% Versus Brinzolamide 1% + Timolol 0.5% in Open-Angle Glaucoma or Ocular Hypertension [Phase 3]
A Phase 3 trial compared a fixed-dose combination of brinzolamide 1% and timolol 0.5% with separate brinzolamide 1% plus timolol 0.5% in ope…
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CLINICAL_TRIALS trial_result · 2014-03-11Clinical Trial Update: Safety/Efficacy Study: OPA-6566 Ophthalmic Solution in Subjects With Primary Open-Angle Glaucoma or Ocular Hypertension [Phase 1, Phase 2]
This document reports the completion of a Phase 1/Phase 2 safety and efficacy study of OPA-6566 Ophthalmic Solution in subjects with primary…
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CLINICAL_TRIALS trial_result · 2014-03-06Clinical Trial Update: Safety and Efficacy of the GTS400 Stent in Conjunction With Cataract [Phase 3]
Phase 3 clinical trial assessing the safety and efficacy of the GTS400 stent in conjunction with cataract surgery for open-angle glaucoma ha…
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CLINICAL_TRIALS trial_result · 2014-03-06Clinical Trial Update: Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID and Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension [Phase 3]
Phase 3 study comparing brinzolamide/brimonidine fixed-dose combination given twice daily to its individual components in open-angle glaucom…
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CLINICAL_TRIALS trial_result · 2014-03-05Clinical Trial Update: Study of Vitamin A and Carbomer in Comforting the Ocular Surface Irritations of Glaucoma Patients [NA]
A completed clinical trial evaluated the use of Vitamin A and Carbomer to comfort ocular surface irritations in patients with primary open-a…
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CLINICAL_TRIALS trial_result · 2014-02-03Clinical Trial Update: Study on Ocular Blood Flow and the Orbital Cerebrospinal Fluid Pressure in Glaucoma
This trial update reports a completed study evaluating ocular blood flow and orbital cerebrospinal fluid pressure in patients with open-angl…
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CLINICAL_TRIALS trial_result · 2014-01-28Clinical Trial Update: A Safety and Efficacy Study of Bimatoprost 0.01% in Primary Open-Angle Glaucoma (POAG) or Ocular Hypertension (OH) [Phase 4]
A Phase 4 safety and efficacy study evaluating bimatoprost 0.01% in primary open-angle glaucoma or ocular hypertension; results were posted …
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FDA approval · 2014-01-22FDA Approved: ALPHAGAN P — Supplemental Application (Allergan, Inc.)
FDA approved a supplemental NDA for ALPHAGAN P (brimonidine tartrate) from Allergan, Inc.
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CLINICAL_TRIALS trial_result · 2014-01-20Clinical Trial Update: Efficacy of 24-hour Intraocular Pressure Fluctuation Recording With the SENSIMED Triggerfish Contact Lens Sensor [NA]
This clinical trial update reports results on the efficacy of 24-hour intraocular pressure fluctuation recording using the SENSIMED Triggerf…
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CLINICAL_TRIALS trial_result · 2014-01-10Clinical Trial Update: A Study of the L-PPDS With Adjunctive Xalatan® Eye Drops in Subjects With OH or OAG [Phase 2]
This update reports the completion of a Phase 2 study evaluating L-PPDS with adjunctive Xalatan eye drops in individuals with ocular hyperte…
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CLINICAL_TRIALS trial_result · 2014-01-10Clinical Trial Update: Efficacy of Changing to DUOTRAV® From Prior Therapy [Phase 4]
Phase 4 trial assessing switching to DuoTrav from prior therapy in open-angle glaucoma, ocular hypertension, and pigment dispersion glaucoma…
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CLINICAL_TRIALS trial_result · 2014-01-08Clinical Trial Update: Comparative Effectiveness of Treatment Strategies for Primary Open-Angle Glaucoma
Completed clinical trial evaluating comparative effectiveness of treatment strategies for primary open-angle glaucoma.
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CLINICAL_TRIALS trial_result · 2013-12-13Clinical Trial Update: Patient Preference Comparison of AZARGA Versus COSOPT [Phase 4]
Phase 4 trial comparing patient preference between AZARGA and COSOPT in open-angle glaucoma and ocular hypertension; results were completed …
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CLINICAL_TRIALS research · 2013-12-12Clinical Trial Update: Early Diagnosis, Pathogenesis and Progression of Open Angle Glaucoma
This item provides a clinical trial update on early diagnosis, pathogenesis, and progression of open-angle glaucoma. The study includes Prim…
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CLINICAL_TRIALS withdrawal · 2013-11-26Clinical Trial Update: Prevalence of Dyschromatopsia in Glaucoma Patients
A trial investigating the prevalence of dyschromatopsia in open-angle glaucoma has been withdrawn. The study status indicates it was cancele…
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: Corneal Biomechanics and Continuous IOP Monitoring Using Soft Contact Lenses in Glaucomatous Patients [NA]
A completed clinical trial evaluating corneal biomechanics and continuous intraocular pressure monitoring using soft contact lenses in patie…
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CLINICAL_TRIALS trial_result · 2013-11-07Clinical Trial Update: Blood-aqueous Barrier Changes After the Use of Timolol and Prostaglandin Analogues Fixed Combination in Pseudophakic Patients With POAG [Phase 4]
A Phase 4 trial evaluated blood-aqueous barrier changes after a fixed combination of timolol and a prostaglandin analogue in pseudophakic pa…
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CLINICAL_TRIALS trial_result · 2013-11-06Clinical Trial Update: Safety and Efficacy of AGN-210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Open-Angle Glaucoma or Ocular Hypertension [Phase 2]
Phase 2 study comparing AGN-210669 ophthalmic solution with bimatoprost ophthalmic solution in open-angle glaucoma or ocular hypertension; r…
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CLINICAL_TRIALS trial_result · 2013-10-25Clinical Trial Update: Safety and Intraocular Pressure (IOP) Lowering Effect of AL-59412C [Phase 2]
A Phase 2 trial evaluating AL-59412C in open-angle glaucoma and ocular hypertension reported safety data and intraocular pressure-lowering e…
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CLINICAL_TRIALS trial_result · 2013-10-18Clinical Trial Update: Travoprost 3-Month Safety and Efficacy Study [Phase 3]
Phase 3 trial evaluating Travoprost for safety and efficacy in open-angle glaucoma and ocular hypertension has completed, with results poste…
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CLINICAL_TRIALS trial_result · 2013-10-18Clinical Trial Update: Safety and Efficacy of AGN 210669 Ophthalmic Solution in Patients With Ocular Hypertension or Primary Open-Angle Glaucoma [Phase 1, Phase 2]
This clinical trial update reports on the safety and efficacy of AGN 210669 Ophthalmic Solution in patients with ocular hypertension or prim…