Open-angle Glaucoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-04-21Clinical Trial Update: A 12 Week Comparison of DuoTrav and Xalacom in Open-Angle Glaucoma [Phase 4]
A Phase 4 trial comparing two fixed-dose combination eye drops, DuoTrav (travoprost/timolol) and Xalacom (latanoprost/timolol), in open-angl…
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CLINICAL_TRIALS trial_result · 2015-04-20Clinical Trial Update: Multicentric Observational Study on Quality of Life in Glaucoma
A multicenter observational study assessing quality of life in patients with primary open-angle glaucoma has completed.
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CLINICAL_TRIALS trial_result · 2015-04-13Clinical Trial Update: Evaluation of Intraocular Pressure Using Simbrinza™ in Patients With Open-Angle Glaucoma or Ocular Hypertension [Phase 4]
A Phase 4 trial evaluating intraocular pressure with Simbrinza in patients with open-angle glaucoma or ocular hypertension has completed, wi…
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CLINICAL_TRIALS research · 2015-04-08Clinical Trial Update: aICP in Glaucoma and Papilledema [NA]
This entry notes a clinical trial involving aICP for open-angle glaucoma and papilledema; the current trial status is unknown.
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CLINICAL_TRIALS withdrawal · 2015-03-10Clinical Trial Update: Choroidal Blood Flow Response to Hand-grip Test in Progressive Glaucoma
A clinical trial on choroidal blood flow response to hand-grip exercise in progressive glaucoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-03-03Clinical Trial Update: Ginkgo Biloba and Ocular Blood Flow in Primary Open-angle Glaucoma [Phase 2]
Phase 2 clinical trial update assessing Ginkgo Biloba for improving ocular blood flow in primary open-angle glaucoma; the study has complete…
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CLINICAL_TRIALS research · 2015-02-05Clinical Trial Update: Posterior Cornea in Primary Open Angle Glaucoma
A clinical trial update evaluating the role of the posterior cornea in primary open-angle glaucoma; no results are reported in this update.
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CLINICAL_TRIALS trial_result · 2015-01-21Clinical Trial Update: Multiple Dose-parallel-group Study of AMA0076 in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension [Phase 2]
A Phase 2 multiple-dose, parallel-group study evaluating AMA0076 in patients with primary open-angle glaucoma or ocular hypertension has com…
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CLINICAL_TRIALS trial_result · 2015-01-21Clinical Trial Update: Study of INS115644 Ophthalmic Solution in Subjects With Ocular Hypertension or Glaucoma [Phase 1]
Phase 1 trial update on INS115644 ophthalmic solution in subjects with ocular hypertension or open-angle glaucoma; the study status is COMPL…
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CLINICAL_TRIALS trial_result · 2015-01-06Clinical Trial Update: Pharmacokinetics, Efficacy and Safety Assessment of T2345 Compared With Active Comparator in Newly Diagnosed Patients With Open-angle Glaucoma or Ocular Hypertension [Phase 2]
A Phase 2 trial comparing T2345 to an active comparator in newly diagnosed open-angle glaucoma or ocular hypertension, with pharmacokinetics…
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CLINICAL_TRIALS trial_result · 2014-12-30Clinical Trial Update: Structure Function Correlation in Primary Open Angle Glaucoma
This update reports on the completion of a clinical trial exploring the relationship between structural measures and functional outcomes in …
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FDA approval · 2014-12-19FDA Approved: BETAXOLOL — Supplemental Application (Epic Pharma LLC)
The FDA approved a supplemental application (ANDA075541) for Betaxolol from Epic Pharma LLC, marking an approved change under the ANDA proce…
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CLINICAL_TRIALS research · 2014-12-17Clinical Trial Update: A Study of the VISION5 Product in Patients With Glaucoma or Ocular Hypertension [Phase 1]
Phase 1 clinical trial update for the VISION5 product in ocular hypertension and primary open-angle glaucoma. The study status is completed.
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CLINICAL_TRIALS withdrawal · 2014-12-11Clinical Trial Update: Latanoprost/Brinzolamide BID Versus Latanoprost BID in Patients With OAG or OH [Phase 3]
A Phase 3 trial comparing latanoprost/brinzolamide to latanoprost alone in open-angle glaucoma or ocular hypertension has been withdrawn.
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CLINICAL_TRIALS research · 2014-12-09Clinical Trial Update: High Frequency Deep Sclerotomy (HFDS) ab Interno a Combination Surgical Intervention Using Cataract Surgery to Lower IOP [NA]
Clinical trial update describing High Frequency Deep Sclerotomy (HFDS) performed ab interno in combination with cataract surgery to lower in…
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CLINICAL_TRIALS trial_result · 2014-12-08Clinical Trial Update: Safety Study of Latanoprost Slow Release Insert [Phase 1]
Phase 1 safety study of the latanoprost slow-release insert was terminated in participants with primary open-angle glaucoma or ocular hypert…
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CLINICAL_TRIALS trial_result · 2014-11-24Clinical Trial Update: IOP Fluctuations in Patients With Sleep Apnea With or Without Primary Open Angle Glaucoma Using Positive Airway Pressure [NA]
A completed trial assessed intraocular pressure fluctuations in patients with obstructive sleep apnea, with or without primary open-angle gl…
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CLINICAL_TRIALS withdrawal · 2014-11-21Clinical Trial Update: Progressive Open Angle Glaucoma (OAG) and Ocular Blood Flow [NA]
A clinical trial investigating progressive open-angle glaucoma and ocular blood flow has been withdrawn.
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CLINICAL_TRIALS trial_result · 2014-11-17Clinical Trial Update: PIO Laser Sclerectomy IOP SLT Sclerectomy [NA]
A completed clinical trial evaluating PIO Laser Sclerectomy for intraocular pressure management in primary open-angle glaucoma.
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CLINICAL_TRIALS trial_result · 2014-11-14Clinical Trial Update: Effect of Xalacom® (Latanoprost/Timolol) and Combigan® (Brimonidine/Timolol) Fixed Combination on Intraocular Pressure and Ocular Blood Flow in Patients With Primary Open Angle Glaucoma or Ocular Hypertension [NA]
A completed clinical trial update evaluating the effects of fixed-combination glaucoma therapies Xalacom (latanoprost/timolol) and Combigan …
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CLINICAL_TRIALS trial_result · 2014-10-28Clinical Trial Update: The Effects of Preservative-free Prostaglandin Eye Drops in Sign and Symptoms on the Eyes of Patients With Glaucoma [Phase 4]
Phase 4 clinical trial update evaluating the effects of preservative-free prostaglandin eye drops on signs and symptoms in patients with gla…
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CLINICAL_TRIALS trial_result · 2014-09-30Clinical Trial Update: Study to Compare the Safety and Efficacy of ALZ-1101 to Latanoprost in Patients With Intraocular Pressure Inadequately Controlled by Latanoprost [Phase 2]
A Phase 2 study comparing ALZ-1101 to Latanoprost in patients whose intraocular pressure remains inadequately controlled by Latanoprost has …
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FDA approval · 2014-09-29FDA Approved: LUMIGAN — Supplemental Application (Allergan, Inc.)
The FDA approved a supplemental application for Lumigan (bimatoprost) submitted by Allergan, Inc.
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FDA approval · 2014-09-25FDA Approved: BETAXOLOL HYDROCHLORIDE — Supplemental Application (Sandoz Inc)
FDA approved a supplemental application for betaxolol hydrochloride (Sandoz Inc). The action involves updating the product labeling.
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FDA approval · 2014-09-25FDA Approved: TIMOLOL GFS — Supplemental Application (Sandoz Inc)
FDA approved the supplemental application for TIMOLOL GFS (timolol maleate) from Sandoz Inc.