Open-angle Glaucoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-03-14Clinical Trial Update: The Diurnal and Nocturnal Effect of Simbrinza and Timolol on Intraocular Pressure and Ocular Perfusion Pressure
A completed trial update evaluating the diurnal and nocturnal effects of Simbrinza and Timolol on intraocular pressure and ocular perfusion …
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CLINICAL_TRIALS trial_result · 2016-03-09Clinical Trial Update: Determinants of Compliance With Glaucoma Therapy
A completed clinical trial investigating determinants of patient compliance with glaucoma therapy in open-angle glaucoma.
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CLINICAL_TRIALS trial_result · 2016-02-29Clinical Trial Update: Impact Post-operative Treatment on Intraocular Pressure Post-SLT on Patients With Primary Open-angle Glaucoma [NA]
The update discusses results of a completed clinical trial examining how postoperative treatment affects intraocular pressure after selectiv…
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: A 28 Day Study of ONO-9054 Ophthalmic Solution in Subjects With Ocular Hypertension (OHT) or Open-angle Glaucoma (OAG) [Phase 2]
Phase 2, 28-day study of ONO-9054 ophthalmic solution in ocular hypertension and open-angle glaucoma has completed.
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: Trabectome Versus Trabeculectomy With Mitomycin C in Patients With Open Angle Glaucoma [Phase 3]
Phase 3 trial comparing Trabectome to trabeculectomy with mitomycin C in open-angle glaucoma has been terminated.
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CLINICAL_TRIALS research · 2016-02-17Clinical Trial Update: Following Patients After Selective and Pascal Laser Trabeculoplasty for Treatment of Chronic Open-Angle Glaucoma
A clinical trial update reports on patients treated with selective and Pascal laser trabeculoplasty for chronic open-angle glaucoma; the stu…
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CLINICAL_TRIALS trial_result · 2016-02-08Clinical Trial Update: AqueSys Microfistula Implant in Refractory Glaucoma [Phase 3]
Phase 3 trial of the AqueSys Microfistula Implant for refractory open-angle glaucoma has completed.
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CLINICAL_TRIALS research · 2016-02-02Clinical Trial Update: Study to Compare Standard Perimetry With the New Scotoma-Oriented Perimetry (SCOPE) Using a New Fast German Adaptive Threshold Estimation (GATE) in Glaucoma Patients
A clinical trial comparing standard perimetry with scotoma-oriented perimetry (SCOPE) using a new fast German adaptive threshold estimation …
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FDA label_change · 2016-01-20FDA Approved: SIMBRINZA — Supplemental Application (Alcon Laboratories, Inc.)
FDA approved a supplemental application for SIMBRINZA (brinzolamide/brimonidine tartrate) submitted by Alcon Laboratories, Inc., resulting i…
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FDA label_change · 2016-01-15FDA Approved: SIMBRINZA — Supplemental Application (Alcon Laboratories, Inc.)
The FDA approved a supplemental application for SIMBRINZA (brinzolamide/brimonidine tartrate) to update the product labeling.
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CLINICAL_TRIALS trial_result · 2015-12-29Clinical Trial Update: 6-Week Proof-of-Concept Study of Travoprost/Brinzolamide Ophthalmic Suspension in Subjects With Open-Angle Glaucoma or Ocular Hypertension [Phase 2]
A Phase 2 proof-of-concept study evaluated a fixed-dose Travoprost/brinzolamide ophthalmic suspension in open-angle glaucoma or ocular hyper…
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FDA approval · 2015-12-09FDA Approved: LATANOPROST — Supplemental Application (Bausch & Lomb Incorporated)
The FDA approved a supplemental application for latanoprost filed by Bausch & Lomb Incorporated.
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CLINICAL_TRIALS withdrawal · 2015-12-08Clinical Trial Update: iDropper Usability in Glaucoma [Phase 1]
A Phase 1 usability trial of the iDropper device for open-angle glaucoma has been withdrawn.
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FDA approval · 2015-11-27FDA Approved: DORZOLAMIDE HYDROCHLORIDE — Supplemental Application (Advagen Pharma Ltd.)
The FDA approved Advagen Pharma Ltd.'s supplemental application for dorzolamide hydrochloride, authorizing a generic version of the drug.
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CLINICAL_TRIALS trial_result · 2015-11-17Clinical Trial Update: TF (SENSIMED Triggerfish) in Intraocular Anti-VEGF (Vascular Endothelial Growth Factor) Injection [Phase 4]
Phase 4 trial update indicates termination of the SENSIMED Triggerfish study involving intraocular anti-VEGF injections for neovascular age-…
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CLINICAL_TRIALS trial_result · 2015-11-17Clinical Trial Update: Relationship Between 24-hour IOP Pattern and the 24-hour Blood Pressure Pattern in Patients With POAG [NA]
A completed clinical trial evaluating the relationship between 24-hour intraocular pressure patterns and 24-hour blood pressure patterns in …
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CLINICAL_TRIALS trial_result · 2015-11-17Clinical Trial Update: IOP Fluctuations in Patients With Primary Open-angle Glaucoma, Before and After Selective Laser Trabeculoplasty [NA]
The document reports a completed clinical trial assessing intraocular pressure fluctuations in patients with primary open-angle glaucoma bef…
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FDA approval · 2015-11-10FDA Approved: BRIMONIDINE TARTRATE — Supplemental Application (Sandoz Inc)
The FDA approved a supplemental application for brimonidine tartrate submitted by Sandoz Inc.
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CLINICAL_TRIALS trial_result · 2015-11-09Clinical Trial Update: Safety and Efficacy of Triple Combination Therapy in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension [Phase 3]
Phase 3 clinical trial assessing the safety and efficacy of a triple combination therapy in patients with primary open-angle glaucoma or ocu…
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FDA approval · 2015-11-05FDA Approved: SIMBRINZA — Supplemental Application (Alcon Laboratories, Inc.)
FDA approved a supplemental application for SIMBRINZA (brinzolamide/brimonidine tartrate) submitted by Alcon Laboratories, Inc.
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CLINICAL_TRIALS trial_result · 2015-10-26Clinical Trial Update: A Study of Bimatoprost 0.01% in the Clinical Setting
The document reports the completion of a clinical trial evaluating bimatoprost 0.01% for primary open-angle glaucoma and ocular hypertension…
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CLINICAL_TRIALS trial_result · 2015-10-21Clinical Trial Update: Imaging Lens Deposits in Exfoliation Syndrome
A Duke University-sponsored clinical trial investigating imaging lens deposits in exfoliation syndrome has been terminated.
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FDA label_change · 2015-10-20FDA Approved: TIMOPTIC-XE — Supplemental Application (Bausch & Lomb Incorporated)
FDA granted a supplemental approval for TIMOPTIC-XE (timolol maleate) from Bausch & Lomb, updating the product labeling per the supplemental…
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CLINICAL_TRIALS research · 2015-10-08Clinical Trial Update: Functional Brain Changes of Primary Open-angle Glaucoma Patients
An update on a clinical trial studying functional brain changes in patients with primary open-angle glaucoma; the trial status is listed as …
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CLINICAL_TRIALS research · 2015-10-01Clinical Trial Update: RESEARCH PROTOCOL: Glaucoma Treatment Adherence and Persistence [NA]
This document outlines the protocol for a research study evaluating adherence and persistence in glaucoma treatment.