Open-angle Glaucoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-06-07Clinical Trial Update: PAIR Study-PAP And IOP Relationship: Study 1 [NA]
This clinical trial update reports that the PAIR Study 1, investigating the relationship between PAP therapy and intraocular pressure in peo…
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: Long-Term Safety of Latanoprostene Bunod Ophthalmic Solution 0.024% in Japanese Subjects With OAG or OHT [Phase 3]
Phase 3 long-term safety update for latanoprostene bunod ophthalmic solution 0.024% in Japanese subjects with open-angle glaucoma or ocular …
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CLINICAL_TRIALS research · 2018-06-06Clinical Trial Update: PAIR Study-PAP And IOP Relationship: Study 2
This clinical trial update notes the completion of PAIR Study 2, which investigates the relationship between PAP therapy and intraocular pre…
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CLINICAL_TRIALS trial_result · 2018-04-20Clinical Trial Update: Bimatoprost Ocular Insert Compared to Topical Timolol Solution in Patients With Glaucoma or Ocular Hypertension [Phase 2]
A Phase 2 trial comparing a bimatoprost ocular insert to topical timolol solution in patients with primary open-angle glaucoma or ocular hyp…
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CLINICAL_TRIALS trial_result · 2018-04-18Clinical Trial Update: Multi-center Phase II Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension [Phase 2]
A multi-center Phase II trial evaluating the safety and efficacy of DE-117 ophthalmic solution in adults with primary open-angle glaucoma or…
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CLINICAL_TRIALS trial_result · 2018-04-18Clinical Trial Update: Multi-center Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension [Phase 2]
Phase 2 trial evaluating safety and efficacy of DE-117 ophthalmic solution in open-angle glaucoma or ocular hypertension completed.
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Nocturnal/Diurnal Intraocular Pressure-Lowering Effect of Netarsudil Ophthalmic Solution [Phase 2]
Phase 2 trial update showing nocturnal and diurnal intraocular pressure-lowering effects of netarsudil ophthalmic solution, with results pos…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Study Comparing the Safety and Efficacy of AR-13324 to Latanoprost in Patients With Elevated Intraocular Pressure [Phase 2]
Phase 2 study comparing AR-13324 to Latanoprost in patients with elevated intraocular pressure has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2018-04-13Clinical Trial Update: Double-masked Study of AR-13324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension [Phase 3]
A Phase 3, double-masked trial of AR-13324 ophthalmic solution in ocular hypertension and open-angle glaucoma has completed, with results po…
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CLINICAL_TRIALS trial_result · 2018-04-06Clinical Trial Update: Evaluation of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma and Ocular Hypertension [Phase 3]
Phase 3 study evaluating netarsudil ophthalmic solution in ocular hypertension and open-angle glaucoma completed with results posted in 2018…
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CLINICAL_TRIALS trial_result · 2018-04-06Clinical Trial Update: Double-masked Study of Netarsudil (AR-13324) Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension [Phase 3]
This clinical trial update reports results from a double-masked Phase 3 study of Netarsudil ophthalmic solution in adults with open-angle gl…
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CLINICAL_TRIALS trial_result · 2018-04-04Clinical Trial Update: Micropulse Laser Trabeculoplasty as Adjunctive Treatment in Patients With Pseudoexfoliation Glaucoma [NA]
A completed clinical trial evaluating micropulse laser trabeculoplasty as an adjunctive treatment for pseudoexfoliation glaucoma and primary…
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CLINICAL_TRIALS trial_result · 2018-04-02Clinical Trial Update: Comparison of Gonioscopy With Cirrus and Visante
This clinical trial update reports a comparison of gonioscopy with Cirrus and Visante imaging for assessing anterior chamber angle status in…
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CLINICAL_TRIALS trial_result · 2018-03-14Clinical Trial Update: A Phase 1/2 Multicenter, Randomized, Study to Evaluate the Safety and Efficacy of VS101 Subconjunctival Latanoprost Insert in Subjects With Open-Angle Glaucoma or Ocular Hypertension [Phase 1, Phase 2]
This completed Phase 1/2 multicenter randomized trial evaluated the safety and preliminary efficacy of VS101, a subconjunctival latanoprost …
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CLINICAL_TRIALS trial_result · 2018-03-14Clinical Trial Update: A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO5093151 in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT). [Phase 1]
A Phase 1 clinical trial evaluating the safety, tolerability, pharmacokinetics, and pharmacodynamics of RO5093151 in patients with primary o…
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CLINICAL_TRIALS trial_result · 2018-03-09Clinical Trial Update: A Study of the iStent in Combo With Cataract Surgery in Newly Diagnosed Open Angle Glaucoma or OH Patients. [NA]
This is a completed clinical trial assessing the iStent device in combination with cataract surgery for open-angle glaucoma. The provided sn…
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CLINICAL_TRIALS trial_result · 2018-02-28Clinical Trial Update: Phase I Dose Escalation Study to Investigate the Safety of ISTH0036 in Subjects With Glaucoma Undergoing Trabeculectomy [Phase 1]
A completed Phase I dose-escalation trial evaluating the safety of ISTH0036 in subjects with primary open-angle glaucoma undergoing trabecul…
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CLINICAL_TRIALS trial_result · 2018-02-22Clinical Trial Update: Study of AR-13324 in Patients With Elevated Intraocular Pressure [Phase 2]
Phase 2 trial results for AR-13324 in patients with elevated intraocular pressure have been posted.
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CLINICAL_TRIALS trial_result · 2018-02-15Clinical Trial Update: Study of Fixed-Dose Combinations of Trabodenoson and Latanoprost in Adults With OHT or POAG [Phase 2]
Phase 2 trial update for fixed-dose combinations of trabodenoson and latanoprost in adults with ocular hypertension or primary open-angle gl…
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CLINICAL_TRIALS trial_result · 2018-02-09Clinical Trial Update: The Effect of Sponge Versus No-Sponge Placement of Mitomycin-C on the Outcomes of Trabeculectomy With Ex-PRESS Glaucoma Filtration Device [Phase 2]
Phase 2 trial evaluating sponge versus no-sponge placement of mitomycin-C in Trabeculectomy with Ex-PRESS device for primary open-angle glau…
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CLINICAL_TRIALS trial_result · 2018-01-10Clinical Trial Update: Laser-1st vs Drops-1st for Glaucoma and Ocular Hypertension [Phase 4]
A Phase 4 trial comparing Laser-1st vs Drops-1st strategies for primary open-angle glaucoma and ocular hypertension has completed.
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FDA approval · 2017-12-18FDA Approved: RHOPRESSA — Original Application (Alcon Laboratories, Inc.)
FDA approved Rhopressa (netarsudil) from Alcon as an original NDA, indicated to reduce elevated intraocular pressure in adults with open-ang…
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CLINICAL_TRIALS trial_result · 2017-12-18Clinical Trial Update: Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Surgical Therapy, Treated With Two Trabecular Micro-bypass Stents (iStent)or Travoprost [Phase 4]
Phase 4 trial update evaluating two trabecular micro-bypass stents (iStent) versus travoprost in open-angle glaucoma and related conditions.
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CLINICAL_TRIALS trial_result · 2017-12-18Clinical Trial Update: Prospective Evaluation of Open-Angle Glaucoma Subjects on One Topical Hypotensive Medication Treated With Two iStents [Phase 4]
Phase 4 clinical trial evaluating open-angle glaucoma patients treated with two iStents in addition to a topical hypotensive medication.
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CLINICAL_TRIALS trial_result · 2017-12-02Clinical Trial Update: A Phase II Study to Evaluate the Additivity of Trabodenoson to Latanoprost in Adults With Ocular Hypertension or Primary Open-Angle Glaucoma [Phase 2]
A Phase II study evaluated whether trabodenoson adds to latanoprost in adults with ocular hypertension or primary open-angle glaucoma, and t…