Open-angle Glaucoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-09-04Clinical Trial Update: Assessment of Intraocular Pressure (IOP) Control in Subjects With Open-Angle Glaucoma or Ocular Hypertension Treated With Travoprost 0.004% (TRAVATAN® Z) or Bimatoprost 0.01% (LUMIGAN®) [Phase 4]
Phase 4 study comparing intraocular pressure control in open-angle glaucoma or ocular hypertension patients treated with travoprost 0.004% v…
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CLINICAL_TRIALS trial_result · 2013-08-15Clinical Trial Update: Impact of a Tolerability Switch to Dorzolamide/Timolol Preservative-free Fixed Combination on Ocular Surface Symptoms
A completed clinical trial evaluating tolerability when switching to a preservative-free dorzolamide/timolol fixed combination for open-angl…
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CLINICAL_TRIALS trial_result · 2013-07-08Clinical Trial Update: A Comfort Study of Brinzolamide 1% / Brimonidine 0.2% Fixed Combination, Brinzolamide 1% and Brimonidine 0.2% [Phase 2]
A Phase 2 study of brinzolamide 1% / brimonidine 0.2% fixed combination and its individual components in open-angle glaucoma and ocular hype…
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CLINICAL_TRIALS trial_result · 2013-07-04Clinical Trial Update: Three Month Efficacy/Safety Study With a 3-Month Safety Extension of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% or Brimonidine 0.2% [Phase 3]
Phase 3 study comparing the fixed-dose combination brinzolamide 1%/brimonidine 0.2% to each component alone in open-angle glaucoma and ocula…
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CLINICAL_TRIALS trial_result · 2013-07-04Clinical Trial Update: Safety and Efficacy of Brinzolamide/Brimonidine Fixed Combination [Phase 2]
A Phase 2 trial evaluating the safety and efficacy of a Brinzolamide/Brimonidine fixed combination for open-angle glaucoma and ocular hypert…
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CLINICAL_TRIALS trial_result · 2013-06-27Clinical Trial Update: Transconjunctival Needling Revision Versus Medical Treatment [Phase 2]
A Phase 2 clinical trial comparing transconjunctival needling revision surgery to medical therapy for primary open-angle glaucoma has comple…
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CLINICAL_TRIALS trial_result · 2013-06-20Clinical Trial Update: A Study of the Rate of Progression of Glaucoma During a Follow-up Period of Two Years
A completed clinical trial update on the rate of progression of open-angle glaucoma over a two-year follow-up period.
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CLINICAL_TRIALS trial_result · 2013-06-10Clinical Trial Update: Dose Finding Clinical Trial With SYL040012 to Evaluate the Tolerability and Effect on Intraocular Pressure in Subjects With Ocular Hypertension or Open Angle Glaucoma [Phase 2]
This Phase 2 dose-finding study evaluates the tolerability and effect on intraocular pressure of SYL040012 in people with ocular hypertensio…
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CLINICAL_TRIALS trial_result · 2013-06-03Clinical Trial Update: Single and Multiple Dose Escalation and Two-sequence Crossover Study of ONO-9054 in Patients With Ocular Hypertension or Mild Open-angle Glaucoma [Phase 1]
This Phase 1 study evaluated single and multiple dose escalation and a two-sequence crossover design for ONO-9054 in ocular hypertension or …
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CLINICAL_TRIALS trial_result · 2013-05-31Clinical Trial Update: Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost to Preservative Free Tafluprost Eye Drops [Phase 3]
Phase 3 trial update examining ocular signs and symptoms when glaucoma patients switched from latanoprost to preservative-free tafluprost ey…
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CLINICAL_TRIALS trial_result · 2013-05-15Clinical Trial Update: Study of TRAVATAN in Subjects With Iris Pigmentation Changes
This clinical trial update reports termination of a study evaluating TRAVATAN (travoprost) in subjects with open-angle glaucoma or ocular hy…
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CLINICAL_TRIALS trial_result · 2013-05-14Clinical Trial Update: A Multicenter Study of the Pigmentation in the Trabecular Meshwork After Two Years of Treatment With TRAVATAN 0.004% Ophthalmic Solution
This clinical trial evaluated long-term pigmentation in the trabecular meshwork after two years of Travatan 0.004% ophthalmic solution for o…
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CLINICAL_TRIALS trial_result · 2013-05-13Clinical Trial Update: Efficacy and Safety Study of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% and Brimonidine 0.2% [Phase 3]
Phase 3 trial comparing fixed-dose brinzolamide 1%/brimonidine 0.2% versus the individual components brinzolamide 1% and brimonidine 0.2% fo…
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CLINICAL_TRIALS trial_result · 2013-05-07Clinical Trial Update: Latanoprost Versus Tafluprost: 24-hour Intraocular Pressure (IOP) [Phase 4]
Phase 4 clinical trial comparing 24-hour intraocular pressure control between latanoprost and tafluprost in primary open-angle glaucoma or o…
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CLINICAL_TRIALS trial_result · 2013-04-24Clinical Trial Update: Safety and Effects of Brimonidine Intravitreal Implant in Patients With Glaucomatous Optic Neuropathy [Phase 2]
This report covers safety and effects from a Phase 2 trial of brimonidine implanted intravitreally in patients with glaucomatous optic neuro…
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CLINICAL_TRIALS trial_result · 2013-03-29Clinical Trial Update: A Study of the Glaukos Trabecular Micro-bypass Stent in Open Angle Glaucoma Subjects 1 Stent Versus 2 [Phase 4]
Phase 4 clinical trial comparing single-stent versus two-stent implantation with the Glaukos Trabecular Micro-bypass Stent in open-angle gla…
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CLINICAL_TRIALS trial_result · 2013-03-28Clinical Trial Update: Travoprost 0.004%/Timolol 0.5% Versus Latanoprost 0.005%/Timolol in Chinese Patients With Open-Angle Glaucoma or Ocular Hypertension [Phase 3]
Phase 3 trial comparing travoprost 0.004%/timolol 0.5% versus latanoprost 0.005%/timolol 0.5% in Chinese patients with open-angle glaucoma o…
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CLINICAL_TRIALS trial_result · 2013-03-13Clinical Trial Update: Tafluprost-Timolol Preservative-free Fixed Dose Combination (FDC) Superiority Study Against Monotherapies [Phase 3]
Phase 3 superiority study evaluating a preservative-free fixed-dose combination of tafluprost and timolol versus each monotherapy in ocular …
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CLINICAL_TRIALS trial_result · 2013-02-26Clinical Trial Update: Safety and Efficacy of Bimatoprost/Timolol Fixed Combination Versus Latanoprost in Patients With Open-Angle Glaucoma Who Have Never Been Treated [Phase 4]
Phase 4 trial comparing fixed combination bimatoprost/timolol to latanoprost in treatment-naïve open-angle glaucoma patients; results posted…
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CLINICAL_TRIALS trial_result · 2013-02-25Clinical Trial Update: A Investigator Masked Parallel Comparison of Tolerability of Combigan and Cosopt
This clinical trial update reports an investigator-m masked, parallel comparison of tolerability between Combigan and Cosopt in patients wit…
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CLINICAL_TRIALS trial_result · 2013-02-06Clinical Trial Update: Validation of Retinal Oximetry in Glaucoma Patients: a Structural and Functional Correlation
The completed study validates retinal oximetry as a structural and functional correlate in open-angle glaucoma and normal tension glaucoma.
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CLINICAL_TRIALS trial_result · 2013-02-06Clinical Trial Update: Waveform Analysis of the Doppler Curve of Ophthalmic Arteries in Glaucoma Patients
This clinical trial update reports on waveform analysis of the Doppler curve in ophthalmic arteries among glaucoma patients, focusing on ope…
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CLINICAL_TRIALS trial_result · 2012-12-25Clinical Trial Update: Study Evaluating the Safety and Intraocular Pressure (IOP) Lowering Response of Brimonidine Tartrate Ophthalmic Solution in Subjects With Open Angle Glaucoma or Ocular Hypertension [Phase 1]
A Phase 1 trial assessing safety and intraocular pressure lowering response of brimonidine tartrate ophthalmic solution in open-angle glauco…
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CLINICAL_TRIALS trial_result · 2012-12-17Clinical Trial Update: ELAZOP Switching Study in Korea [Phase 4]
Phase 4 clinical trial update for the ELAZOP switching study in Korea indicates the study has completed.
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CLINICAL_TRIALS trial_result · 2012-12-17Clinical Trial Update: Safety and Efficacy Trial to Treat Open-Angle Glaucoma or Ocular Hypertension [Phase 1, Phase 2]
A clinical trial update from Santen Inc. describes a safety and efficacy study in Phase 1/2 for open-angle glaucoma and ocular hypertension …