Open-angle Glaucoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-07-12Clinical Trial Update: Efficacy of NSAID vs. Steroid-NSAID Combo Post-Selective Laser Trabeculoplasty: Phase 4, Single-Center RCT [Phase 4]
Phase 4 trial comparing NSAID alone versus a steroid-NSAID combination to manage postoperative inflammation after selective laser trabeculop…
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CLINICAL_TRIALS research · 2024-06-24Clinical Trial Update: CRISPR/Cas9 Instantaneous Gene Editing Therapy to Intraocular Hypertensive POAG With MYOC Mutation [NA]
A CRISPR/Cas9 instantaneous gene editing therapy for MYOC-mutant primary open-angle glaucoma is in a clinical trial and currently recruiting…
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CLINICAL_TRIALS research · 2024-06-12Clinical Trial Update: The A D A G I O Study
Update on the ADAGIO Study indicating the trial is not yet recruiting for open-angle glaucoma and ocular hypertension.
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: Travoprost Intraocular Implant in Conjunction With Cataract Surgery [Phase 3]
A Phase 3 trial update for a travoprost intraocular implant used during cataract surgery for open-angle glaucoma and ocular hypertension; th…
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: Nicotinamide in Glaucoma (NAMinG): A Randomised, Placebo-controlled, Multi-centre, Phase III Trial [Phase 3]
NAMinG is a phase III, randomized, placebo-controlled trial evaluating nicotinamide for open-angle glaucoma, with recruitment ongoing across…
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CLINICAL_TRIALS research · 2018-06-06Clinical Trial Update: PAIR Study-PAP And IOP Relationship: Study 2
This clinical trial update notes the completion of PAIR Study 2, which investigates the relationship between PAP therapy and intraocular pre…
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CLINICAL_TRIALS research · 2017-10-24Clinical Trial Update: LSFG in Patients With Normal Tension Glaucoma Tension Glaucoma [NA]
Clinical trial update for LSFG in patients with normal tension glaucoma, with primary open-angle glaucoma listed among the conditions; the s…
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CLINICAL_TRIALS research · 2017-07-21Clinical Trial Update: Effectiveness and Safety of Adipose-Derived Regenerative Cells for Treatment of Glaucomatous Neurodegeneration [Phase 1, Phase 2]
A phase 1/2 clinical trial update evaluating adipose-derived regenerative cells for glaucomatous neurodegeneration, including retinal degene…
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CLINICAL_TRIALS research · 2017-07-21Clinical Trial Update: Exploratory Trial to Evaluate the Efficacy and Safety of D565H Twice Daily Versus D565 Once Daily [Phase 2]
An exploratory Phase 2 trial comparing D565H twice daily versus D565 once daily for open-angle glaucoma and ocular hypertension. The documen…
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CLINICAL_TRIALS research · 2017-04-04Clinical Trial Update: Metabolomics in Surgical Ophthalmological Patients
This is a clinical trial update about metabolomics in glaucoma surgery patients. Sponsored by Universitaire Ziekenhuizen KU Leuven, the stud…
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CLINICAL_TRIALS research · 2017-01-10Clinical Trial Update: The Expression of Matrix Metalloproteinase 13, Tissue Inhibitor of Metalloproteinases 3, and Calcium-sensing Receptor in Human Trabecular Meshwork [NA]
The study investigates expression levels of matrix metalloproteinase-13, tissue inhibitor of metalloproteinases-3, and calcium-sensing recep…
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CLINICAL_TRIALS research · 2016-12-12Clinical Trial Update: Surgical Approaches in Treating Uncontrolled Glaucoma in Black African and African-Caribbeans [NA]
A clinical trial update on surgical approaches to treat uncontrolled primary open-angle glaucoma in Black African and African-Caribbean popu…
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CLINICAL_TRIALS research · 2016-11-18Clinical Trial Update: A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension [Phase 3]
A Phase 3 clinical trial of a glaucoma therapy for open-angle glaucoma and ocular hypertension conducted by Alcon Research has completed.
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CLINICAL_TRIALS research · 2016-02-17Clinical Trial Update: Following Patients After Selective and Pascal Laser Trabeculoplasty for Treatment of Chronic Open-Angle Glaucoma
A clinical trial update reports on patients treated with selective and Pascal laser trabeculoplasty for chronic open-angle glaucoma; the stu…
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CLINICAL_TRIALS research · 2016-02-02Clinical Trial Update: Study to Compare Standard Perimetry With the New Scotoma-Oriented Perimetry (SCOPE) Using a New Fast German Adaptive Threshold Estimation (GATE) in Glaucoma Patients
A clinical trial comparing standard perimetry with scotoma-oriented perimetry (SCOPE) using a new fast German adaptive threshold estimation …
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CLINICAL_TRIALS research · 2015-10-08Clinical Trial Update: Functional Brain Changes of Primary Open-angle Glaucoma Patients
An update on a clinical trial studying functional brain changes in patients with primary open-angle glaucoma; the trial status is listed as …
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CLINICAL_TRIALS research · 2015-10-01Clinical Trial Update: RESEARCH PROTOCOL: Glaucoma Treatment Adherence and Persistence [NA]
This document outlines the protocol for a research study evaluating adherence and persistence in glaucoma treatment.
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CLINICAL_TRIALS research · 2015-05-29Clinical Trial Update: Study on the Oxygen Saturation in Pulsating and Non-pulsating Central Retinal Veins
This clinical trial update reports on a study evaluating oxygen saturation in pulsating versus non-pulsating central retinal veins in patien…
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CLINICAL_TRIALS research · 2015-04-08Clinical Trial Update: aICP in Glaucoma and Papilledema [NA]
This entry notes a clinical trial involving aICP for open-angle glaucoma and papilledema; the current trial status is unknown.
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CLINICAL_TRIALS research · 2015-02-05Clinical Trial Update: Posterior Cornea in Primary Open Angle Glaucoma
A clinical trial update evaluating the role of the posterior cornea in primary open-angle glaucoma; no results are reported in this update.
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CLINICAL_TRIALS research · 2014-12-17Clinical Trial Update: A Study of the VISION5 Product in Patients With Glaucoma or Ocular Hypertension [Phase 1]
Phase 1 clinical trial update for the VISION5 product in ocular hypertension and primary open-angle glaucoma. The study status is completed.
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CLINICAL_TRIALS research · 2014-12-09Clinical Trial Update: High Frequency Deep Sclerotomy (HFDS) ab Interno a Combination Surgical Intervention Using Cataract Surgery to Lower IOP [NA]
Clinical trial update describing High Frequency Deep Sclerotomy (HFDS) performed ab interno in combination with cataract surgery to lower in…
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CLINICAL_TRIALS research · 2013-12-12Clinical Trial Update: Early Diagnosis, Pathogenesis and Progression of Open Angle Glaucoma
This item provides a clinical trial update on early diagnosis, pathogenesis, and progression of open-angle glaucoma. The study includes Prim…
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CLINICAL_TRIALS research · 2013-06-25Clinical Trial Update: IOP Lowering Effect of PLT Versus SLT in Naiv OAG Patients [NA]
A clinical trial update comparing the IOP-lowering effects of PLT versus SLT in treatment-naive open-angle glaucoma patients; the study stat…
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CLINICAL_TRIALS research · 2013-02-20Clinical Trial Update: Correlation of Orbital Cerebrospinal Fluid Pressure and Retinal Venous Outflow in Primary Open-angle Glaucoma
This clinical trial update investigates the relationship between orbital cerebrospinal fluid pressure and retinal venous outflow in patients…