Oligoastrocytoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Evaluating the Expression Levels of MicroRNA-10b in Patients With Gliomas
The clinical trial investigating microRNA-10b expression in glioma patients has been terminated.
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma [Phase 2]
Phase 2 trial comparing proton beam therapy with intensity-modulated radiation therapy for preserving brain function in IDH-mutant grade II/…
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CLINICAL_TRIALS trial_result · 2024-11-22Clinical Trial Update: Safety and Efficacy of PD0332991 (Palbociclib), a Cyclin-dependent Kinase 4 and 6 Inhibitor, in Patients With Oligodendroglioma or Recurrent Oligoastrocytoma Anaplastic With the Activity of the Protein RB Preserved [Phase 2]
Phase 2 trial evaluating safety and efficacy of palbociclib (CDK4/6 inhibitor) in patients with oligodendroglioma or recurrent oligoastrocyt…
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CLINICAL_TRIALS trial_result · 2024-11-22Clinical Trial Update: Neo-adjuvant Evaluation of Glioma Lysate Vaccines in WHO Grade II Glioma [Phase 1]
Phase 1 trial evaluating neo-adjuvant glioma lysate vaccines in WHO Grade II glioma has completed.
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CLINICAL_TRIALS trial_result · 2024-06-14Clinical Trial Update: A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG) [Phase 1]
Phase 1 trial evaluating varlilumab in combination with the IMA950 vaccine and Poly-ICLC in adults with WHO grade II low-grade glioma; the s…
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CLINICAL_TRIALS trial_result · 2022-03-17Clinical Trial Update: Carboplatin, Melphalan, Etoposide Phosphate, Mannitol, and Sodium Thiosulfate in Treating Patients With Previously Treated Brain Tumors [Phase 1, Phase 2]
Phase 1/2 trial investigating a combination chemotherapy regimen (carboplatin, melphalan, etoposide phosphate, mannitol, and sodium thiosulf…
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CLINICAL_TRIALS trial_result · 2021-09-29Clinical Trial Update: Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas [Phase 1]
Phase 1 trial evaluating genetically modified neural stem cells with flucytosine and leucovorin for recurrent high-grade gliomas; results co…
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CLINICAL_TRIALS trial_result · 2021-02-15Clinical Trial Update: Primary Chemotherapy by BCNU-TMZ Combination in Newly Diagnosed Anaplastic Oligodendrocytic Tumors: Phase II Trial With Translational Molecular Analysis [Phase 2]
Phase II trial evaluating primary chemotherapy with a BCNU-TMZ combination in newly diagnosed oligodendroglial tumors with translational mol…
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CLINICAL_TRIALS trial_result · 2020-11-04Clinical Trial Update: Vaccine for Patients With Newly Diagnosed or Recurrent Low-Grade Glioma [Phase 2]
Phase 2 clinical trial update for a vaccine in newly diagnosed or recurrent low-grade glioma, with completed status and results posted.
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: (11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas
A clinical trial evaluating the PET tracer 11C-dLop as a marker of P-glycoprotein function in gliomas was terminated. The study enrolled pat…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases [Phase 1]
This Phase 1 trial assessing bafetinib in adults with recurrent high-grade glioma or brain metastases has completed.
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CLINICAL_TRIALS trial_result · 2016-10-21Clinical Trial Update: Evaluation of FDOPA-PET/MRI in Pediatric Patients With CNS Tumors [Phase 1]
Phase 1 trial evaluating FDOPA-PET/MRI imaging in pediatric CNS tumors has completed the Phase 1 portion.
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CLINICAL_TRIALS trial_result · 2016-02-29Clinical Trial Update: Sunitinib in Treating Patients With Recurrent Malignant Gliomas [Phase 2]
Phase 2 trial evaluating sunitinib for adults with recurrent malignant gliomas has completed; results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2015-12-08Clinical Trial Update: HLA-A2-Restricted Glioma Antigen-Peptides Vaccinations With Poly-ICLC for Recurrent WHO Grade II Gliomas [EARLY_Phase 1]
An early Phase 1 trial evaluating an HLA-A2-restricted glioma antigen-peptide vaccine with Poly-ICLC in recurrent WHO Grade II gliomas (astr…
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Phase II Study of Carmustine, Streptozocin, and Mercaptopurine for Refractory or Recurrent Brain Neoplasms [Phase 2]
A Phase II trial of Carmustine, Streptozocin, and Mercaptopurine for refractory or recurrent brain neoplasms has completed.
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CLINICAL_TRIALS trial_result · 2015-03-18Clinical Trial Update: Natural History of Brain Function, Quality of Life, and Seizure Control in Patients With Brain Tumor Who Have Undergone Surgery
This completed clinical trial examined the natural history of brain function, quality of life, and seizure control in adults with brain tumo…
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma [Phase 1]
Phase 1 trial evaluating high-dose vorinostat with fractionated SBRT in patients with recurrent glioma; the study has been terminated.
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CLINICAL_TRIALS trial_result · 2014-11-14Clinical Trial Update: Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma [Phase 1, Phase 2]
The clinical trial evaluating interstitial infusion of IL13-PE38QQR cytotoxin in recurrent malignant glioma has completed Phase 1 and Phase …
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CLINICAL_TRIALS trial_result · 2014-08-05Clinical Trial Update: Treatment Strategy for Low-grade Gliomas [Phase 3]
A Phase 3 trial for low-grade gliomas has been terminated, involving astrocytoma, oligodendroglioma, and oligoastrocytoma.
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CLINICAL_TRIALS trial_result · 2013-02-07Clinical Trial Update: RO4929097 in Treating Patients With Recurrent Invasive Gliomas [Phase 1]
Phase 1 trial update for RO4929097 in recurrent invasive gliomas has been terminated.
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CLINICAL_TRIALS trial_result · 2012-02-09Clinical Trial Update: A Phase II Study of Temozolomide and O6-Benzylguanine (O6-BG) in Patients With Temozolomide-Resistant Anaplastic Glioma [Phase 2]
This Phase II study evaluating temozolomide in combination with O6-benzylguanine for temozolomide-resistant anaplastic glioma was terminated…
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CLINICAL_TRIALS trial_result · 2011-12-09Clinical Trial Update: Phase II Study of Irinotecan HCI for Recurrent Anaplastic Astrocytomas, Mixed Malignant Gliomas, and Oligodendrogliomas [Phase 2]
Phase II trial of irinotecan hydrochloride in recurrent anaplastic astrocytoma, mixed malignant glioma, and oligodendroglioma was terminated…
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CLINICAL_TRIALS trial_result · 2011-07-04Clinical Trial Update: IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma [Phase 1]
Phase 1 trial evaluating IL13-PE38QQR infusion after surgical resection, followed by radiation therapy with or without temozolomide, in pati…
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CLINICAL_TRIALS trial_result · 2011-06-06Clinical Trial Update: Histologic Effect/Safety of Pre/Post-Operative IL13-PE38QQR in Recurrent Resectable Supratentorial Malignant Glioma Patients [Phase 1]
A completed Phase 1 trial assessed histologic effects and safety of pre/post-operative IL13-PE38QQR in patients with recurrent resectable su…
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CLINICAL_TRIALS trial_result · 2011-06-06Clinical Trial Update: Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma [Phase 1]
Phase 1 imaging study evaluating how the IL13-PE38QQR conjugate distributes in adult patients with recurrent malignant glioma before and aft…