Obesity
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Motivating to Exercise and Diet, and Educating to Healthy Behaviors After Breast Cancer [NA]
A completed clinical trial tested strategies to motivate overweight or obese breast cancer patients to exercise, follow a healthier diet, an…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Pancreatic Polypeptide as a Modulator of Amylin- Induced Satiety in Healthy Humans [NA]
A recruiting ClinicalTrials.gov study at University Hospital Gentofte investigates pancreatic polypeptide as a modulator of amylin-induced s…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: MIST (Metabolic Intervention With Semaglutide and THR-β Therapy) Trial [Phase 2]
The Phase 2 MIST trial evaluating metabolic intervention with semaglutide and THR-β therapy for adult obesity is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Setmelanotide to Treat Obesity in a Patient With Pseudohypoparathyroidism Type 1a (PHP1a) [Phase 2]
A Phase 2 trial is evaluating setmelanotide for obesity in patients with pseudohypoparathyroidism type 1a; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/Obesity [Phase 2]
Phase 2 clinical trial assessing MOTS-c to improve insulin sensitivity in adults with prediabetes and overweight/obesity is currently recrui…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Perception of Quality of Life in Patients Undergoing Endoscopic Vertical Gastroplasty [NA]
Clinical trial update evaluating perceived quality of life in participants undergoing endoscopic vertical gastroplasty for obesity; the stud…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Reducing Obesity Using Social Ties Program [NA]
A clinical trial to test whether a social ties-based program can reduce obesity is recruiting. It is sponsored by Weill Medical College of C…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Effect of Naltrexone Hydrochloride ER and Bupropion Hydrochloride ER Combination (Contrave®/Mysimba®) on Major Adverse Cardiovascular Events (MACE) [Phase 4]
Phase 4 trial update on whether the naltrexone ER and bupropion ER combination (Contrave/Mysimba) influences major adverse cardiovascular ev…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: A Research Study of the New Medicine NNC0519-0130 in Male Chinese Participants Living With Excess Body Weight [Phase 1]
Phase 1 study of NNC0519-0130 in male Chinese participants living with excess body weight has completed.
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: A Drug Drug Interaction Study to Evaluate the Effect of VCT220 on the Pharmacokinetics of Repaglinide, Rosuvastatin, and Digoxin in Healthy, Overweight, and Obese Subjects [Phase 1]
Phase 1 trial assessing how VCT220 affects the pharmacokinetics of repaglinide, rosuvastatin, and digoxin in healthy overweight and obese su…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Effect of Short-Term Beta-Cell Rest in Adolescents and Young Adults With Type 2 Diabetes Mellitus
NIDDK-sponsored trial update reporting on the completed study of a short-term beta-cell rest intervention in adolescents and young adults wi…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Alliance of Randomized Trials of Medicine vs Metabolic Surgery in Type 2 Diabetes
An update on a randomized trial comparing medical therapy against metabolic surgery for type 2 diabetes mellitus and obesity, with the study…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Metformin for Antipsychotic-induced Weight Gain in Adults With Intellectual Disability [Phase 4]
A Phase 4 clinical trial is evaluating metformin to address antipsychotic-induced weight gain in adults with intellectual disability and is …
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Effects of Physical Exercise and a Nutritional Supplement on Body Composition, Metabolic Function, and Overall Health in Adults With a Metabolically Challenging Profile [NA]
This clinical trial update describes a study evaluating the combined effects of structured physical exercise and a nutritional supplement on…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Inter-relationships Among Glucose, Brain, Gut Microbiota and MicroRNAs (IRONmiRNA).
The IRONmiRNA clinical trial investigates how glucose regulation interacts with brain activity, gut microbiota, and microRNAs in obesity. Th…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss [Phase 3]
A Phase 3 study (AMAZE 12) is evaluating the investigational drug NNC0487-0111 for helping people with obesity maintain weight loss; the tri…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Stay In Treatment for Pediatric Weight Management [NA]
A clinical trial update indicates that the Wake Forest University Health Sciences pediatric weight management study has completed.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Adipose Tissue Gene Expression and Metabolomics Links to the Gut Microbiome-brain Axis
A clinical trial investigating how adipose tissue gene expression and metabolomics relate to the gut microbiome-brain axis in obesity. The s…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Obesity Cohort Bichat Louis Mourier
Trial update for the Obesity Cohort at Bichat Louis Mourier; the study status is COMPLETED.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Diet Order Effects of Low Fat vs. Low Carb Diets on Body Fat Change [NA]
This clinical trial update from NIDDK examines the effects of low-fat versus low-carbohydrate diets on body fat in adults who are overweight…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Effects of Diet Changes on Metabolism
This completed clinical trial examines how changes in diet influence metabolism in people with obesity.
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: The Bennett Kids PowerUP Project [NA]
The Bennett Kids PowerUP Project trial, sponsored by Wake Forest University Health Sciences, has completed its study investigating obesity i…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Non-invasive Tests for Non-alcoholic Steato-hepatitis [NA]
This document reports an update on a clinical trial evaluating non-invasive tests for non-alcoholic steatohepatitis (NASH) with fibrosis, in…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Involvement of the Gut Microbiota-brain Cross-talk in the Loss of Eating Control
A clinical trial is recruiting to study how gut microbiota-brain cross-talk may influence loss of eating control in people with obesity.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Real-world Effectiveness and Dosing Patterns of Tirzepatide in People With Obesity
A clinical trial update on tirzepatide for obesity, examining real-world effectiveness and dosing patterns; the study is sponsored by Radbou…