Obesity

• CLINICAL_TRIALS trial_result · 2025-12-18
  Clinical Trial Update: Effects of AZD5004 in Adults Who Are Living With Obesity or Overweight With at Least 1 Weight-related Comorbidity [Phase 2]

  Phase 2 clinical trial update on AZD5004 in adults with obesity or overweight and at least one weight-related comorbidity; the study status …

• CLINICAL_TRIALS trial_result · 2025-12-18
  Clinical Trial Update: A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASC47 in Combination With Semaglutide [Phase 1]

  Phase 1 study evaluating safety, tolerability, pharmacokinetics, and pharmacodynamics of ASC47 in combination with semaglutide for chronic w…

• CLINICAL_TRIALS trial_result · 2025-12-18
  Clinical Trial Update: FIT-COACH: Fitbit Intervention With Coordinated Health Coaching and PCP Support [NA]

  Clinical trial update for FIT-COACH, a Fitbit-based lifestyle intervention with health coaching and primary care support, which has complete…

• CLINICAL_TRIALS trial_result · 2025-12-18
  Clinical Trial Update: Role of the Microbiota in Obesity: Effect After Bariatric Surgery [NA]

  A completed clinical trial examining how the gut microbiota influences obesity outcomes after bariatric surgery.

• CLINICAL_TRIALS trial_result · 2025-12-18
  Clinical Trial Update: Cognitive Behavioral Therapy for Adolescents With Bulimia Nervosa and Higher Weight (Online Treatment Study) [NA]

  This clinical trial update notes the completion of an online cognitive behavioral therapy program for adolescents with bulimia nervosa who a…

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• CLINICAL_TRIALS trial_result · 2025-12-17
  Clinical Trial Update: Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Maintenance Treatment [Phase 3]

  Phase 3 maintenance trial evaluating cognitive-behavioral therapy combined with lisdexamfetamine (LDX) for binge-eating disorder and obesity…

• CLINICAL_TRIALS trial_result · 2025-12-17
  Clinical Trial Update: Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Medication Change for Non-Responders [Phase 2, Phase 3]

  A Phase 2/3 clinical trial update reports a medication change for non-responders in a cognitive-behavioral plus pharmacologic treatment appr…

• CLINICAL_TRIALS trial_result · 2025-12-17
  Clinical Trial Update: Efficacy and Safety of Maridebart Cafraglutide in Adult Participants in Japan Who Have Obesity Disease [Phase 3]

  Phase 3 clinical trial update on the efficacy and safety of Maridebart Cafraglutide for obesity in adults in Japan; the study is currently n…

• CLINICAL_TRIALS trial_result · 2025-12-17
  Clinical Trial Update: CARE Trial: Comparing Different Levels of Calorie Reduction for Weight Loss [NA]

  A completed clinical trial (CARE trial) comparing different levels of daily calorie reduction for weight loss. It is sponsored by the Univer…

• CLINICAL_TRIALS trial_result · 2025-12-17
  Clinical Trial Update: Effectiveness and Cost-Effectiveness of Fully-Automated Digital vs. Human Coach-Based Diabetes Prevention Programs [NA]

  A completed clinical trial compares a fully automated digital diabetes prevention program with a human coach-based program, evaluating effec…

• CLINICAL_TRIALS trial_result · 2025-12-17
  Clinical Trial Update: Partnership Optimizes Weight Management in Primary Care [NA]

  This clinical trial update reports the completion of a University of Alabama at Birmingham study focused on optimizing weight management in …

• CLINICAL_TRIALS trial_result · 2025-12-17
  Clinical Trial Update: Changes in Muscle Strength, Inflammatory Markers, and Body Composition in Response to Alternate Day Fasting Combined With Krill Oil Supplementation in Adults With Overweight and Obesity [NA]

  This completed trial evaluated the effects of alternate day fasting combined with krill oil supplementation on muscle strength, inflammatory…

• CLINICAL_TRIALS trial_result · 2025-12-17
  Clinical Trial Update: Timing of Sodium Intake and Nocturnal Sodium Excretion and Blood Pressure in Obese African Americans [NA]

  A completed clinical trial evaluated how the timing of sodium intake influences nocturnal sodium excretion and blood pressure in obese Afric…

• CLINICAL_TRIALS trial_result · 2025-12-17
  Clinical Trial Update: FoodRx for Obesity Treatment [NA]

  A completed clinical trial evaluating FoodRx as a treatment for obesity, with results posted.

• CLINICAL_TRIALS trial_result · 2025-12-16
  Clinical Trial Update: Safety and Tolerability Evaluationof Phascolarcobacterium Faecium [Phase 1]

  Phase 1 safety and tolerability evaluation of Phascolarcobacterium Faecium has completed, reporting initial safety data in early-stage testi…

• CLINICAL_TRIALS trial_result · 2025-12-16
  Clinical Trial Update: Phase Ia Clinical Study of HDM1005 Injection [Phase 1]

  This document reports the completion of a Phase Ia clinical study of the HDM1005 Injection for obesity and overweight. No efficacy data is p…

• CLINICAL_TRIALS trial_result · 2025-12-16
  Clinical Trial Update: Phase Ib Clinical Study of HDM1005 Injection [Phase 1]

  This document notes the completion of the Phase 1 portion of a Phase Ib study of the HDM1005 injection for overweight and obesity.

• CLINICAL_TRIALS trial_result · 2025-12-16
  Clinical Trial Update: Advanced Strategy of Food Supplements for the Optimization of Satiety and Lipid Metabolism in Maturity (SACIANS) [NA]

  A completed clinical trial from the University of Alicante assessing a food supplement strategy (SACIANS) to optimize satiety and lipid meta…

• CLINICAL_TRIALS trial_result · 2025-12-15
  Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, and Tolerability in Participants With Obesity or Overweight With Weight-Related Comorbidities [Phase 2]

  Phase 2 study sponsored by Ascletis Pharma evaluated a drug candidate for obesity and weight-related comorbidities, assessing efficacy, safe…

• CLINICAL_TRIALS trial_result · 2025-12-15
  Clinical Trial Update: Effect of Education Given With Virtual Reality Glasses on Self-Care Ability of Patients After Bariatric Surgery [NA]

  A completed clinical trial evaluated whether education delivered with virtual reality glasses improves self-care ability in bariatric surger…

• CLINICAL_TRIALS trial_result · 2025-12-12
  Clinical Trial Update: A Study to Test Whether Survodutide Helps Japanese People Living With Obesity Disease [Phase 3]

  A Phase 3 clinical trial to evaluate whether Survodutide helps Japanese people living with obesity has completed.

• CLINICAL_TRIALS trial_result · 2025-12-12
  Clinical Trial Update: Longitudinal Retrospective Analysis of Prospectively Collected Data for Outcomes After Primary Sleeve Gastrectomy (N=20 000) in the Swedish National Quality Registry SOReg (Scandinavian Obesity Surgery Registry)

  A large longitudinal retrospective analysis of prospectively collected data from the Swedish SOReg registry examines outcomes after primary …

• CLINICAL_TRIALS trial_result · 2025-12-12
  Clinical Trial Update: A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Combined Versus Separate Injections in People With Overweight or Obesity [Phase 1]

  A Phase 1 study comparing blood levels of cagrilintide and semaglutide after combined versus separate injections in adults with overweight o…

• CLINICAL_TRIALS trial_result · 2025-12-12
  Clinical Trial Update: Randomized Trial of a Healthy Weight Intervention for Youth With Serious Emotional Disturbance [NA]

  A randomized trial evaluated a healthy weight intervention for youth with serious emotional disturbance, and the study has completed.

• CLINICAL_TRIALS trial_result · 2025-12-11
  Clinical Trial Update: MitoQ for the Treatment of Metabolic Dysfunction in Asthma [Phase 1]

  Phase 1 results are posted for a study of MitoQ in metabolic dysfunction associated with asthma. The trial is sponsored by the University of…