Nonalcoholic Steatohepatitis
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CLINICAL_TRIALS trial_result · 2015-11-30Clinical Trial Update: Endoscopic Ultrasound(EUS)-Guided TRUCUT Biopsy (EUS-TCB) of Suspected Nonalcoholic Fatty Liver Disease(NAFLD.) [NA]
This update reports the completion of a trial evaluating endoscopic ultrasound-guided TRUCUT biopsy for suspected nonalcoholic fatty liver d…
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CLINICAL_TRIALS trial_result · 2015-10-07Clinical Trial Update: Anti-Fibrotic Effects of Losartan In Nash Evaluation Study [Phase 3]
Phase 3 study evaluating losartan for anti-fibrotic effects in nonalcoholic steatohepatitis has completed.
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CLINICAL_TRIALS trial_result · 2015-08-21Clinical Trial Update: The Farnesoid X Receptor (FXR) Ligand Obeticholic Acid in NASH Treatment Trial(FLINT) [Phase 2]
Phase 2 FLINT trial of obeticholic acid for nonalcoholic fatty liver disease and nonalcoholic steatohepatitis reported results, showing hist…
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CLINICAL_TRIALS trial_result · 2015-05-29Clinical Trial Update: Omega 3 Fish Oil Supplements vs. Placebo for Patients With Non-alcoholic Steatohepatitis (NASH) [Phase 2, Phase 3]
A completed Phase 2/3 clinical trial evaluating omega-3 fish oil supplements versus placebo in patients with nonalcoholic steatohepatitis an…
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CLINICAL_TRIALS trial_result · 2015-05-25Clinical Trial Update: Default Mode Network fMRI Maps as a Predictive Index of Hepatic Encephalopathy Outcome
Completed clinical trial evaluating whether resting-state default mode network fMRI maps can predict outcomes in hepatic encephalopathy rela…
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CLINICAL_TRIALS trial_result · 2015-04-08Clinical Trial Update: Betaine in Patients With Nonalcoholic Steatohepatitis [Phase 2]
This clinical trial update reports the completion of a Phase 2 study of betaine in patients with nonalcoholic steatohepatitis.
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CLINICAL_TRIALS trial_result · 2014-09-09Clinical Trial Update: Pentoxifylline/Nonalcoholic Steatohepatitis (NASH) Study: The Effect of Pentoxifylline on NASH [Phase 2, Phase 3]
This entry reports that a Phase 2/Phase 3 clinical trial evaluating pentoxifylline for nonalcoholic steatohepatitis has completed, with resu…
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CLINICAL_TRIALS trial_result · 2014-08-27Clinical Trial Update: Study of Liraglutide Versus Insulin on Liver Fat Fraction in Patients With Type 2 Diabetes [Phase 2]
Phase 2 trial comparing liraglutide to insulin in patients with type 2 diabetes to assess liver fat fraction in nonalcoholic fatty liver dis…
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CLINICAL_TRIALS trial_result · 2014-05-16Clinical Trial Update: Efficacy of Rifaximin on Hepatosteatosis and Steatohepatitis Patients [NA]
A completed clinical trial evaluated the efficacy of rifaximin in patients with hepatosteatosis (fatty liver) and steatohepatitis.
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CLINICAL_TRIALS trial_result · 2014-02-24Clinical Trial Update: Trial of Hepaguard® in Adults With Nonalcoholic Steatohepatitis [NA]
ClinicalTrials.gov entry indicates the Hepaguard trial in adults with nonalcoholic fatty liver disease/nonalcoholic steatohepatitis has comp…
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CLINICAL_TRIALS trial_result · 2014-02-04Clinical Trial Update: Safety, Tolerability, Pharmacokinetics and Activity of GS-9450 in Adults With Non-Alcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 trial evaluating safety, tolerability, pharmacokinetics and activity of GS-9450 in adults with nonalcoholic steatohepatitis has been…
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CLINICAL_TRIALS trial_result · 2014-01-09Clinical Trial Update: The Effects of Resveratrol Supplement on Biochemical Factors and Hepatic Fibrosis in Patients With Nonalcoholic Steatohepatitis [Phase 2, Phase 3]
This clinical trial update reports on the effects of resveratrol supplementation on biochemical factors and hepatic fibrosis in patients wit…
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CLINICAL_TRIALS trial_result · 2013-09-26Clinical Trial Update: Pentoxifylline in Patients With Nonalcoholic Steatohepatitis [Phase 2]
A Phase 2 clinical trial evaluating pentoxifylline in nonalcoholic steatohepatitis has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2013-07-24Clinical Trial Update: Fish Oil and Diet for the Treatment of Non-Alcoholic Steatohepatitis (NASH) [Phase 2]
A Phase 2 trial evaluating fish oil (omega-3 fatty acids) and diet for nonalcoholic steatohepatitis (NASH) and hepatic steatosis was termina…
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CLINICAL_TRIALS trial_result · 2013-02-15Clinical Trial Update: The Effects of Synbiotics Supplement on Biochemical Factors and Hepatic Fibrosis in Patients With Nonalcoholic Steatohepatitis [Phase 2, Phase 3]
This update reports results from Phase 2 and Phase 3 trials evaluating a synbiotic supplement's impact on biochemical factors and hepatic fi…
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CLINICAL_TRIALS trial_result · 2012-10-11Clinical Trial Update: Effects of Alanine in Patients With Nonalcoholic Steatohepatitis [NA]
This clinical trial update notes that a study evaluating the effects of alanine in patients with nonalcoholic steatohepatitis has been compl…
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CLINICAL_TRIALS trial_result · 2012-08-29Clinical Trial Update: Glucose-induced Glucagon-like Peptide 1 (GLP-1) Secretion in NAFLD Patients Compared to Healthy Controls
A completed clinical trial evaluating glucose-induced GLP-1 secretion in patients with NAFLD/NASH compared with healthy controls.
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CLINICAL_TRIALS trial_result · 2012-08-01Clinical Trial Update: Pioglitazone vs Vitamin E vs Placebo for Treatment of Non-Diabetic Patients With Nonalcoholic Steatohepatitis (PIVENS) [Phase 3]
This document reports results from the Phase 3 PIVENS trial comparing pioglitazone, vitamin E, and placebo for non-diabetic patients with no…
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CLINICAL_TRIALS trial_result · 2012-04-26Clinical Trial Update: Efficacy and Safety of Diamel in Patients With Nonalcoholic Steatohepatitis [Phase 3]
Phase 3 clinical trial update assessing the efficacy and safety of Diamel in patients with nonalcoholic steatohepatitis and insulin resistan…
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CLINICAL_TRIALS trial_result · 2012-01-31Clinical Trial Update: Study of Aramchol in Patients With Fatty Liver Disease or Nonalcoholic Steatohepatitis [Phase 2]
Phase 2 study of Aramchol in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis has completed.
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CLINICAL_TRIALS trial_result · 2012-01-20Clinical Trial Update: Effect of Spironolactone and Vitamin E in Patients With Nonalcoholic Fatty Liver Disease [Phase 2]
Phase 2 trial evaluating spironolactone and vitamin E for nonalcoholic fatty liver disease has completed.
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CLINICAL_TRIALS trial_result · 2011-07-20Clinical Trial Update: Treating Nonalcoholic Steatohepatitis (NASH) With Metformin [Phase 2]
A Phase 2 trial evaluating metformin for nonalcoholic steatohepatitis (NASH) was completed and results were posted.
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CLINICAL_TRIALS trial_result · 2011-06-23Clinical Trial Update: Safety and Efficacy of Oral Administration of Anti-CD3 Monoclonal Antibody (mAb)in Patients With the Metabolic Syndrome [Phase 2]
A Phase 2 trial evaluating the safety and efficacy of an orally administered anti-CD3 monoclonal antibody in patients with nonalcoholic stea…
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CLINICAL_TRIALS trial_result · 2011-04-05Clinical Trial Update: Treating Nonalcoholic Steatohepatitis With Pioglitazone [Phase 2]
A Phase 2 clinical trial evaluated pioglitazone for treating nonalcoholic steatohepatitis (NASH); the study completed and results were poste…
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CLINICAL_TRIALS trial_result · 2010-09-24Clinical Trial Update: Effects of Exenatide (Byetta®) on Liver Function in Patients With Nonalcoholic Steatohepatitis (NASH) [Phase 4]
Phase 4 trial results assess the effects of exenatide (Byetta) on liver function in patients with nonalcoholic steatohepatitis (NASH); the s…