Nonalcoholic Steatohepatitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-02-03Clinical Trial Update: Safety and Tolerability of Novel Medical Nutrition Products for NAFLD Treatment [Phase 2, Phase 3]
Phase 2/3 clinical trial update assessing safety and tolerability of novel medical nutrition products for NAFLD/NASH treatment.
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Study to Evaluate the Pharmacokinetics of Firsocostat or Fenofibrate in Adults With Normal and Impaired Hepatic Function [Phase 1]
Phase 1 pharmacokinetics study evaluating firsocostat or fenofibrate in adults with normal and impaired hepatic function; completed with res…
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CLINICAL_TRIALS trial_result · 2020-12-03Clinical Trial Update: Study to Evaluate the Safety and Efficacy of Selonsertib, Firsocostat, Cilofexor, and Combinations in Participants With Bridging Fibrosis or Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 trial evaluating multiple drugs (Selonsertib, Firsocostat, Cilofexor, and combinations) for bridging fibrosis or compensated cirrhos…
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CLINICAL_TRIALS trial_result · 2020-11-24Clinical Trial Update: CLINICAL PROTOCOL to Investigate the Long-term Safety and Efficacy of Metreleptin in Various Forms of Partial Lipodystrophy [Phase 2]
Phase 2 clinical protocol update assessing long-term safety and efficacy of metreleptin in various forms of partial lipodystrophy; study sta…
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CLINICAL_TRIALS trial_result · 2020-10-14Clinical Trial Update: Safety and Tolerability of HepaStem in Patients With Cirrhotic and Pre-cirrhotic NASH Patients [Phase 1, Phase 2]
Clinical trial updates on HepaStem show safety and tolerability in patients with cirrhotic and pre-cirrhotic nonalcoholic steatohepatitis (N…
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CLINICAL_TRIALS trial_result · 2020-10-12Clinical Trial Update: Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GS-9674 (Cilofexor), and the Effect of Food on GS-9674 Pharmacokinetics and Pharmacodynamics [Phase 1]
Phase 1 study evaluating safety, tolerability, PK/PD of GS-9674 (cilofexor) and effect of food on PK/PD in healthy volunteers; completed wit…
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CLINICAL_TRIALS trial_result · 2020-09-30Clinical Trial Update: Pharmacokinetics and Pharmacodynamics of Cilofexor in Adults With Normal and Impaired Hepatic Function [Phase 1]
Phase 1 study reporting pharmacokinetics and pharmacodynamics of cilofexor in adults with normal and impaired hepatic function; completed wi…
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CLINICAL_TRIALS trial_result · 2020-09-28Clinical Trial Update: Clinical Trial to Evaluate Efficacy of GR-MD-02 for Treatment of Liver Fibrosis in Patients With NASH With Advanced Fibrosis [Phase 2]
Phase 2 trial evaluating GR-MD-02 for liver fibrosis in NASH with advanced fibrosis has completed successfully and posted results.
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CLINICAL_TRIALS trial_result · 2020-09-04Clinical Trial Update: Rifaximin in Fatty Liver Disease [Phase 4]
Phase 4 trial of rifaximin for fatty liver disease was terminated; results posted but status terminated.
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CLINICAL_TRIALS trial_result · 2020-09-04Clinical Trial Update: Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-14
A completed clinical trial update for a companion protocol related to the Methacetin Breath Test in the Conatus protocol; results posted in …
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CLINICAL_TRIALS trial_result · 2020-08-17Clinical Trial Update: Study of Gemcabene in Adults With FPLD [Phase 1, Phase 2]
Phase 1/2 trial updates for gemcabene in adults with familial partial lipodystrophy (FPLD) and hypertriglyceridemia have been completed with…
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CLINICAL_TRIALS trial_result · 2020-07-24Clinical Trial Update: Study to Evaluate Safety, Tolerability, and Efficacy of GS-0976 in Adults With Nonalcoholic Steatohepatitis [Phase 2]
Phase 2 trial update for GS-0976 in adults with nonalcoholic steatohepatitis (NASH) completed with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-07-23Clinical Trial Update: The Efficacy and Safety of Pioglitazone in Patients With Nonalcoholic Steatohepatitis [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of pioglitazone in patients with nonalcoholic steatohepatitis (NASH).
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CLINICAL_TRIALS trial_result · 2020-07-21Clinical Trial Update: Colesevelam Versus Placebo in the Treatment of Nonalcoholic Steatohepatitis [Phase 2]
A Phase 2 trial comparing colesevelam to placebo in nonalcoholic steatohepatitis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-06-29Clinical Trial Update: Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis [Phase 3]
Phase 3 trial of Selonsertib for nonalcoholic steatohepatitis (NASH) with bridging fibrosis (F3) was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-05-07Clinical Trial Update: Safety and Efficacy of Selonsertib in Adults With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) [Phase 3]
Phase 3 trial evaluating safety and efficacy of selonsertib in adults with compensated cirrhosis due to nonalcoholic steatohepatitis (NASH) …
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CLINICAL_TRIALS trial_result · 2020-03-10Clinical Trial Update: Phase 2a, Dose-ranging Study With PF-05221304 in Nonalcoholic Fatty Liver Disease (NAFLD) [Phase 2]
Phase 2a dose-ranging study of PF-05221304 in nonalcoholic fatty liver disease/nonalcoholic steatohepatitis completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: Tesamorelin Effects on Liver Fat and Histology in HIV [NA]
Clinical trial update reporting on tesamorelin effects on liver fat and histology in HIV patients with NAFLD/NASH; study completed with resu…
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CLINICAL_TRIALS trial_result · 2019-11-22Clinical Trial Update: Palliative Care for Non-Malignant Diseases (COMPASS Trial) [NA]
Clinical trial update for the COMPASS trial on palliative care in non-malignant liver diseases, terminated with posted results in 2019.
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CLINICAL_TRIALS trial_result · 2019-06-25Clinical Trial Update: Researching an Effect of GLP-1 Agonist on Liver STeatosis (REALIST) [Phase 4]
A Phase 4 trial investigating the effect of a GLP-1 agonist on liver steatosis in adults with type 2 diabetes and nonalcoholic steatohepatit…
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CLINICAL_TRIALS trial_result · 2019-05-10Clinical Trial Update: Efficacy and Safety Study of Cenicriviroc for the Treatment of Nonalcoholic Steatohepatitis (NASH) in Adult Participants With Liver Fibrosis [Phase 2]
Phase 2 trial assessing cenicriviroc for nonalcoholic steatohepatitis with liver fibrosis completed; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-01-29Clinical Trial Update: Evaluating the Safety, Tolerability, and Efficacy of GS-9674 in Participants With Nonalcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 trial evaluating the safety, tolerability, and efficacy of cilofexor (GS-9674) in nonalcoholic steatohepatitis has completed with re…
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CLINICAL_TRIALS trial_result · 2019-01-07Clinical Trial Update: JKB-121 for the Treatment of Nonalcoholic Steatohepatitis [Phase 2]
Phase 2 clinical trial update for JKB-121 in nonalcoholic steatohepatitis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-09-11Clinical Trial Update: Prevalence of Non-alcoholic Fatty Liver Disease (NAFLD) in Hispanics With Diabetes Mellitus Type 2 (T2DM) and Role of Treatment [Phase 4]
Phase 4 clinical trial update on prevalence of NAFLD/Nonalcoholic Steatohepatitis in Hispanics with type 2 diabetes and the role of treatmen…
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CLINICAL_TRIALS trial_result · 2018-07-17Clinical Trial Update: Hydroxytyrosol and Vitamin E in Pediatric NASH [Phase 3]
Phase 3 pediatric trial assessing hydroxytyrosol and vitamin E for nonalcoholic fatty liver disease (NAFLD) / nonalcoholic steatohepatitis (…