Nonalcoholic Fatty Liver Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS other · 2024-09-19Clinical Trial Update: Metabolic Syndrome and Fatty Liver Disease Among Egyptian Patients with Chronic HBV
A clinical trial update from Assiut University describes a study evaluating metabolic syndrome and fatty liver disease in Egyptian patients …
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Identification of Fatty Liver With Advanced Fibrosis in Type 2 Diabetes Using Simple Fibrosis Scores and Electronic Reminder Messages [NA]
This completed clinical trial evaluated simple fibrosis scoring methods and electronic reminder messages to identify nonalcoholic fatty live…
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CLINICAL_TRIALS research · 2024-08-06Clinical Trial Update: Quantification of Hepatic Steatosis With Different Ultrasound Frequency
This clinical trial update describes a study on quantifying hepatic steatosis using ultrasound at different frequencies; the trial is curren…
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CLINICAL_TRIALS research · 2024-08-05Clinical Trial Update: Ketogenic Diet in MASLD-related cACLD [NA]
Clinical trial evaluating a ketogenic diet for MASLD-related compensated advanced chronic liver disease; recruitment has not yet started.
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CLINICAL_TRIALS trial_result · 2024-07-12Clinical Trial Update: Prevalence of Steatosis and Steatohepatitis in Patients Undergoing Bariatric Surgery; a Biopsy-based Study
A completed biopsy-based study evaluates how common liver steatosis and nonalcoholic steatohepatitis are among patients undergoing bariatric…
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CLINICAL_TRIALS research · 2024-07-09Clinical Trial Update: Vigorous- Versus Moderate-intensity Exercise to Reduce Liver Fat in Adults With Obesity and NAFLD [NA]
A clinical trial comparing vigorous- versus moderate-intensity exercise to reduce liver fat in adults with obesity and nonalcoholic fatty li…
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CLINICAL_TRIALS research · 2024-06-26Clinical Trial Update: Gastric Bypass Stent Small-Sample-Size Study For Nonalcoholic Fatty Liver Disease [NA]
A small-sample-size clinical trial evaluating a gastric bypass stent for nonalcoholic fatty liver disease is currently recruiting.
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CLINICAL_TRIALS research · 2024-06-18Clinical Trial Update: HIBOC = Hepatic Imaging Biomarkers in Obese Children
A pediatric trial protocol investigating hepatic imaging biomarkers (elastography and related techniques) in obese children to assess liver …
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CLINICAL_TRIALS withdrawal · 2024-06-11Clinical Trial Update: A Study of BMN 255 in Participants With Non-Alcoholic Fatty Liver Disease And Hyperoxaluria [Phase 1]
BioMarin's BMN-255 Phase 1 trial in hyperoxaluria with nonalcoholic fatty liver disease has been withdrawn.
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CLINICAL_TRIALS research · 2024-06-10Clinical Trial Update: Effects of Growth Hormone Therapy on Metabolic Function in Fatty Liver Post-Pituitary Adenoma Surgery [Phase 4]
A Phase 4 clinical trial is evaluating whether growth hormone therapy improves metabolic function in fatty liver after pituitary adenoma sur…
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CLINICAL_TRIALS research · 2024-06-10Clinical Trial Update: Effect of Henagliflozein on Hepatic Fat Content in Patients With T2DM and NAFLD [Phase 4]
This clinical trial update describes an ongoing Phase 4 study evaluating Henagliflozein's effect on hepatic fat content in patients with typ…
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CLINICAL_TRIALS research · 2024-06-07Clinical Trial Update: Comparison of MRI-PDFF to TAEUS FLIP Device to Estimate Liver Fat Fraction in Adults
This clinical trial update compares MRI-PDFF with the TAEUS FLIP device for estimating liver fat fraction in adults with hepatic steatosis. …
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Liver and Fat Regulation in Overweight Adolescent Girls [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating liver fat regulation and weight-related outcomes in overweight adolescent girls has completed, with re…
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CLINICAL_TRIALS research · 2024-05-30Clinical Trial Update: Adiposity, Cardiometabolic and Neurocognitive Health Among Ethnic Groups: a Feasibility and Pilot Study
Feasibility and pilot study assessing adiposity, cardiometabolic health and neurocognitive function across ethnic groups. Recruitment is ong…
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CLINICAL_TRIALS trial_result · 2024-05-24Clinical Trial Update: Aspirin for the Treatment of Nonalcoholic Fatty Liver Disease [Phase 1, Phase 2]
Aspirin is being studied for nonalcoholic fatty liver disease and nonalcoholic steatohepatitis in Phase 1/2. The trial is completed, and res…
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CLINICAL_TRIALS research · 2024-05-22Clinical Trial Update: Clinical Study Evaluating the Safety and Efficacy of Esomeprazole in Treatment of Non-alcoholic Steatohepatitis [Phase 1, Phase 2]
Clinical trial evaluating the safety and efficacy of esomeprazole for non-alcoholic fatty liver disease and nonalcoholic steatohepatitis is …
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CLINICAL_TRIALS withdrawal · 2024-05-14Clinical Trial Update: A Prospective, Randomized, Placebo-Controlled Pilot Study to Characterize the Intestinal Microbiome and to Evaluate the Safety and Fecal Microbiome Changes Following Administration of Lyophilized PRIM-DJ2727 or Placebo Given Orally in Subjects With Nonalcoholic Fatty Liver Disease [Phase 2]
A Phase 2 randomized, placebo-controlled pilot study evaluating the safety and fecal microbiome changes after oral lyophilized PRIM-DJ2727 i…
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CLINICAL_TRIALS research · 2024-05-07Clinical Trial Update: The Relationship Between Fatty Liver and Breast Cancer
This clinical trial is examining the relationship between nonalcoholic fatty liver disease and breast cancer, and is currently recruiting pa…
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CLINICAL_TRIALS research · 2024-05-07Clinical Trial Update: Effect of Consumption of Millet Diet in Patients With NAFLD [NA]
A clinical trial is investigating the effects of a millet-based diet in patients with nonalcoholic fatty liver disease; the study is current…
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CLINICAL_TRIALS research · 2024-05-03Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Rencofilstat in Subjects With NASH and Advanced Liver Fibrosis [Phase 2]
A Phase 2 clinical trial update evaluating the efficacy and safety of Rencofilstat in subjects with nonalcoholic steatohepatitis and advance…
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CLINICAL_TRIALS trial_result · 2024-04-16Clinical Trial Update: Efficacy and Safety of Antiviral Therapy With Peg-interferon for Chronic Hepatitis B Complicated With Nonalcoholic Fatty Liver Disease（OCEAN PROJECT） [Phase 4]
Phase 4 clinical trial update evaluating the efficacy and safety of Peg-interferon antiviral therapy for chronic hepatitis B in patients wit…
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CLINICAL_TRIALS trial_result · 2024-04-09Clinical Trial Update: Study of HSK31679 in Subjects With Hypercholesterolemia With Nonalcoholic Fatty Liver Disease（NAFLD） [Phase 2]
Phase 2 trial of HSK31679 in adults with hypercholesterolemia completed.
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: A Multiple Ascending Dose Study of Pegozafermin in Participants With Biopsy Confirmed Nonalcoholic Steatohepatitis (NASH) or Nonalcoholic Fatty Liver Disease (NAFLD) and at High Risk of NASH [Phase 1, Phase 2]
A multiple ascending dose study of pegozafermin in participants with biopsy-confirmed NASH or NAFLD at high risk of NASH has completed phase…
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CLINICAL_TRIALS trial_result · 2024-01-24Clinical Trial Update: Ketohexokinase Inhibition in NAFLD [Phase 2]
Phase 2 clinical trial examining ketohexokinase inhibition for nonalcoholic fatty liver disease has completed.
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CLINICAL_TRIALS trial_result · 2024-01-17Clinical Trial Update: Amlexanox for Type 2 Diabetes and Obesity [Phase 2]
Phase 2 trial of amlexanox for type 2 diabetes mellitus and obesity was terminated, with results posted.