Nonalcoholic Fatty Liver Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-07-31Clinical Trial Update: A Trial to Learn if Receiving ALN-PNP siRNA is Safe and Well Tolerated, and How it Works in Adult Participants With Nonalcoholic Fatty Liver Disease (NAFLD) and a Genetic Risk Factor [Phase 1]
Phase 1 clinical trial update assessing safety, tolerability, and mechanism of ALN-PNP siRNA in adults with nonalcoholic fatty liver disease…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: The Impact of Pectin Supplementation on Systematic Inflammation Pathway, Gut Microbiome, and Metabolic Health in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) [NA]
ClinicalTrials.gov listing for a recruiting study evaluating the effects of pectin supplementation on systemic inflammation, the gut microbi…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Prevalence of NAFLD in T1DM Patients [NA]
A recruiting observational study from Ziekenhuis Oost-Limburg aims to determine how common nonalcoholic fatty liver disease is among people …
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Bariatric Embolization of Arteries for the Treatment of Nonalcoholic Steatohepatitis [NA]
This clinical trial update describes NCT02933554, evaluating bariatric embolization of arteries as a treatment for nonalcoholic steatohepati…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Liver Fat as a Dietary Target of the Chinese Medical Nutrition Therapy (CMNT) Diet for Treating Type 2 Diabetes With Nonalcoholic Fatty Liver Disease [NA]
A clinical trial is evaluating whether the CMNT Diet, by targeting liver fat, can improve treatment outcomes for people with type 2 diabetes…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Gepaktiv vs UDCA and Ademetionine in MAFLD With Hepatomegaly [NA]
A clinical study comparing Gepaktiv to ursodeoxycholic acid (UDCA) and ademetionine in metabolic dysfunction-associated fatty liver disease …
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity [NA]
Recruiting for a study on macrophage lysosomal lipid metabolism in obesity, exploring mechanisms that may influence obesity and related live…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Effect of Anti-osteoporotic Medications on Nonalcoholic Fatty Liver Disease [Phase 4]
This is a Phase 4 clinical trial evaluating whether anti-osteoporotic medications affect nonalcoholic fatty liver disease. The study is curr…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Digital Early Warning System for Acute Lung Injury in Liver Surgery
A ClinicalTrials.gov entry describing a study of a digital early warning system to detect acute lung injury in patients undergoing liver sur…
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CLINICAL_TRIALS trial_result · 2025-07-16Clinical Trial Update: Saroglitazar Magnesium 4 mg for Nonalcoholic Fatty Liver Disease (NAFLD) in People Living With HIV in the US [Phase 2]
A Phase 2 study of saroglitazar magnesium for nonalcoholic fatty liver disease in people living with HIV was terminated in the US, and resul…
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: Alternate Dosing Study of MK-6024 in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) (MK-6024-016) [Phase 2]
Merck's Phase 2 trial MK-6024-016 evaluating alternate dosing in adults with metabolic dysfunction-associated steatotic liver disease and no…
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CLINICAL_TRIALS withdrawal · 2025-07-14Clinical Trial Update: Evaluation the Safety and Efficacy of Cilostazol in Treatment of Patients With Fatty Liver Disease [Phase 1, Phase 2]
A clinical trial evaluating the safety and efficacy of Cilostazol for nonalcoholic fatty liver disease has been withdrawn, covering Phase 1 …
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Prospective Cohort and Biobank of Patients With Nonalcoholic Fatty Liver Disease
A prospective cohort and biobank study on nonalcoholic fatty liver disease and related steatohepatitis (NAFLD/MASH/NASH) is currently recrui…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Ultrasound Index Fat Fraction [NA]
A completed clinical trial evaluating ultrasound index fat fraction for detecting hepatic steatosis, sponsored by SuperSonic Imagine.
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Exploratory Analysis of Enhanced Liver Function (ELF) Test to Detect Early Fatty Liver in High Risk Population
Exploratory clinical trial evaluating the Enhanced Liver Function (ELF) test to detect early fatty liver in a high-risk population; currentl…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Accuracy of Imaging Techniques in Diagnosing Steatohepatitis and Fibrosis in NAFLD Patients [NA]
A recruiting trial evaluating the accuracy of imaging techniques for diagnosing non-alcoholic steatohepatitis and fibrosis in patients with …
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CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: Safety Study of OA-235i in Subjects With Nonalcoholic Steatohepatitis [Phase 1]
A Phase 1 safety study of OA-235i in nonalcoholic steatohepatitis and nonalcoholic fatty liver disease has completed.
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CLINICAL_TRIALS withdrawal · 2025-06-13Clinical Trial Update: Diabetes Prevention and Education [NA]
The clinical trial update indicates a University of Maryland, Baltimore-sponsored study on diabetes prevention and education has been withdr…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Effect of Bempedoic Acid on Liver Fat in Individuals With Nonalcoholic Fatty Liver Disease and Type 2 Diabetes [NA]
A clinical trial is investigating whether bempedoic acid can affect liver fat in individuals with nonalcoholic fatty liver disease and type …
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Dapagliflozin in Nonalcoholic Fatty Liver Disease (NAFLD) and Type 2 Diabetes Mellitus Patients (T2DM). [Phase 1, Phase 2]
Status update on a Phase 1/Phase 2 trial evaluating dapagliflozin in patients with type 2 diabetes mellitus and nonalcoholic fatty liver dis…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Characterization of the Microbiome in Peritoneum, Jejunum, Rectum and Stool
Clinical trial update describing microbiome characterization in the peritoneum, jejunum, rectum, and stool among participants with obesity a…
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: The Effects of Dihydromiricetin on MASLD [NA]
A clinical trial evaluating Dihydromiricetin for nonalcoholic fatty liver disease (MASLD) has completed, according to ClinicalTrials.gov, sp…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Moderately Carbohydrate-restricted Diet to Treat NAFLD in Adolescents [NA]
ClinicalTrials.gov entry notes a study evaluating a moderately carbohydrate-restricted diet to treat nonalcoholic fatty liver disease and ob…
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CLINICAL_TRIALS withdrawal · 2025-05-15Clinical Trial Update: A Phase 3 Study Evaluating the Safety and Efficacy of Denifanstat in Patients With MASH and F2/F3 Fibrosis [Phase 3]
Phase 3 study evaluating denifanstat for metabolic dysfunction-associated steatohepatitis (MASH) and fibrosis has been withdrawn.
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: The Efficacy of Pedometer-motivated Physical Activity for the Management of Patients With MASLD. [NA]
A clinical trial update indicates an ongoing, invitation-only study evaluating the impact of pedometer-motivated physical activity on MASLD …