Non-valvular Atrial Fibrillation
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: Safety and Effectiveness of Apixaban Compared to Warfarin in Patients With Non-valvular Atrial Fibrillation (a Type of Irregular Heart Rhythm) at Higher Chance of Bleeding
A completed clinical trial comparing apixaban to warfarin in patients with non-valvular atrial fibrillation who have a higher risk of bleedi…
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CLINICAL_TRIALS trial_result · 2024-05-20Clinical Trial Update: Safety and Effectiveness of Apixaban in Very Elderly Patients With Non-valvular Atrial Fibrillation (NVAF) Compared to Warfarin Using Administrative Claims Data
A Pfizer-sponsored analysis evaluates safety and effectiveness of apixaban versus warfarin in very elderly patients with non-valvular atrial…
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CLINICAL_TRIALS research · 2024-05-13Clinical Trial Update: Left Atrial Appendage Closure in Patients With Non-valvular Atrial Fibrillation and End-stage Chronic KIDNEY Disease [NA]
This ClinicalTrials.gov entry describes an ongoing study evaluating left atrial appendage closure in patients with non-valvular atrial fibri…
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: WAVECREST Post Market Clinical Follow-Up (PMCF) Study [NA]
Post-market clinical follow-up study for WAVECREST in non-valvular atrial fibrillation has terminated; results posted.
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CLINICAL_TRIALS trial_result · 2024-01-11Clinical Trial Update: Safety and Effectiveness of Apixaban Compared to Warfarin in Secondary Prevention in Patients With Atrial Fibrillation
A clinical trial comparing apixaban to warfarin for secondary prevention in non-valvular atrial fibrillation has completed; results were pos…
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CLINICAL_TRIALS trial_result · 2023-04-24Clinical Trial Update: Optimal Antithrombotic Therapy for ACS Patients Concomitant With AF and Implanted With New-generation DES (OPTIMA-3, 4) [Phase 4]
Phase 4 trial update evaluating optimal antithrombotic therapy for acute coronary syndrome patients with non-valvular atrial fibrillation wh…
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CLINICAL_TRIALS trial_result · 2022-06-24Clinical Trial Update: AMPLATZER™ Cardiac Plug Observational Post-Approval Study
Post-approval observational study of the AMPLATZER Cardiac Plug in non-valvular atrial fibrillation has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-09-02Clinical Trial Update: Impact of Anticoagulation Therapy on the Cognitive Decline and Dementia in Patients With Non-Valvular Atrial Fibrillation [Phase 4]
Phase 4 trial update assessing how anticoagulation therapy affects cognitive decline and dementia in patients with non-valvular atrial fibri…
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CLINICAL_TRIALS trial_result · 2020-11-10Clinical Trial Update: ORal anticoaGulants in diAbetic and Nondiabetic Patients With nOn-valvular Atrial fibrillatioN (ORGANON) [Phase 4]
Phase 4 clinical trial update evaluating oral anticoagulants in diabetic and non-diabetic patients with non-valvular atrial fibrillation.
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CLINICAL_TRIALS trial_result · 2019-11-04Clinical Trial Update: Safety and Effectiveness of Oral Anticoagulants in Patients With Non-valvular Atrial Fibrillation
Clinical trial update on the safety and effectiveness of oral anticoagulants in patients with non-valvular atrial fibrillation has completed…
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CLINICAL_TRIALS trial_result · 2019-08-19Clinical Trial Update: Assessment of an Education and Guidance Programme for Eliquis Adherence in Non-Valvular Atrial Fibrillation (AEGEAN) [Phase 4]
Phase 4 trial assessing an education and guidance programme to promote Eliquis (apixaban) adherence in non-valvular atrial fibrillation.
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CLINICAL_TRIALS trial_result · 2019-01-30Clinical Trial Update: A Real-World Comparison of Safety and Effectiveness of Novel Oral Anti-Coagulant (NOAC) Naïve and Warfarin Naïve Non-Valvular Atrial Fibrillation (NVAF) Patients With Medicare Advantage Coverage
A completed real-world study comparing safety and effectiveness of NOAC-naïve versus warfarin-naïve patients with non-valvular atrial fibril…
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CLINICAL_TRIALS trial_result · 2017-07-11Clinical Trial Update: A Pilot Study of Edoxaban in Patients With Non-Valvular Atrial Fibrillation and Left Atrial Appendage Closure [Phase 4]
A Phase 4 trial is evaluating edoxaban in patients with non-valvular atrial fibrillation undergoing left atrial appendage closure; the trial…
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CLINICAL_TRIALS trial_result · 2017-06-08Clinical Trial Update: The Comparative Safety and Effectiveness of Warfarin and Dabigatran Prescribed in the Non-valvular Atrial Fibrillation Population With Humana Healthcare Coverage
Clinical trial update comparing safety and effectiveness of warfarin versus dabigatran in adults with non-valvular atrial fibrillation withi…
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CLINICAL_TRIALS research · 2017-04-28Clinical Trial Update: Canadian Left Atrial Appendage Closure Study [NA]
Cardia Inc. reports a Canadian clinical trial on left atrial appendage closure for non-valvular atrial fibrillation; current status is unkno…
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CLINICAL_TRIALS trial_result · 2016-12-20Clinical Trial Update: Real Evidence of Anticoagulation Treatment in Non-valvular Atrial Fibrillation in Germany, UK and France: REACT-AF2
REACT-AF2 is a completed real-world evidence study evaluating anticoagulation treatment in non-valvular atrial fibrillation across Germany, …
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CLINICAL_TRIALS research · 2016-10-18Clinical Trial Update: Study of Safety and Efficacy of a Left Atrial Appendage Occulder [Phase 1, Phase 2]
This clinical trial update describes a study evaluating the safety and efficacy of a left atrial appendage occluder in patients with non-val…
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CLINICAL_TRIALS research · 2016-09-20Clinical Trial Update: Benefit/Risk in Real Life of New Oral Anticoagulants and Vitamin K Antagonists in Patients Aged 75 Years and Over Suffering From Non Valvular Atrial Fibrillation (nv AF)
This clinical trial evaluates the real-world benefit and risk of new oral anticoagulants and vitamin K antagonists in patients aged 75 years…
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CLINICAL_TRIALS withdrawal · 2016-08-17Clinical Trial Update: Early Post-marketing Study of Eliquis (Apixaban)
The trial update notes that an early post-marketing study of Eliquis (apixaban) for non-valvular atrial fibrillation has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-06-07Clinical Trial Update: Oral Anticoagulant Discontinuation, Adherence Patterns, Hospitalizations and Costs in Non-Valvular Atrial Fibrillation (NVAF) Patients
This clinical trial update analyzes discontinuation rates, adherence patterns, hospitalizations, and costs associated with oral anticoagulan…
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CLINICAL_TRIALS research · 2016-04-29Clinical Trial Update: Local Adaptation of Cost Effectiveness Model for Apixaban Atrial Fibrillation Indication - Venezuela
This update describes the local adaptation of a cost-effectiveness model for apixaban in non-valvular atrial fibrillation for Venezuela, wit…
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CLINICAL_TRIALS trial_result · 2016-02-17Clinical Trial Update: Comparison of Efficacy and Safety Among Dabigatran, Rivaroxaban, and Apixaban in Non-Valvular Atrial Fibrillation [Phase 4]
This Phase 4 clinical trial compares the efficacy and safety of dabigatran, rivaroxaban, and apixaban in patients with non-valvular atrial f…
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CLINICAL_TRIALS research · 2016-01-05Clinical Trial Update: The Efficacy and Safety Study of Dabigatran and Warfarin to Non-valvular Atrial Fibrillation Patients [Phase 4]
Phase 4 clinical trial update examining the efficacy and safety of dabigatran compared with warfarin in patients with non-valvular atrial fi…
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CLINICAL_TRIALS trial_result · 2015-01-26Clinical Trial Update: Safety and Pharmacokinetics Study of DU-176b Administered to Non-valvular Atrial Fibrillation With Severe Renal Impairment [Phase 3]
Phase 3 safety and pharmacokinetics study of DU-176b in non-valvular atrial fibrillation patients with severe renal impairment has been comp…
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CLINICAL_TRIALS trial_result · 2015-01-15Clinical Trial Update: Coherex WAVECREST I Left Atrial Appendage Occlusion Study
The WAVECREST I trial evaluating left atrial appendage occlusion in non-valvular atrial fibrillation has completed. The update notes the stu…