Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors [Phase 1, Phase 2]
IDEAYA Biosciences is conducting a Phase 1/2 study to evaluate the safety, pharmacokinetics, and preliminary efficacy of IDE574 in adults wi…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007) [Phase 3]
This Phase 3 clinical trial update discusses Calderasib (MK-1084) in combination with other treatments for non-small cell lung cancer (MK-10…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer [Phase 3]
This clinical trial update outlines a Phase 3 study of PF-08634404 in combination with chemotherapy for adults with locally advanced or meta…
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EMA approval · 2026-04-17EMA Authorised: Tepmetko (tepotinib hydrochloride monohydrate) — Merck Europe B.V.
The European Medicines Agency authorised Tepmetko (tepotinib hydrochloride monohydrate) for use in non-small cell lung cancer, with Merck Eu…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced Malignancies [Phase 1]
Phase 1 trial evaluating CTX-471 as a monotherapy or in combination with pembrolizumab in patients who progressed after PD-1/PD-L1 inhibitor…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: A Phase 1 Clinical Trial of AUR106 in Patients With Relapsed Advanced Malignancies [Phase 1]
Phase 1 trial of AUR106 in relapsed advanced malignancies has been terminated; the document provides a status update on this study.
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Study of Osimertinib With and Without Ramucirumab in Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 trial evaluating osimertinib with or without ramucirumab in locally advanced or metastatic non-small cell lung cancer with EGFR muta…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study of LY4175408 in Participants With Advanced Cancer [Phase 1]
A Phase 1 clinical trial evaluating LY4175408 in participants with advanced cancers, including non-small cell lung cancer, small cell lung c…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Comprehensive Prospective Comparison Of Two Robotic Platforms In Anatomical Lung Resections: Clinical Outcomes And Cost-utility Analysis
Clinical trial update comparing two robotic platforms for anatomical lung resections, including clinical outcomes and a cost-utility analysi…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study Comparing BL-B01D1 With Platinum Based Chemotherapy in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer(PANKU-Lung01) [Phase 3]
Phase 3 clinical trial comparing BL-B01D1 against platinum-based chemotherapy in locally advanced or metastatic non-small cell lung cancer; …
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019) [Phase 3]
This document reports an ongoing Phase 3 clinical trial evaluating pembrolizumab with or without Sacituzumab Tirumotecan (MK-2870) in adults…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2) [Phase 3]
A Phase 3 trial to evaluate Sevabertinib versus standard treatment in adults with advanced non-small cell lung cancer harboring HER2 mutatio…
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CLINICAL_TRIALS withdrawal · 2026-04-17Clinical Trial Update: Pembrolizumab as Neoadjuvant Therapy for Resectable Stage IA3 to IIA Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
A Phase 2 clinical trial evaluating pembrolizumab as neoadjuvant therapy for resectable Stage IA3 to IIA non-small cell lung cancer was term…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Ramucirumab Plus Pembrolizumab vs Usual Care for Treatment of Stage IV or Recurrent Non-Small Cell Lung Cancer Following Immunotherapy, Pragmatica-Lung Study [Phase 3]
A Phase 3 Pragmatica-Lung study compares ramucirumab plus pembrolizumab versus usual care for stage IV or recurrent non-small cell lung canc…
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CLINICAL_TRIALS other · 2026-04-17Clinical Trial Update: A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 study of BGB-B2033 alone or with tislelizumab, with or without bevacizumab, in adults with advanced or metastatic solid tumors. Indi…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study Comparing BL-B01D1 With Docetaxel in Patients With Unresectable Locally Advanced or Metastatic EGFR Wild-type Non-small Cell Lung Cancer(PANKU-Lung02) [Phase 3]
Phase 3 trial update comparing BL-B01D1 to Docetaxel in unresectable locally advanced or metastatic EGFR wild-type non-small cell lung cance…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: KEYMAKER-U01 Umbrella Master Study: Studies of Investigational Agents With Either Pembrolizumab (MK-3475) Alone or With Pembrolizumab PLUS Chemotherapy in Participants With Non-small Cell Lung Cancer (NSCLC) (MK-3475-U01/KEYMAKER-U01)
Clinical trial update for the KEYMAKER-U01 umbrella study evaluating pembrolizumab alone or with chemotherapy in non-small cell lung cancer,…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study of Ivonescimab, Chemotherapy, and Stereotactic Radiosurgery for People With Non-Small Cell Lung Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Ivonescimab with chemotherapy and stereotactic radiosurgery for non-small cell lung cancer is currentl…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial [Phase 3]
Phase 3 trial evaluating atezolizumab after surgery to prevent recurrence in patients with early-stage non-small cell lung cancer (AASI-NSCL…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study of PHN-012 in Patients With Advanced Solid Tumors [Phase 1]
PHN-012 is being studied in a Phase 1 trial for patients with advanced solid tumors and is currently recruiting. The listed conditions inclu…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Pathophysiological Mechanisms Involved in the Pronostic and Evolution of Non-Small Cell Lung Cancer (NSCLC) at All Stages of the Disease
This clinical trial update investigates pathophysiological mechanisms involved in prognosis and progression of non-small cell lung cancer ac…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord [Phase 2]
This is a Phase 2 clinical trial update evaluating the combination of thermal ablation and spine stereotactic radiosurgery for spine metasta…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Pembrolizumab in Preventing Lung Cancer in Patients With Stage I-II Non-Small Cell Lung Cancer or High-Risk Pulmonary Nodules, the IMPRINT-Lung Study [Phase 2]
Phase 2 trial assessing pembrolizumab for prevention of lung cancer in patients with Stage I-II non-small cell lung cancer or high-risk pulm…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Sacituzumab Tirumotecan (MK-2870) as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors (MK-2870-008) [Phase 1]
Phase 1 trial MK-2870-008 evaluating sacituzumab govitecan as a single agent and in combination with pembrolizumab for advanced solid tumors…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer [Phase 3]
Clinical trial update for JoLT-Ca comparing Sublobar Resection versus Stereotactic Ablative Radiotherapy in non-small cell lung cancer; the …