Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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EMA approval · 2026-01-16EMA Authorised: Alimta (pemetrexed) — Eli Lilly Nederland B.V.
EMA has authorised the marketing of Alimta (pemetrexed) for malignant mesothelioma and non-small cell lung cancer in the EU. The marketing a…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Analysis of PD-L1, TMB, MSI and ctDNA Dynamics to Predict and Monitor Response to Immunotherapy in Metastatic Cancer.
A clinical trial is evaluating biomarkers PD-L1, tumor mutational burden, MSI, and ctDNA to predict and monitor response to immunotherapy in…
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: A Study of Roginolisib (IOA-244) in Combination With Dostarlimab With or Without Docetaxel in Metastatic Non Small-cell Lung Cancer (NSCLC) Patients [Phase 1, Phase 2]
This is a clinical trial update describing a Phase 1/2 study of Roginolisib (IOA-244) in combination with Dostarlimab, with or without Docet…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Trametinib and Pembrolizumab in Treating Patients With Recurrent Non-small Cell Lung Cancer That Is Metastatic, Unresectable, or Locally Advanced [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of trametinib and pembrolizumab in patients with recurrent or advanced non-small cell …
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: Lidocaine Decreases Postoperative Lung Cancer Reoccurance and Metatasis Risk [NA]
A clinical trial update indicates lidocaine may reduce postoperative recurrence and metastasis risk in non-small cell lung cancer, though th…
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EMA approval · 2026-01-15EMA Authorised: Pemetrexed Pfizer (previously Pemetrexed Hospira) (pemetrexed disodium;pemetrexed disodium hemipentahydrate) — Pfizer Europe MA EEIG
The European Medicines Agency authorised a pemetrexed disodium product marketed as Pemetrexed Pfizer (formerly Pemetrexed Hospira) for non-s…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Sacituzumab Tirumotecan Plus Third-Generation TKI With/Without Radiotherapy for EGFR-Mutant NSCLC Brain Metastases [Phase 2]
Phase 2 clinical trial update exploring Sacituzumab Tirumotecan with or without radiotherapy for EGFR-mutant non-small cell lung cancer with…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: A Study of DM005 in Patients With Advanced Solid Tumors [Phase 1]
DM005 is being studied in a Phase 1 trial for patients with advanced solid tumors, including non-small-cell lung cancer and head and neck sq…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Nelmastobart in Combination With Docetaxel in Non Small Cell Lung Cancer [Phase 2]
This clinical trial update notes a Phase 2 study of Nelmastobart in combination with docetaxel for non-small cell lung cancer, currently rec…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: SL-28 for Advanced Solid Tumours [Phase 1, Phase 2]
Clinical trial update for SL-28 in advanced solid tumours across multiple indications; the Phase 1/Phase 2 study is currently not yet recrui…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: A Study Evaluating Neoadjuvant Chemotherapy, Concurrent Chemoradiotherapy Combined With Dual Immune Checkpoint Blockade in Patients With Locally Advanced Non-Small Cell Lung Cancer [Phase 2]
Phase 2 study evaluating neoadjuvant chemotherapy with concurrent chemoradiotherapy plus dual immune checkpoint blockade in locally advanced…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Radiation During Osimertinib Treatment: a Safety and Efficacy Cohort Study [Phase 2]
A Phase 2 cohort study evaluating the safety and efficacy of radiation therapy given during Osimertinib treatment in patients with EGFR-posi…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: First-in-Human Expanded Cohort Study of Intrapleural Administration of TolueneSulfonamide in Patients With Malignant Pleural Effusion [Phase 1, Phase 2]
This early-phase study investigates intrapleural administration of toluene sulfonamide in patients with malignant pleural effusions, includi…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Safety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung Cancer [Phase 1]
A Phase 1 clinical trial exploring safety of combining antimicrobial therapy with precision radiation therapy for oligoprogressive, early-st…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Amivantamab With Tyrosine Kinase Inhibitors (TKI) for Advanced NSCLC With ALK, ROS1, or RET Alterations [Phase 1, Phase 2]
This update covers an ongoing Phase 1/2 study of amivantamab combined with tyrosine kinase inhibitors for advanced non-small cell lung cance…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Intratumoral N17350 in Advanced Solid Tumors [Phase 1, Phase 2]
Update on the investigational intratumoral therapy N17350 being studied in advanced solid tumors in Phase 1 and Phase 2 trials, sponsored by…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors [Phase 2]
ClinicalTrials.gov update for QUILT-3.055, a Phase 2 study of combination immunotherapies in patients who previously received immune checkpo…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Mobilization Before and After Video-Assisted Thoracoscopic Surgery Lobectomy/Segmentectomy
A completed clinical trial update examining mobilization before and after video-assisted thoracoscopic surgery lobectomy or segmentectomy fo…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: A Study of LY4170156 in Participants With Selected Advanced Solid Tumors [Phase 1]
An early-phase study evaluating LY4170156 in selected advanced solid tumors is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Glecirasib Combined With Ivonescimab for First-line Treatment of KRAS G12C-mutated NSCLC [Phase 1, Phase 2]
Clinical trial update indicates a first-line study of Glecirasib plus Ivonescimab for KRAS G12C-mutated non-small cell lung cancer, currentl…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: PET/CT Changes During Chemoimmunotherapy and Radiation Therapy in Patients With Stage IV Non-small Cell Lung Cancer [NA]
This clinical trial is investigating PET/CT imaging changes during chemoimmunotherapy and radiation therapy for stage IV non-small cell lung…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Nivolumab Plus Ramucirumab in Patients With Recurrent, Advanced, Metastatic NSCLC [Phase 2]
This clinical trial update reports on a Phase 2 study of the combination of nivolumab and ramucirumab in patients with recurrent, advanced, …
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: A Study to Evaluate Chemotherapy Plus Osimertinib Against Chemotherapy Plus Placebo in Patients With Non-small Cell Lung Cancer (NSCLC) [Phase 3]
A Phase 3 trial evaluates adding osimertinib to chemotherapy versus chemotherapy with placebo in non-small cell lung cancer, with results po…
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: Impact of Pretreatment Emotional Distress on Survival and the Predictive Role of Peripheral Biomarkers in Immunotherapy Response Among Gastroesophageal and Lung Cancer Patients
A completed clinical trial investigates whether pretreatment emotional distress affects survival in patients receiving immunotherapy. It als…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: A Prospective Multicenter Study of the Association Between TCM Syndromes and EGFR-TKI Efficacy in Lung Cancer Patients
This prospective multicenter study investigates whether traditional Chinese medicine syndrome patterns influence the efficacy of EGFR-TKI th…