Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer [Phase 2]
Phase 2 clinical trial evaluating autologous T cells engineered to express T-cell receptors against neoantigens in metastatic cancer, curren…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC) [Phase 1, Phase 2]
This clinical trial update describes the AZA-AEGEAN regimen—neoadjuvant inhaled azacitidine with platinum-based chemotherapy and durvalumab—…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial) [NA]
An update on the ALCHEMIST Screening Trial, a National Cancer Institute study evaluating genetic testing in screening patients with operable…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Serplulimab Combined With Chemotherapy in Patients With Resectable Non-small-cell Lung Cancer [Phase 2]
A Phase 2 trial update evaluating serplulimab in combination with chemotherapy as neoadjuvant therapy for resectable non-small-cell lung can…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies [Phase 2]
Phase 2 clinical trial evaluating a PD-1–blocking monoclonal antibody in combination with a metabolic modulator for several solid tumors is …
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Relatrilfa-α Plus Single-Agent Chemotherapy as Neoadjuvant Therapy for Resectable Stage II-III NSCLC (Phase 2) [Phase 2]
Phase 2 clinical trial evaluating Relatrilfa-α in combination with single-agent chemotherapy as neoadjuvant therapy for resectable stage II-…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009) [Phase 3]
A Phase 3 trial comparing Sacituzumab Tirumotecan versus pemetrexed plus carboplatin in EGFR-mutated, advanced nonsquamous non-small cell lu…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Sleeve Lobectomy for Lung Cancer in Minimally Invasive Surgical Techniques
A clinical trial is evaluating sleeve lobectomy for lung cancer using minimally invasive surgical techniques and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: POTENT - Tepotinib in Combination With Pembrolizumab in NSCLC [Phase 1]
This document reports an ongoing Phase 1 trial evaluating the combination of tepotinib and pembrolizumab for non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers [Phase 1]
A Phase I trial evaluating [177Lu]Lu-NNS309, a radiopharmaceutical, in multiple advanced cancers including pancreatic ductal adenocarcinoma,…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Nivolumab After Surgery and Chemotherapy in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer (An ALCHEMIST Treatment Trial) [Phase 3]
Nivolumab is being studied after surgery and chemotherapy in stage IB to IIIA non-small cell lung cancer as part of the ALCHEMIST Treatment …
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J) [Phase 2]
A Phase 2 clinical trial is evaluating pembrolizumab in combination with MK-1084 in KRAS G12C-mutant non-small cell lung cancer. The study i…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial evaluating a cancer lysate vaccine with Montanide ISA-51 VG, with or without the IL-15 super-agonist N-80…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202) [Phase 3]
A Phase 3 randomized trial (CodeBreaK 202) comparing a sotorasib-platinum doublet to a pembrolizumab-platinum doublet as first-line therapy …
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Zorifertinib Plus Intra-Ommaya CSF Chemotherapy for Leptomeningeal Progression in NSCLC After Third-Generation EGFR-TKI [Phase 2]
Phase 2 trial investigating Zorifertinib with intra-Ommaya CSF chemotherapy for leptomeningeal progression in non-small cell lung cancer aft…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Sutetinib Maleate Capsule in Locally Advanced or Metastatic NSCLC [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of Sutetinib Maleate Capsule in locally advanced or metastatic non-small cell lung…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating BH-30643 in subjects with locally advanced or metastatic non-small cell lung cancer harboring EGFR and…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial [Phase 3]
A Phase 3 clinical trial (ACHIEVE) is evaluating chemotherapy plus immunotherapy versus immunotherapy alone in older adults with stage IIIB-…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Aurora Kinase Inhibitor LY3295668 in Combination With Osimertinib for the Treatment of Advanced or Metastatic EGFR-Mutant Non-squamous Non-small Cell Lung Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating LY3295668 in combination with osimertinib for advanced or metastatic EGFR-mutant non-squamous non-smal…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC [Phase 3]
Phase 3 global trial assessing durvalumab plus domvanalimab after concurrent chemoradiation in stage III unresectable non-small cell lung ca…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Phase II Study of Sacituzumab Tirumotecan in Combination With Furmonertinib in Patients With Non-squamous Non-Small Cell Lung Cancer Who Have Progressed After EGFR-TKI and Platinum-Based Chemotherapy [Phase 2]
Phase II trial evaluating sacituzumab tirumotecan in combination with furmonertinib for non-squamous non-small cell lung cancer that progres…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A First-in-Human Study of CKD-703 in Advanced Solid Tumors and Non-Small Cell Lung Cancer [Phase 1, Phase 2]
A first-in-human study of CKD-703 in advanced solid tumors and non-small cell lung cancer is currently recruiting in Phase 1/Phase 2.
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating the combination of zimberelimab and domvanalimab for non-small cell lung cancer is currently active but no…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Efficacy and Safety Evaluation of PLB1004 in Patients With Non-squamous NSCLC Harboring EGFR Exon 20 Insertion. [Phase 3]
A Phase 3 clinical trial evaluating the efficacy and safety of PLB1004 in non-squamous non-small cell lung cancer with EGFR exon 20 insertio…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Lay Navigation Intervention for Patients With Lung Cancer [NA]
This clinical trial update describes a lay navigation intervention intended to support patients with lung cancer, including non-small cell a…