Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Immune Response to Immunotherapy in Lung Cancer: Study of Sputum and Blood Samples [NA]
This clinical trial update describes a study at University Hospital Tours examining immune responses to immunotherapy in non-small cell lung…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: A Phase I/IIa Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AZD0022 as Monotherapy and in Combination With Anti-cancer Agents in Adult Participants With Tumours Harbouring a KRASG12D Mutation [Phase 1]
AstraZeneca's Phase I/IIa study of AZD0022 in KRASG12D-mutant tumors has been terminated. The study enrolled adults with advanced solid tumo…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain Metastases [Phase 2]
Phase 2 trial evaluating osimertinib with or without bevacizumab in EGFR-positive non-small cell lung cancer with brain metastases; results …
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Global Study of Volrustomig (MEDI5752) Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy for Participants With Metastatic Non-small Cell Lung Cancer. [Phase 3]
Global Phase 3 trial comparing Volrustomig plus chemotherapy versus pembrolizumab plus chemotherapy in metastatic non-small cell lung cancer…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: A Vaccine (CIMAvax-EGF) for the Prevention of Lung Cancer Development or Recurrence [EARLY_Phase 1]
An early-phase Phase 1 trial of CIMAvax-EGF for prevention of lung cancer development or recurrence has completed.
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Survey of Brigatinib Used To Treat People With Non-Small Cell Lung Cancer
Takeda-sponsored clinical trial evaluating brigatinib for non-small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Multi-center, Non-interventional, Prospective Study of Durvalumab in Unresectable Locally Advanced NSCLC in Routine Clinical Practice in Russia
A multi-center, non-interventional prospective study evaluating durvalumab in unresectable locally advanced non-small cell lung cancer in ro…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Correlation Between Tissue and Plasmatic EGFR in CBNPC With EGFR Mutation or Predictive Factor of EGFR Mutation [NA]
The clinical trial update evaluates the correlation between tissue and plasma EGFR status in non-small cell lung cancer with EGFR mutation o…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
A clinical trial is evaluating benefits and harms of cannabis/cannabinoid use among cancer patients treated in community oncology clinics; r…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Integrated Genomics in Oncogene-driven NSCLC With Acquired Resistance
A clinical trial update on an integrated genomics approach in oncogene-driven non-small cell lung cancer with acquired resistance, currently…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Study of Novel Treatment Combinations in Patients With Lung Cancer [Phase 2]
A Phase 2 clinical trial sponsored by Gilead Sciences is evaluating novel treatment combinations in patients with non-small cell lung cancer…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Brentuximab Vedotin With Pembrolizumab in Metastatic Solid Tumors [Phase 2]
Phase 2 trial of brentuximab vedotin in combination with pembrolizumab for metastatic solid tumors has completed, enrolling patients with me…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Limertinib Plus Carboplatin and Etoposide for EGFR-mutant NSCLC With SCLC Transformation After EGFR-TKI Progression [Phase 2]
Phase 2 clinical trial evaluating limertinib in combination with carboplatin and etoposide for EGFR-mutant non-small cell lung cancer with t…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: A Study to Evaluate the Benefit of Adding Durvalumab After Chemotherapy, Durvalumab and Surgery in Patients With Early-stage, Operable, Non-small Cell Lung Cancer. [Phase 3]
A Phase 3 trial evaluating adding Durvalumab after chemotherapy and in combination with surgery for early-stage operable non-small cell lung…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Phase II Neoadjuvant Study of Garsorasib Followed by Ivonescimab Plus Chemotherapy in Resectable Stage IIA-IIIB KRAS G12C-Mutant NSCLC (GIVEN Study) [Phase 2]
Phase II neoadjuvant trial exploring Garsorasib followed by Ivonescimab plus chemotherapy in resectable stage IIA-IIIB KRAS G12C-mutant non-…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Experiences w/ & Attitudes Towards Immune Chckpt Inhibitors in NSCLC Patients Single Center Survey Based Study
This document describes a single-center survey of NSCLC patients assessing experiences with and attitudes toward immune checkpoint inhibitor…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Feasibility Study to Investigate Rectal Mucus in Aero-Digestive Tract Cancer.
A feasibility study sponsored by Origin Sciences is recruiting to investigate rectal mucus in aero-digestive tract cancers, including Non-Sm…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A) [Phase 1, Phase 2]
Clinical trial update for MK-3475-01A/KEYMAKER-U01A evaluating pembrolizumab with or without chemotherapy in treatment-naïve Stage IV non-sm…
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CLINICAL_TRIALS withdrawal · 2026-03-16Clinical Trial Update: Managed Access Programs for INC280, Capmatinib
The document reports that the managed access program for capmatinib (INC280) is no longer available.
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Durvalumab and Tremelimumab in Combination With Chemotherapy in HIV-infected Patients With Non-small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating durvalumab plus tremelimumab in combination with chemotherapy for HIV-infected patients with non-small cel…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: SYS6090 Combination Therapy in Advanced Lung Cancer [Phase 1, Phase 2]
Clinical trial update for SYS6090 combination therapy in advanced lung cancer, covering Phase 1 and Phase 2 studies; currently not yet recru…
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CLINICAL_TRIALS other · 2026-03-16Clinical Trial Update: Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations [Phase 3]
A Phase III open-label trial is evaluating first-line Dato-DXd in combination with Rilvegostomig for advanced non-squamous non-small cell lu…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Study of ONO-7475 in Combination With Osimertinib in EGFR Gene Mutation-positive Non-small Cell Lung Cancer [Phase 1]
A Phase 1 study evaluating ONO-7475 in combination with osimertinib for EGFR mutation-positive non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Study of the Expression of Met Receptor Fragments in Non Small Cell Lung Cancers [NA]
This entry notes the completion of a clinical trial studying the expression of Met receptor fragments in non-small cell lung cancer.
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene) [Phase 1]
Phase 1 study Beamion LUNG-1 evaluating multiple doses of Zongertinib in adults with advanced cancers harboring HER2 gene alterations, inclu…