Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Trial Comparing Systemic Therapy Alone and With Local Ablative Treatment for Stage IV NSCL Cancer Patients [NA]
A clinical trial evaluating whether adding local ablative treatment to systemic therapy improves outcomes for patients with stage IV non-sma…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours [Phase 1]
Clinical trial update describes a Phase 1 dose-escalation study of [225Ac]-FPI-2068 in adults with advanced solid tumors, currently recruiti…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Collaborative Clinical-translational Cohort of Amivantamab Plus Lazertinib and Amivantamab Plus Chemotherapy in Patients With EGFR-mutant, Locally Advanced or Metastatic/Recurrent Non-Small Cell Lung Cancer (INSTAR Study) [Phase 2]
Phase 2 clinical trial entry (INSTAR) evaluating amivantamab in combination with lazertinib or with chemotherapy in EGFR-mutant locally adva…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Singing Training vs Usual Care 6-18 Months After Surgical Resection for Non-small Cell Lung Cancer (NSCLC) [NA]
A clinical trial comparing singing training to usual care 6-18 months after surgical resection for non-small cell lung cancer. It is current…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Immunonutrition Reduces Acute Esophagitis After Thoracic Radiotherapy in Lung Cancer [Phase 3]
A Phase 3 clinical trial is assessing whether immunonutrition can reduce acute esophagitis in patients with lung cancer undergoing thoracic …
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors [Phase 1, Phase 2]
Clinical trial update for VT3989 in adults with metastatic solid tumors, including mesothelioma and non-small cell lung cancer, currently re…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023] [Phase 3]
A Phase 3 clinical trial evaluating pembrolizumab with or without maintenance Sac-TMT (MK-2870) in metastatic squamous non-small cell lung c…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: A Study of TAS3351 in NSCLC Patients With EGFRmt [Phase 1]
Phase 1 study of TAS3351 in EGFR-mutant non-small cell lung cancer was terminated, with results posted on 2026-04-02.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Study of Safety and Efficacy of Ceritinib in Combination With Nivolumab in Patients With ALK-positive Non-small Cell Lung Cancer [Phase 1]
Phase 1 study evaluating safety and potential efficacy of combining ceritinib with nivolumab in patients with ALK-positive non-small cell lu…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: A Study to Investigate Safety, Tolerability, PK and Anti-tumor Activity of TRX-221 in EGFRm NSCLC Patients [Phase 1, Phase 2]
A Phase 1/2 trial of TRX-221 in EGFR-mutant non-small cell lung cancer has been terminated; the update covers safety, tolerability, pharmaco…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Roll-over Study to Allow Access to Certinib (LDK378) for Patients Who Are on Ceritinib Treatment in a Novartis-sponsored Study [Phase 4]
This is a rollover/compassionate-use style update allowing patients already on ceritinib to continue receiving the drug within a Novartis-sp…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Stereotactic Body Radiation Therapy Followed by Surgery in Treating Patients With Stage I-IIIA Non-small Cell Lung Cancer [EARLY_Phase 1]
This EARLY Phase 1 clinical trial evaluates stereotactic body radiation therapy followed by surgery for patients with stage I to IIIA non-sm…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Study to Investigate Petosemtamab in Adults With Metastatic Non-Small Cell Lung Cancer [Phase 2]
This is a Phase 2 clinical trial evaluating petosemtamab in adults with metastatic non-small cell lung cancer, including squamous and non-sq…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease [Phase 1]
Phase 1 study evaluating intravenous and intrathecal nivolumab for leptomeningeal disease in melanoma and non-small cell lung cancer patient…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Qualitative Study on Detection & Tx of NSCLC in Pts w/ a History of Alcohol or SUD
An ongoing qualitative study sponsored by the University of Southern California is investigating detection and treatment of non-small cell l…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Pulsatile High-dose Furmonertinib in EGFR-mutant NSCLC With Leptomeningeal Metastasis [NA]
A clinical trial is evaluating pulsatile high-dose furmonertinib for EGFR-mutant non-small cell lung cancer with leptomeningeal metastasis; …
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Cadherin 3(CDH3)-Targeted PET in Lung Malignant Tumors
A recruiting clinical trial at Peking University People's Hospital is evaluating a cadherin-3 (CDH3) targeted PET imaging agent for lung mal…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Prospective Trial Assessing Real World Outcomes Response to Pembro in Black Patients w/ NSCLC [Phase 2]
Prospective Phase 2 trial assessing real-world outcomes of pembrolizumab in Black patients with non-small cell lung cancer; currently recrui…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Multimodality Treatment in Stage III Non-small Cell Lung Cancer (NSCLC) [Phase 2]
This clinical trial update describes a Phase 2 multimodality treatment study for stage III non-small cell lung cancer, currently active but …
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Pharmacokinetic Similarity Between ABP 234 and Keytruda® (Pembrolizumab) [Phase 3]
This Phase 3 clinical trial update reports pharmacokinetic similarity between ABP-234, a pembrolizumab biosimilar, and Keytruda (pembrolizum…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Neoadjuvant Therapy With Ensartinib Combined With Chemotherapy for ALK-positive Non - Small Cell Lung Cancer (NSCLC) [Phase 1, Phase 2]
A Phase 1/Phase 2 neoadjuvant trial testing ensartinib in combination with chemotherapy for ALK-positive non-small cell lung cancer, current…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Genomically Guided Radiation Dose Personalization in Locally Advanced NSCLC [EARLY_Phase 1]
Early-phase trial results explore genomically guided radiation dose personalization for locally advanced non-small cell lung cancer, aiming …
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A Study to Learn About the Study Medicine Called PF-08046032 in People With Advanced Cancers [Phase 1]
Phase 1 clinical trial update for PF-08046032 in people with advanced cancers; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: FAP-targeted PET/NIR in Lung Malignant Tumors
An ongoing clinical trial is evaluating a fibroblast activation protein (FAP)-targeted PET/near-infrared imaging agent in non-small cell lun…
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CLINICAL_TRIALS other · 2026-04-01Clinical Trial Update: Managed Access Programs for LDK378, Ceritinib
This update notes that the managed access program for ceritinib (LDK378) is no longer available; sponsor is Novartis Pharmaceuticals, and el…