Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: GEN1047 for Solid Tumors - First in Human (FIH) Trial [Phase 1, Phase 2]
Genmab's GEN1047 first-in-human Phase 1/2 trial in solid tumors has been terminated, with indications including breast cancer, endometrial c…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: An Observational Study to Evaluate the Real-World Clinical Management and Outcomes of ALK-Positive Advanced NSCLC Participants Treated With Alectinib
This clinical trial update describes an observational real-world study of ALK-positive advanced non-small cell lung cancer patients treated …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Addition of the Pill Chemotherapy, Cabozantinib, to the Standard Immune Therapy Nivolumab Compared to Standard Chemotherapy for Non-small Cell Lung Cancer [Phase 2]
This clinical trial update describes a Phase 2 study evaluating adding cabozantinib to nivolumab versus standard chemotherapy for non-small …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer [Phase 3]
A Phase 3 clinical trial is evaluating adding an antibody to standard chemoradiation, followed by one year of antibody therapy, for patients…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 study of LY4101174 in participants with recurrent, advanced or metastatic solid tumors is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Study of Combination Therapy With Amivantamab and Docetaxel in Participants With Metastatic Non-small Cell Lung Cancer [Phase 1, Phase 2]
This clinical trial update outlines a Phase 1/Phase 2 study evaluating the combination of amivantamab and docetaxel in participants with met…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of TT125-802 in Subjects With Advanced Solid Tumors [Phase 1]
A Phase 1 clinical trial update evaluating TT125-802 in adults with advanced solid tumors, focusing on safety, tolerability, pharmacokinetic…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Osimertinib and Necitumumab in Treating Patients With EGFR-Mutant Stage IV or Recurrent Non-small Cell Lung Cancer Who Have Progressed on a Previous EGFR Tyrosine Kinase Inhibitor [Phase 1]
A Phase 1 clinical trial update evaluating the combination of osimertinib and necitumumab in EGFR-mutant stage IV or recurrent non-small cel…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer [Phase 1]
This Clinical Trial Update describes a Phase 1 study evaluating the addition of BAY 1895344 to standard chemotherapy (cisplatin or cisplatin…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Thoracic Radiotherapy and Inhibition of PD-1 and LAG-3 for Locally Advanced Non-Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating the combination of thoracic radiotherapy with PD-1 and LAG-3 inhibitors for locally advanced non-small cel…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Risk of Chemotherapy Toxicity in Older Patients With Blood Cancer or Non-small Cell Lung Cancer
This clinical trial update discusses the risk of chemotherapy toxicity in older patients with hematologic malignancies or non-small cell lun…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial update evaluating amivantamab in participants with advanced or metastatic solid tumors, including epidermal growth fa…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies [Phase 1, Phase 2]
Ongoing Phase 1/2 clinical trial evaluating BMS-986523 alone and in combination with anti-cancer agents in advanced solid malignancies, incl…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer [Phase 3]
A Phase 3 trial evaluating Divarasib plus Pembrolizumab versus Pembrolizumab with pemetrexed and platinum in previously untreated KRAS G12C-…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Addition of the Drug Atezolizumab to the Usual Radiation Treatment for Patients With Early Non-small Cell Lung Cancer [Phase 3]
A Phase 3 clinical trial is evaluating adding atezolizumab to standard radiation therapy for patients with early-stage non-small cell lung c…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss [Phase 1, Phase 2]
The document provides an update on a Phase 1/2 clinical trial assessing the safety and tolerability of TNG456 alone and with abemaciclib in …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Pulmonary Rehabilitation in Advanced Lung Cancer Survivors [Phase 2]
A Phase 2 clinical trial evaluating pulmonary rehabilitation in advanced non-small cell lung cancer survivors is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)
A completed Travera Inc trial evaluating TraveraRTGx and a tumor-cell biomarker intended to guide rapid therapy decisions across multiple ca…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors [Phase 1]
Plexium, Inc. is conducting a first-in-human Phase 1 study of PLX-61639 in locally advanced or metastatic solid tumors, and the trial is cur…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of JNJ-86974680 in Participants With Advanced Non-small Cell Lung Cancer [Phase 1]
A Phase 1 study evaluating JNJ-86974680 in participants with advanced non-small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: INTENSE: A Phase I/II Study of INhomogeneous Targeted Dose Escalation in Non-Small CEll Lung Cancer [Phase 1, Phase 2]
INTENSE is a Phase I/II study of inhomogeneous targeted dose escalation in non-small cell lung cancer. The trial has been terminated.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Anvumetostat Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion (Master Protocol) (MTAPESTRY 104). [Phase 1]
A Phase 1 master protocol trial (MTAPESTRY 104) is evaluating Anvumetostat, alone or with other therapies, in patients with advanced thoraci…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004) [Phase 3]
A Phase 3 clinical trial evaluating Calderasib (MK-1084) in combination with Pembrolizumab (MK-3475) for KRAS G12C mutant non-small cell lun…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Addition of AZD6738 (Ceralasertib) to Immunotherapy to Increase Time Without Cancer for Patients With Non-Small Cell Lung Cancer [Phase 3]
Phase 3 trial evaluating AZD6738 (ceralasertib) in combination with immunotherapy for Non-Small Cell Lung Cancer; the study is currently ACT…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones [Phase 1]
Phase 1 safety study of Sn-117m-DTPA for cancers that have spread to bone, including metastatic breast, lung, and prostate cancers; the tria…