Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Study of XB010 in Subjects With Solid Tumors [Phase 1]
A Phase 1 trial evaluating XB010 in locally advanced or metastatic solid tumors is currently recruiting across multiple indications.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202) [Phase 3]
Phase 3 clinical trial comparing Pumitamig to Pembrolizumab in previously untreated advanced non-small cell lung cancer with PD-L1 ≥ 50%; cu…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 clinical trial update for Enzelkitug as a single agent and in combination with a checkpoint inhibitor in adults with locally advance…
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CLINICAL_TRIALS other · 2026-04-15Clinical Trial Update: A Study to Evaluate Two Dosing Regimens of Subcutaneous Nivolumab in Combination With Intravenous Ipilimumab and Chemotherapy in Participants With Previously Untreated Metastatic or Recurrent Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 trial evaluating two dosing regimens of subcutaneous nivolumab in combination with intravenous ipilimumab and chemotherapy in previo…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Anamorelin Hydrochloride in Reducing Anorexia in Patients With Advanced Non-small Cell Lung Cancer [Phase 2, Phase 3]
This document reports an ongoing phase 2/3 clinical trial evaluating anamorelin hydrochloride to reduce anorexia in patients with advanced n…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Phase Ib Study to Evaluate the Safety and Preliminary Efficacy of IL6-receptor Antibody Sarilumab in Combination With antiPD1 Antibody Cemiplimab for Patients With Non-small Cell Lung Cancer. [Phase 1]
Phase Ib/Phase 1 trial evaluating the safety and preliminary efficacy of the IL-6 receptor antibody sarilumab in combination with the anti-P…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial [Phase 2]
Phase 2 clinical trial update on IMMUNO-BIOMAP evaluating biomarkers to predict response to first-line PD-1/PD-L1 immunotherapy and to guide…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Zelenectide Pevedotin in NECTIN4 Amplified Advanced or Metastatic Non-small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial update for Zelenectide Pevedotin in NECTIN4-amplified advanced or metastatic non-small cell lung cancer; the study is…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors. [Phase 1]
A Phase 1 trial evaluating escalating doses of the investigational agent BMS-986463 to assess safety, tolerability, and early signals of act…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors [Phase 1]
This ClinicalTrials.gov entry describes a Phase 1 study to determine a suitable dose of ASP5834 in adults with solid tumors, including non-s…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Prospective Observational Study of Changes in Cortisol Levels After Neoadjuvant Immunotherapy and Their Prognostic Value in Patients With NSCLC
This clinical trial update describes an observational study examining changes in cortisol levels after neoadjuvant immunotherapy in non-smal…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Dyadic Yoga Intervention in Improving Physical Performance and Quality of Life in Patients With Stage I-IV Non-small Cell Lung or Esophageal Cancer Undergoing Radiotherapy and Their Caregivers [NA]
This clinical trial update describes a dyadic yoga intervention study to improve physical performance and quality of life in patients with s…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Met Non Small Cell Cancer Registry (MOMENT)
The MOMENT registry, sponsored by EMD Serono Research & Development Institute, collects data on MET-related non-small cell cancer and is cur…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Incentive Spirometry to Improve Outcomes in Lung Cancer Patients Undergoing Concurrent Chemotherapy and Radiation Therapy [NA]
Clinical trial update indicates recruitment is ongoing for a study assessing incentive spirometry to improve outcomes in lung cancer patient…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: A Multinational, Randomized, Open-Label Study of Custirsen In Patients With Advanced or Metastatic (Stage IV) Non-Small Cell Lung Cancer [Phase 3]
This update notes the completion of a Phase 3 multinational, randomized, open-label study evaluating custirsen in patients with advanced or …
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CLINICAL_TRIALS other · 2026-04-15Clinical Trial Update: ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers [Phase 1, Phase 2]
This clinical trial update reports on a Phase 1/Phase 2 study of ADI-PEG 20 in combination with gemcitabine and docetaxel for patients with …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Study of NT-175 in Adult Subjects With Unresectable, Advanced, and/or Metastatic Solid Tumors That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation [Phase 1]
NT-175 is being studied in a Phase 1 trial enrolling adults with unresectable, advanced, or metastatic solid tumors positive for HLA-A*02:01…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Study of Tislelizumab in Combination With Investigational Agents in Participants With Non-Small Cell Lung Cancer [Phase 2]
Update on a Phase 2 study of tislelizumab in combination with investigational agents for non-small cell lung cancer; the trial is currently …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Online Psychosocial Intervention in Improving Social Well-Being and Support in Women With Stage I-IV Non-small Cell Lung Cancer Undergoing Treatment [NA]
This clinical trial update describes an online psychosocial intervention intended to improve social well-being and support for women with st…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Post-Market Registry of Transbronchial Cryo-assisted RFA During Routine Standard Bronchoscopic Tumor Stagng and Resection [NA]
A post-market registry study evaluating transbronchial cryo-assisted radiofrequency ablation during routine bronchoscopic tumor staging and …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer [Phase 2, Phase 3]
This update describes an ongoing Phase 2/Phase 3 clinical trial evaluating BNT327 in combination with chemotherapy and other investigational…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Reduced-dose Carboplatin-doublet-chemotherapy + Cemiplimab vs Cemiplimab Monotherapy in Treatment Naive Older and Frail Patients With Metastatic NSCLC With PD-L1 <50% [Phase 2]
Phase 2 trial evaluating reduced-dose carboplatin-doublet chemotherapy plus cemiplimab versus cemiplimab alone in treatment-naive older and …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors [Phase 1]
This is a Phase 1 trial evaluating BGB-43395 alone or in combination for advanced breast cancer and other solid tumors. Recruitment is ongoi…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Study Investigating BG-60366 in Adults With Epidermal Growth Factor Receptor (EGFR)-Mutant Non-Small Cell Lung Cancer [Phase 1]
BeOne Medicines reports a Phase 1 trial of BG-60366 in adults with EGFR-mutant non-small cell lung cancer. The study is currently active but…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Ablative STEreotactic RadiOtherapy wIth Durvalumab (MEDI4736) [Phase 2]
A Phase 2 trial evaluating ablative stereotactic radiotherapy combined with durvalumab (MEDI4736) in Stage I non-small cell lung cancer has …