Non-muscle Invasive Bladder Cancer
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: A Study of Intravesical Enfortumab Vedotin For Treatment of Patients With Non-muscle Invasive Bladder Cancer (NMIBC) [Phase 1]
A Phase 1 trial of intravesical Enfortumab Vedotin for non-muscle invasive bladder cancer was terminated, with the study status updated acco…
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Outcomes of High-risk Non-muscle Invasive Bladder Cancer Treated With Blue Light Resection [Phase 3]
A Phase 3 clinical trial evaluating blue light resection for high-risk non-muscle invasive bladder cancer is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: CISTO: Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer
Results from the CISTO trial compare intravesical therapy with surgical options as treatments for bladder cancer. The study includes non-mus…
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CLINICAL_TRIALS trial_result · 2025-10-31Clinical Trial Update: Increasing Pre-Surgical Identification of Muscle Invasive Tumor Evaluations Prior to Planned Cystectomy (INSITE)
Clinical trial INSITE investigates pre-surgical identification of muscle-invasive tumor involvement in patients with urothelial carcinoma sc…
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: A Study of Pemigatinib in Non-muscle Invasive Bladder Cancer Patients With Recurrent Low- or Intermediate-Risk Tumors [Phase 2]
This document provides an update on the Phase 2 trial of pemigatinib in non-muscle invasive bladder cancer patients with recurrent low- or i…
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: A Study of Erdafitinib Versus Investigator Choice of Intravesical Chemotherapy in Participants Who Received Bacillus Calmette-Guérin (BCG) and Recurred With High Risk Non-Muscle-Invasive Bladder Cancer (NMIBC) [Phase 2]
This is a Phase 2 trial comparing Balversa (erdafitinib) to investigator-choice intravesical chemotherapy in patients with high-risk non-mus…
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Proliposomal Intravesical Paclitaxel for Treatment of Low-Grade, Stage Ta, Non Muscle Invasive Bladder Cancer [Phase 1, Phase 2]
A Phase 1/2 trial evaluating proliposomal intravesical paclitaxel for low-grade, Ta non-muscle invasive bladder cancer has completed with tr…
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CLINICAL_TRIALS trial_result · 2025-05-31Clinical Trial Update: BCG for Therapeutic Use Phase I Clinical Trial [Phase 1]
This Phase I study evaluated therapeutic Bacillus Calmette-Guérin for non-muscle invasive bladder cancer and has completed.
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CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: Brazilian Reality of Urinary Bladder Cancers - BRA-BLADDER
AstraZeneca-sponsored BRA-BLADDER study evaluating bladder cancer in Brazil has completed, examining urothelial carcinoma across non-muscle …
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Irinotecan Liposomes Combined with Epirubicin in Recurrent Non-muscle Invasive Bladder Urothelium Carcinoma After Anthracyclines Treatment [Phase 1]
This clinical trial update describes a Phase 1 study of combining irinotecan liposome with epirubicin in patients with recurrent non-muscle …
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Follow up of Intravesical N-803 Plus BCG in BCG-Naive Non-Muscle Invasive Bladder Cancer (NMIBC)
Clinical trial update for intravesical N-803 plus BCG in BCG-naive non-muscle invasive bladder cancer, with the study listed as active but n…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Safety and Toxicity Study of Intravesical Instillation of TARA-002 in Adults with High-grade Non-muscle Invasive Bladder Cancer (Phase 1b) [Phase 1]
This clinical trial update reports safety and toxicity findings from a Phase 1b intravesical instillation study of TARA-002 in adults with h…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Safety and Toxicity Study of Intravesical Instillation of TARA-002 in Adults with High-grade Non-muscle Invasive Bladder Cancer (Phase 1a) [Phase 1]
Phase 1a safety and toxicity study of intravesical instillation of TARA-002 in adults with high-grade non-muscle invasive bladder cancer. Th…
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CLINICAL_TRIALS trial_result · 2025-01-10Clinical Trial Update: Comparison of BCG RIVM and Russian Strains for Treating Non-Muscle-Invasive Bladder Cancer (NMIBC) [Phase 4]
Phase 4 clinical trial comparing BCG RIVM with Russian-strain BCG for non-muscle-invasive bladder cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-11-04Clinical Trial Update: A Phase 3 Single-Arm Study of UGN-102 for Treatment of Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer [Phase 3]
Update on a Phase 3 single-arm trial of UGN-102 for low-grade, intermediate-risk non-muscle invasive bladder cancer; results were posted in …
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: LUMINOS-103: A Basket Trial of Safety & Efficacy of Lerapolturev With or Without Checkpoint Inhibitors [Phase 1, Phase 2]
Terminated basket trial evaluating Lerapolturev with or without checkpoint inhibitors in solid tumors, including bladder cancer and non-musc…
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CLINICAL_TRIALS trial_result · 2024-09-25Clinical Trial Update: Study of CG0070 Given in Combination With Pembrolizumab, in Non-Muscle Invasive Bladder Cancer, Unresponsive to Bacillus Calmette-Guerin [Phase 2]
A Phase 2 study evaluating CG0070 in combination with pembrolizumab for non-muscle invasive bladder cancer unresponsive to Bacillus Calmette…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Feasibility of Home Instillation of UGN-102 for Treatment of Low-Grade (LG) Non-Muscle Invasive Bladder Cancer (NMIBC) [Phase 3]
Phase 3 trial update evaluating feasibility of at-home instillation of UGN-102 for low-grade non-muscle invasive bladder cancer. Results wer…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: SHR-1501 Combined With SHR-2005 for High-Risk Non-Muscle Invasive Bladder Cancer Which is Not Completely Resectable by TURBt [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating SHR-1501 in combination with SHR-2005 for high-risk non-muscle invasive bladder cancer not complete…
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CLINICAL_TRIALS trial_result · 2024-09-03Clinical Trial Update: MK-3475/BCG in High Risk Superficial Bladder Cancer [Phase 1]
Phase 1 trial evaluating pembrolizumab with Bacillus Calmette-Guérin in high-risk non-muscle invasive bladder cancer has completed and resul…
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: A Study of ALT-801 in Patients With Bacillus Calmette-Guerin (BCG) Failure Non-Muscle Invasive Bladder Cancer [Phase 1, Phase 2]
The study ALT-801 in patients with BCG-failure non-muscle invasive bladder cancer (Phase 1/2) was terminated, with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-06-06Clinical Trial Update: A Phase 3 Study of UGN-102 for Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer [Phase 3]
A Phase 3 study of UGN-102 for low-grade intermediate-risk non-muscle invasive bladder cancer was terminated, with results posted on 2024-06…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Multicenter Clinical Trial on the Effectiveness and Safety of Instillation of BCG and Alternative BCG Protocols for Intermediate and High-risk Non-muscle Invasive Bladder Cancer [Phase 3]
Phase 3 multicenter trial evaluating intravesical Bacillus Calmette-Guérin (BCG) and alternative BCG protocols for intermediate and high-ris…
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: Atezolizumab and BCG in High Risk BCG naïve Non-muscle Invasive Bladder Cancer (NMIBC) Patients (BladderGATE) [Phase 1]
Phase 1 clinical trial update for atezolizumab plus Bacillus Calmette-Guérin (BCG) in high-risk BCG-naïve non-muscle invasive bladder cancer…
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CLINICAL_TRIALS trial_result · 2024-03-25Clinical Trial Update: HIVEC in Patients With Non-Muscle-Invasive Bladder Cancer [Phase 3]
A Phase 3 clinical trial update for HIVEC in non-muscle-invasive bladder cancer is currently not yet recruiting.