Non-muscle Invasive Bladder Cancer
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: A Study of RAG-01 in Patients With Non-muscle-invasive Bladder Cancer (NMIBC) Who Have Failed Bacillus Calmette Guérin (BCG) Therapy [Phase 1]
Phase 1 trial to assess the safety and tolerability of RAG-01 in patients with non-muscle-invasive bladder cancer unresponsive to BCG therap…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Study of 2141-V11 in People With Non-muscle Invasive Bladder Cancer That Did Not Respond to Standard Treatment [Phase 1]
This is an early-phase (Phase 1) clinical trial evaluating the investigational drug 2141-V11 in patients with non-muscle invasive bladder ca…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: A Phase I Intravesical PPM Therapy for NMIBC [Phase 1]
This update announces a Phase I intravesical PPM therapy for non-muscle-invasive bladder cancer that is currently recruiting. It represents …
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Safety and Efficacy of FE 999326 Administered Intravesically to Japanese Subjects With High-grade, BCG Unresponsive, Non-muscle Invasive Bladder Cancer (NMIBC) [Phase 3]
Phase 3 study evaluating FE 999326 administered intravesically in Japanese patients with high-grade, BCG-unresponsive non-muscle invasive bl…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: A Phase 1/1b Study of ZH9 Treatment in Patients With Non-Muscle Invasive Bladder Cancer [Phase 1]
A Phase 1/1b study of ZH9 for non-muscle invasive bladder cancer is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Artificial Intelligence Prediction Tool in Non-muscle Invasive Bladder Cancer (NMIBC)
A clinical trial update about an AI-based prediction tool being studied for non-muscle-invasive bladder cancer; the study is currently recru…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: A Study of Intravesical FL115 Alone or in Combination With BCG in Non-Muscle Invasive Bladder Cancer [Phase 1, Phase 2]
This clinical trial update describes an ongoing Phase 1/Phase 2 study evaluating intravesical FL115 alone or in combination with BCG for non…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: Prognostic Effect of Whether Doing PLND During RC for High-risk NMIBC [NA]
Ongoing clinical trial evaluating whether adding pelvic lymph node dissection during radical cystectomy affects prognosis in patients with h…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: RC48 in Combination With Radiotherapy for HER2-Expressing NMIBC Patients [Phase 2]
A Phase 2 trial is evaluating RC48 in combination with radiotherapy for HER2-expressing high-risk non-muscle invasive bladder cancer patient…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: A Study of T3011 in Patients With BCG-Unresponsive NMIBC or BCG-Exposed, Chemotherapy-Unresponsive NMIBC [Phase 2]
A Phase 2 clinical trial of T3011 in patients with nonmuscle-invasive bladder cancer who are BCG-unresponsive or BCG-exposed and chemotherap…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: A Tumor Immune Biomarker Guided Approach for Improving Response to BCG in Patients With High-risk NMIBC. [Phase 1, Phase 2]
This clinical trial explores a tumor immune biomarker-guided strategy to improve response to Bacillus Calmette-Guérin (BCG) therapy in high-…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Observational Clinical Study on High - Risk NMIBC Patients Choosing Trimodality Bladder - Sparing Therapy
An observational study conducted at Peking University First Hospital examines outcomes for patients with high-risk non-muscle invasive bladd…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: A Study Comparing the Necessity of a Second Transurethral Resection in High-Risk Non-Muscle-Invasive Bladder Cancer Patients With Negative Results From Post-Initial Resection Urine Genome-Wide Low-Depth Sequencing [NA]
This clinical trial update outlines an ongoing study evaluating whether a second transurethral resection is necessary in high-risk non-muscl…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Open Label Study to Evaluate the Safety and Efficacy of NDV01 KIT in High Grade NMIBC [Phase 2]
Open-label Phase 2 trial to evaluate the safety and efficacy of NDV01 KIT for high-grade non-muscle-invasive bladder cancer, currently recru…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Bacillus Calmette-Guérin (BCG) and Gemcitabine in People With High-Grade Non-Muscle Invasive Bladder Cancer That Came Back After BCG Treatment [Phase 1, Phase 2]
Clinical trial update for a Phase 1/2 study evaluating the combination of Bacillus Calmette-Guérin (BCG) and Gemcitabine in patients with hi…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Trop2-targeting NIR-II Molecular Probe for Guided Identification of Non-Muscle-Invasive Bladder Cancer
An update on a Trop2-targeting NIR-II molecular probe intended to help guide identification of non-muscle-invasive bladder cancer; the trial…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: T-Control® Safety for Cytostatics Management [NA]
A clinical trial update announces a study evaluating T-Control for safety management of cytostatics in non-muscle-invasive bladder cancer, w…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: A Multicenter Prospective Cohort Study on Monitoring Recurrence of Urothelial Carcinoma Based on Detection of Urinary Microscopic Residual Disease (MRD)
Recruitment is ongoing for a multicenter prospective cohort study evaluating urinary microscopic residual disease as a method to monitor rec…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: Radiotherapy for BCG-unresponsive Non-muscle-invasive Carcinoma in Situ (CIS) Bladder Cancer: an Open-label, Single-arm, Multicentre, Phase 2 Study [NA]
An open-label, single-arm Phase 2 trial is evaluating radiotherapy for BCG-unresponsive non-muscle-invasive bladder cancer with carcinoma in…
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: Anesthesia Modality and Oncologic Outcomes in High-Risk NMIBC: A Randomized Trial [NA]
A randomized trial is investigating how anesthesia modality may influence oncologic outcomes in high-risk non-muscle invasive bladder cancer…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Trial of Encapsulated Rapamycin (eRapa) for Bladder Cancer Prevention [Phase 2]
Phase 2 clinical trial evaluating encapsulated rapamycin (eRapa) for prevention of non-muscle invasive bladder cancer is currently recruitin…
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: AFU Registry of the Therapeutic Management and Follow-up of Non-Muscle-Invasive Bladder Cancer
This registry-based clinical trial in France is evaluating the therapeutic management and follow-up of Non-Muscle-Invasive Bladder Cancer an…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: Immediate Chemotherapy Following Resection for High-Risk Non-Muscle-Invasive Bladder Cancer [NA]
A clinical trial is evaluating immediate chemotherapy after surgical resection for high-risk non-muscle-invasive bladder cancer and is curre…
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: A Bladder-Sparing Treatment Strategies of Large-Volume Non-Muscle-Invasive Bladder Cancer [NA]
This clinical trial update notes that a study evaluating bladder-sparing treatment strategies for large-volume non-muscle-invasive bladder c…
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: Guiding Instillation in Non Muscle-invasive Bladder Cancer Based on Drug Screens in Patient Derived Organoids [Phase 2]
A Phase 2 clinical trial is exploring instillation therapy guided by drug screens in patient-derived organoids for non-muscle-invasive bladd…