Non-muscle Invasive Bladder Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: In-home Intravesical Chemotherapy for the Treatment of Bladder Cancer, INVITE Trial [Phase 1, Phase 2]
The INVITE trial is investigating in-home intravesical chemotherapy for non-muscle invasive bladder cancer and is currently recruiting for P…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Urinary Tumor DNA-Guided Systemic Immunotherapy for Unresectable Very-High-Risk Non-Muscle-Invasive Bladder Cancer [Phase 2]
This Phase 2 clinical trial assesses urinary tumor DNA-guided systemic immunotherapy for unresectable very-high-risk non-muscle-invasive bla…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Dutasteride in Patients With Low Grade Non-muscle Invasive Bladder Cancer [Phase 2]
This document announces a Phase 2 trial evaluating dutasteride in patients with low-grade non-muscle-invasive bladder cancer and notes that …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: ResQ133A-NMIBC: Intravesical Recombinant Mycobacterium (rMBCG) in Participants With NMIBC Eligible to Receive Intravesical Tice BCG [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating intravesical ResQ133A, a recombinant Mycobacterium (rMBCG), for non-muscle invasive bladder cancer in …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Effects of Microbiological and Immunological Factors on the Lower Urinary Tract
A University of Zurich clinical trial update exploring how microbiological and immunological factors influence the lower urinary tract acros…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: ResQ132EX-NMIBC: Expanded Access Use of Recombinant Bacillus Calmette-Guérin in Nonmuscle Invasive Bladder Cancer
Clinical trial update notes expanded-access use of a recombinant Bacillus Calmette-Guérin (ResQ132EX) for Non-muscle invasive bladder cancer…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Phase I/II Study of JL19001 Injection Alone or in Combination With BCG in Subjects With High Risk Non-Muscle Invasive Bladder Cancer. [Phase 1]
This is a registry entry for a Phase I/II study evaluating JL19001 injection alone or in combination with BCG in patients with high-risk non…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Efficacy and Safety of Intravesical TARA-002 Compared With Investigator's Choice of Intravesical Chemotherapy in Participants With BCG-naïve High-grade Non-muscle Invasive Bladder Cancer [Phase 3]
Phase 3 trial update assessing intravesical TARA-002 versus investigator's choice intravesical chemotherapy for BCG-naïve high-grade non-mus…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Guiding Value of Urinary Tumor DNA Testing in Cystoscopy for High-Risk/Very High-Risk Non-Muscle-Invasive Bladder Cancer [NA]
This clinical trial update notes ongoing recruitment for a study evaluating urinary tumor DNA testing to guide cystoscopy in high-risk/non-m…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Study of Cretostimogene Given in Patients With Non-Muscle Invasive Bladder Cancer ,Unresponsive to Bacillus-Calmette-Guerin [Phase 3]
Phase 3 study of Cretostimogene in non-muscle invasive bladder cancer unresponsive to BCG; the trial is currently ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Studying the Relationship of Patient Positioning and Intravesical Bacillus Calmette Guerin Dwell Time to Improve the Treatment of Non-muscle Invasive Bladder Cancer [Phase 4]
A Phase 4 clinical trial in recruitment evaluating how patient positioning and intravesical dwell time of Bacillus Calmette-Guérin affect tr…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: PLZ4-Coated Paclitaxel-Loaded Micelles for the Treatment of Patients With Recurrent or Refractory Non-Muscle Invasive Bladder Cancer [Phase 1]
This document reports an ongoing Phase 1 clinical trial by the University of California, Davis evaluating PLZ4-coated paclitaxel-loaded mice…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Home-Based Physical Activity Program With Digital App Versus Health Education Group for Improving Physical Activity Among Patients With Non-muscle Invasive Bladder Cancer, The EMPOWER Trial [NA]
A clinical trial compares a home-based physical activity program using a digital app to health education in patients with localized non-musc…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: IDO and PD-L1 Peptide Based Immune-Modulatory Therapeutic (IO102-IO103) in Combination With Pembrolizumab for BCG-Unresponsive or Intolerant, Non-Muscle Invasive Bladder Cancer [Phase 1]
Phase 1 clinical trial evaluating IO102-IO103 in combination with pembrolizumab for high-risk non-muscle invasive bladder cancer that is unr…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: A Study of NDV-01 (Sustained-release Gemcitabine-docetaxel) in Participants With Non-muscle Invasive Bladder Cancer [Phase 3]
Relmada Therapeutics is evaluating NDV-01, a sustained-release gemcitabine-docetaxel formulation, in Phase 3 for non-muscle invasive bladder…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: BCG in Combination With Durvalumab in Adult BCG-naïve, High-risk NMIBC Participants [Phase 3]
Phase 3 clinical trial update on combining durvalumab with BCG for adults with high-risk non-muscle invasive bladder cancer who are BCG-naïv…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Guiding Value of Urinary Tumor DNA Testing in Repeat Transurethral Resection of Non-Muscle-Invasive Bladder Cancer [NA]
This clinical trial update discusses the potential value of urinary tumor DNA testing for guiding repeat transurethral resection decisions i…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: The Study is to Evaluate the Safety and Tolerability of SPGL008 Alone or in Combination With BCG in the Patients With NMIBC, and to Determine the RP2D of SPGL008 Alone or in Combination With BCG.To Evaluate the Preliminary Efficacy of SPGL008 Alone or in Combination With BCG. [Phase 1, Phase 2]
A Phase 1/2 trial evaluating SPGL008 alone or with BCG for non-muscle invasive bladder cancer to assess safety, determine the RP2D, and expl…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: The Guiding Value of Liquid Biopsy Based on Urinary Tumor DNA/RNA in the Second Transurethral Resection of High-risk Non-muscle Invasive Bladder Cancer
This clinical trial update describes ongoing recruitment for a study assessing urinary tumor DNA/RNA–based liquid biopsy during a second tra…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Intravesical Gem/Doce in Patients With NMIBC [Phase 2]
Phase 2 clinical trial evaluating intravesical gemcitabine and docetaxel for non-muscle invasive bladder cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Study of Intravesical SHR-1501 Combination With BCG Versus Investigator-selected Chemotherapy in Subjects With BCG-unresponsive NMIBC [Phase 3]
Phase 3 trial evaluating intravesical SHR-1501 combined with BCG versus investigator-selected chemotherapy in patients with BCG-unresponsive…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: A Study of STM-416 Administered to Patients Undergoing TURBT for Recurrent Bladder Cancer [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating STM-416 in patients undergoing TURBT for recurrent non-muscle-invasive bladder cancer; recruitment is cu…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Patients With Bladder Cancer (MK-2870-027) [Phase 1, Phase 2]
Merck is conducting a Phase 1/2 clinical trial of Sacituzumab Tirumotecan (MK-2870) for non-muscle invasive bladder cancer, and the study is…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Intravesical Chemotherapy in Combination With Systemic Pembrolizumab in NMIBC Unresponsive or Exposed to BCG Therapy [Phase 2]
Phase 2 clinical trial investigating intravesical chemotherapy in combination with systemic pembrolizumab for non-muscle-invasive bladder ca…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Study to Determine Possible Effects of Apalutamide, Compared to Placebo, on EGFR Expression in Patients With Non-muscle Invasive Bladder Cancer [Phase 1]
Phase 1 trial to evaluate the potential effect of apalutamide on EGFR expression in non-muscle invasive bladder cancer; not yet recruiting.