Non-hodgkin Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-08-03Clinical Trial Update: FNA Tumor Sampling for CD137 Modulation: A Pilot Study
Termination update for a pilot study evaluating FNA tumor sampling for CD137 modulation in cancer patients.
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CLINICAL_TRIALS trial_result · 2017-08-01Clinical Trial Update: Clinical And Economic Impact Of Upfront Plerixafor In Autologous Transplantation [Phase 2]
Phase 2 clinical trial update evaluating upfront plerixafor in autologous transplantation and its clinical and economic impact in Non-Hodgki…
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CLINICAL_TRIALS trial_result · 2017-07-26Clinical Trial Update: A Phase I, Dose-Escalation Study to Assess the Safety and Biological Activity of Recombinant Human Interleukin-18 [Phase 1]
Phase I dose-escalation study evaluating the safety and biological activity of recombinant human interleukin-18 in Non-Hodgkin lymphoma; the…
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CLINICAL_TRIALS trial_result · 2017-07-25Clinical Trial Update: Safety and Efficacy of Iodine-131 Anti-B1 Antibody for Non Hodgkin's Lymphoma (NHL) Patients With Greater Than 25% Bone Marrow Involvement [Phase 1]
Phase 1 trial assessing the safety and efficacy of an iodine-131 labeled anti-B1 antibody in non-Hodgkin lymphoma patients with >25% bone ma…
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CLINICAL_TRIALS research · 2017-07-19Clinical Trial Update: Study of Safety,Efficacy and Pharmacokinetics of CT-1530 in Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, and Waldenstrom's Macroglobulinemia [Phase 1, Phase 2]
Clinical trial update describing a Phase 1/Phase 2 study of CT-1530 in relapsed or refractory B-cell non-Hodgkin lymphoma, chronic lymphocyt…
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CLINICAL_TRIALS trial_result · 2017-07-18Clinical Trial Update: Non-inferiority Study of XM02 Filgrastim (Granix) and Filgrastim (Neupogen) in Combination With Plerixafor for Autologous Stem Cell Mobilization in Patients With Multiple Myeloma or Non-Hodgkin Lymphoma [Phase 2]
A Phase 2 non-inferiority trial comparing XM02 (Granix) and filgrastim (Neupogen) when used with plerixafor for autologous stem cell mobiliz…
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CLINICAL_TRIALS trial_result · 2017-07-17Clinical Trial Update: Preservation of Ovarian Function After Hematopoietic Cell Transplant [Phase 2]
Phase 2 trial investigating preservation of ovarian function after hematopoietic cell transplantation in patients with hematologic cancers; …
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CLINICAL_TRIALS trial_result · 2017-07-14Clinical Trial Update: Rituximab and Liposomal Doxorubicin in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma [Phase 1, Phase 2]
Clinical trial evaluating the combination of rituximab and liposomal doxorubicin in relapsed or refractory non-Hodgkin lymphoma across Phase…
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CLINICAL_TRIALS research · 2017-07-07Clinical Trial Update: Assessment of the Minimal Residual Disease in DLBCL From Cell-free Circulating DNA by NGS [NA]
Completed clinical trial evaluating minimal residual disease in diffuse large B-cell lymphoma using cell-free circulating DNA detected by ne…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Rituximab, Combination Chemotherapy, Filgrastim (G-CSF), and Plerixafor in Treating Patients With Non-Hodgkin Lymphoma Undergoing Mobilization of Autologous Peripheral Blood Stem Cells [Phase 2]
Phase 2 trial investigating rituximab with combination chemotherapy, G-CSF, and plerixafor for autologous stem cell mobilization in non-Hodg…
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: Sequential Infusion of Anti-CD19 and Anti-CD20 CAR-T Cells Against Relapsed and Refractory B-cell Lymphoma [Phase 1, Phase 2]
Phase 1/2 study assessing sequential infusion of CD19- and CD20-directed CAR-T cells in relapsed or refractory B-cell lymphoma.
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Phase 1/1b Study of TRU-016 in Patients With Previously Treated CLL or Select Subtypes of Non-Hodgkin's Lymphoma [Phase 1]
The Phase 1/1b study of TRU-016 in patients with previously treated Chronic Lymphocytic Leukemia or select subtypes of Non-Hodgkin's Lymphom…
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CLINICAL_TRIALS withdrawal · 2017-06-27Clinical Trial Update: Study of Pembrolizumab With Chemotherapy in Patients With Advanced Lymphoma (PembroHeme) [Phase 1, Phase 2]
The Phase 1/2 trial assessing pembrolizumab in combination with chemotherapy for advanced lymphoma has been withdrawn.
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CLINICAL_TRIALS research · 2017-06-26Clinical Trial Update: Study to Assess the Pharmacokinetics and Pharmacodynamics of GSK461364 in Subjects With Non-Hodgkins Lymphoma [Phase 1]
Phase 1 pharmacokinetics and pharmacodynamics study of GSK461364 in subjects with Non-Hodgkin lymphoma has completed.
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CLINICAL_TRIALS research · 2017-06-26Clinical Trial Update: Non-Hodgkin Lymphoma - Observational Epidemiological and Clinical Study (NiHiL)
An ongoing observational study in the Czech Republic examining the epidemiology and clinical aspects of Non-Hodgkin lymphoma.
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FDA approval · 2017-06-22FDA Approved: RITUXAN HYCELA — Original Application (Genentech, Inc.)
FDA approved RITUXAN HYCELA (rituximab and hyaluronidase) under an Original Application by Genentech. The subcutaneous formulation provides …
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FDA label_change · 2017-06-22FDA Approved: RITUXAN HYCELA — Supplemental Application (Genentech, Inc.)
FDA approved a supplemental application for Rituxan Hycela (rituximab and hyaluronidase) by Genentech, updating the labeling for this subcut…
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CLINICAL_TRIALS trial_result · 2017-06-20Clinical Trial Update: A Dose-escalation Study of MK-8776 (SCH 900776) With and Without Gemcitabine in Participants With Solid Tumors or Lymphoma (MK-8776-002/P05248) [Phase 1]
Phase 1 dose-escalation study of MK-8776 (SCH 900776) with and without gemcitabine in solid tumors or lymphoma completed; results posted in …
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CLINICAL_TRIALS research · 2017-06-20Clinical Trial Update: A Study of Anti-CD19 CAR-T Cell Immunotherapy for Refractory /Relapsed B Cell Malignancies [Phase 1, Phase 2]
This clinical trial update reports on a Phase 1/Phase 2 study of an anti-CD19 CAR-T cell therapy for refractory/relapsed B-cell malignancies…
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CLINICAL_TRIALS trial_result · 2017-06-16Clinical Trial Update: A Study of Escalating Doses of Polatuzumab Vedotin in Participants With Relapsed or Refractory B-Cell Non-Hodgkins Lymphoma and Chronic Lymphocytic Leukemia and Polatuzumab Vedotin in Combination With Rituximab in Participants With Relapsed or Refractory B-Cell Non-Hodgkins Lymphoma [Phase 1]
This Phase 1 trial investigates escalating doses of polatuzumab vedotin in relapsed or refractory B-cell non-Hodgkin lymphoma and chronic ly…
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CLINICAL_TRIALS trial_result · 2017-06-16Clinical Trial Update: Copanlisib Pharmacodynamic Study [Phase 1]
Phase 1 pharmacodynamic study of copanlisib in non-Hodgkin lymphoma has completed. The document indicates this early-stage trial produced ph…
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: A Study of Obinutuzumab (RO5072759) Plus Chemotherapy in Comparison With Rituximab Plus Chemotherapy Followed by Obinutuzumab or Rituximab Maintenance in Patients With Untreated Advanced Indolent Non-Hodgkin's Lymphoma (GALLIUM) [Phase 3]
Phase 3 trial comparing obinutuzumab plus chemotherapy vs rituximab plus chemotherapy in untreated advanced indolent non-Hodgkin's lymphoma;…
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CLINICAL_TRIALS trial_result · 2017-06-06Clinical Trial Update: Study Evaluating AMD3100 for Transplantation of Sibling Donor Stem Cells in Patients With Hematological Malignancies [Phase 1, Phase 2]
Phase 1/2 study evaluating plerixafor (AMD3100) as a stem cell mobilizer for transplantation from a sibling donor in various hematologic mal…
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CLINICAL_TRIALS trial_result · 2017-06-06Clinical Trial Update: A Study of PRO95780 in Combination With Rituximab in Patients With Non-Hodgkin's Lymphoma That Has Progressed Following Previous Rituximab Therapy (APM4083g) [Phase 2]
Phase 2 study evaluating PRO95780 in combination with Rituximab in patients with Non-Hodgkin lymphoma that progressed after prior Rituximab …
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CLINICAL_TRIALS trial_result · 2017-06-05Clinical Trial Update: Sirolimus & Mycophenolate Mofetil as GvHD Prophylaxis in Myeloablative, Matched Related Donor HCT [Phase 2]
Phase 2 trial of sirolimus and mycophenolate mofetil as graft-versus-host disease prophylaxis in myeloablative, matched related donor hemato…