Non-hodgkin Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: A Phase 1 Study of JV-213 Autologous CD79b-targeting Chimeric Antigen Receptor T-cell Therapy in Adults With Relapsed or Refractory B-cell Lymphomas [Phase 1]
A Phase 1 study evaluating JV-213, an autologous CD79b-targeting CAR T-cell therapy, in adults with relapsed or refractory B-cell lymphomas;…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: huCART19-IL18 in CD19+ Cancers [Phase 1]
Phase 1 clinical trial of huCART19-IL18 for CD19+ cancers is currently ACTIVE_NOT_RECRUITING, sponsored by the University of Pennsylvania, i…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Long-term Follow-up Study of Patients Receiving CAR-T Cells
This clinical trial update outlines a long-term follow-up study of patients who received CAR-T cell therapy. Sponsored by the Medical Colleg…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Personalized NK Cell Therapy in CBT [Phase 2]
A Phase 2 trial from MD Anderson is evaluating personalized NK cell therapy across several hematologic cancers. The study is currently recru…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Rituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL) [Phase 1]
Phase 1 clinical trial evaluating the combination of Rituximab and Tafasitamab with allogeneic NK cells in relapsed/refractory B-cell non-Ho…
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CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: A Study to Assess Long-term Safety of Tazemetostat in Adult Participants of All Ages With Any Disease Treated With Tazemetostat in a Previous Clinical Study [Phase 1, Phase 2]
This document reports the completion of a long-term safety study of tazemetostat in adults who previously received the drug in earlier trial…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: A Study Evaluating APG-115 as a Single Agent or in Combination With APG-2575 in Subjects With R/R T-PLL and NHL [Phase 2]
A Phase 2 clinical trial update indicates Ascentage Pharma is evaluating APG-115 alone or with APG-2575 in relapsed/refractory T-cell prolym…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Auto Stem Cell Transplant for Lymphoma Patients [Phase 2]
This Phase 2 clinical trial registry entry describes autologous stem cell transplantation as a treatment approach for non-Hodgkin lymphoma a…
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CLINICAL_TRIALS trial_result · 2025-11-03Clinical Trial Update: Nivolumab for Relapsed, Refractory, or Detectable Disease Post Chimeric Antigen Receptor T-cell Treatment in Patients With Hematologic Malignancies [Phase 2]
Phase 2 trial evaluating nivolumab in patients with hematologic malignancies after CAR-T therapy; results have been posted with the study cu…
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: Autologous/Allogeneic TGFbeta-resistant LMP-specific CTL, Lymphoma (TGF-beta) [Phase 1]
Phase 1 trial evaluating autologous/allogeneic TGF-beta-resistant LMP-specific cytotoxic T lymphocytes for lymphoma; the study is active but…
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CLINICAL_TRIALS trial_result · 2025-10-30Clinical Trial Update: Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in With High-Risk Hematologic Malignancies [Phase 2]
Phase 2 trial evaluating reduced-intensity conditioning before allogeneic donor stem cell transplantation in patients with high-risk hematol…
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CLINICAL_TRIALS trial_result · 2025-10-30Clinical Trial Update: Extended Treatment Protocol for Subjects Continuing to Benefit From Ibrutinib. [Phase 4]
This Phase 4 trial update describes extending ibrutinib treatment for patients who continue to benefit from the therapy.
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CLINICAL_TRIALS research · 2025-10-30Clinical Trial Update: Two Step Haplo With Radiation Conditioning [Phase 2]
Phase 2 clinical trial update describing two-step haploidentical transplantation with radiation conditioning for hematologic diseases, curre…
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: Resiliency in Older Adults Undergoing Bone Marrow Transplant
A completed clinical trial update from Johns Hopkins on resiliency in older adults undergoing bone marrow transplant for hematologic cancers…
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CLINICAL_TRIALS trial_result · 2025-10-24Clinical Trial Update: A Safety and Efficacy Study Evaluating CTX110 in Subjects With Relapsed or Refractory B-Cell Malignancies (CARBON) [Phase 1, Phase 2]
This clinical trial update reports safety and efficacy data for CTX110 in relapsed or refractory B-cell malignancies, including Non-Hodgkin …
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating larotrectinib in patients with NTRK gene fusions has posted results; the study remains active but n…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: 'Re-Priming' RT After Incomplete Response to CAR-T in R/R NHL [Phase 1, Phase 2]
A Phase 1/2 trial evaluating re-priming radiotherapy after incomplete response to CAR-T therapy in relapsed/refractory non-Hodgkin lymphoma …
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors [Phase 1]
Phase 1 pediatric trial evaluating alpha/beta CD19+ depleted haploidentical transplantation in combination with Zoledronic acid (Zometa) for…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: Study of Acalabrutinib Alone or in Combination Therapy in Subjects With B-cell Non-Hodgkin Lymphoma [Phase 1, Phase 2]
Acalabrutinib is being studied in Phase 1/2 as a single agent or in combination therapy for B-cell non-Hodgkin lymphoma, with results posted…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Family Study of Lymphoproliferative Disorders
A Mayo Clinic-led clinical trial is a family study investigating lymphoproliferative disorders, currently in the recruitment phase.
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: Safety and Preliminary Efficacy of JBH492 Monotherapy in Patients With CLL and NHL [Phase 1]
Phase 1 trial of JBH492 as monotherapy in chronic lymphocytic leukemia and non-Hodgkin lymphoma reports safety and preliminary efficacy; the…
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: Study to Investigate the Safety and Tolerability of Odronextamab in Patients With CD20+ B-Cell Malignancies [Phase 1]
Phase 1 study of odronextamab in CD20+ B-cell malignancies completed; the trial reported safety and tolerability data in diseases including …
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: A Study of JNJ-75348780 in Participants With Non-Hodgkin Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL) [Phase 1]
This clinical trial update reports the Phase 1 study of JNJ-75348780 in participants with Non-Hodgkin lymphoma and chronic lymphocytic leuke…
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: VOB560-MIK665 Combination First in Human Trial in Patients With Hematological Malignancies (Relapsed/Refractory Non-Hodgkin Lymphoma, Relapsed/Refractory Acute Myeloid Leukemia, or Relapsed/Refractory Multiple Myeloma) [Phase 1]
This update reports termination of the first-in-human Phase 1 trial of the VOB560-MIK665 combination in relapsed/refractory hematologic mali…
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: A Study of TLN-254 in Participants With Relapsed or Refractory T-cell Lymphoma [Phase 1]
Treeline Biosciences is conducting a Phase 1 study of TLN-254 in participants with relapsed or refractory T-cell lymphoma, currently recruit…