Non-hodgkin Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-10-24Clinical Trial Update: A Safety and Efficacy Study Evaluating CTX110 in Subjects With Relapsed or Refractory B-Cell Malignancies (CARBON) [Phase 1, Phase 2]
This clinical trial update reports safety and efficacy data for CTX110 in relapsed or refractory B-cell malignancies, including Non-Hodgkin …
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating larotrectinib in patients with NTRK gene fusions has posted results; the study remains active but n…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: 'Re-Priming' RT After Incomplete Response to CAR-T in R/R NHL [Phase 1, Phase 2]
A Phase 1/2 trial evaluating re-priming radiotherapy after incomplete response to CAR-T therapy in relapsed/refractory non-Hodgkin lymphoma …
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: Study of Acalabrutinib Alone or in Combination Therapy in Subjects With B-cell Non-Hodgkin Lymphoma [Phase 1, Phase 2]
Acalabrutinib is being studied in Phase 1/2 as a single agent or in combination therapy for B-cell non-Hodgkin lymphoma, with results posted…
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: Safety and Preliminary Efficacy of JBH492 Monotherapy in Patients With CLL and NHL [Phase 1]
Phase 1 trial of JBH492 as monotherapy in chronic lymphocytic leukemia and non-Hodgkin lymphoma reports safety and preliminary efficacy; the…
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: Study to Investigate the Safety and Tolerability of Odronextamab in Patients With CD20+ B-Cell Malignancies [Phase 1]
Phase 1 study of odronextamab in CD20+ B-cell malignancies completed; the trial reported safety and tolerability data in diseases including …
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: VOB560-MIK665 Combination First in Human Trial in Patients With Hematological Malignancies (Relapsed/Refractory Non-Hodgkin Lymphoma, Relapsed/Refractory Acute Myeloid Leukemia, or Relapsed/Refractory Multiple Myeloma) [Phase 1]
This update reports termination of the first-in-human Phase 1 trial of the VOB560-MIK665 combination in relapsed/refractory hematologic mali…
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CLINICAL_TRIALS trial_result · 2025-10-06Clinical Trial Update: Cellular Immunotherapy Following Chemotherapy in Treating Patients With Recurrent Non-Hodgkin Lymphomas, Chronic Lymphocytic Leukemia, or B-Cell Prolymphocytic Leukemia [Phase 1]
Phase 1 trial evaluating cellular immunotherapy after chemotherapy in patients with recurrent B-cell lymphoid cancers, including Non-Hodgkin…
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CLINICAL_TRIALS trial_result · 2025-10-06Clinical Trial Update: Telehealth Exercise Intervention to Improve Cardiovascular Health in Lymphoma Survivors, TECHS Trial [NA]
Clinical trial update confirming completion of the TECHS trial, which tested a telehealth exercise program to improve cardiovascular health …
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Study Evaluating SC291 in Subjects With r/r B-cell Malignancies (ARDENT) [Phase 1]
Sana Biotechnology's investigational candidate SC291 is being studied in a Phase 1 ARDENT trial for relapsed/refractory B-cell malignancies,…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study
The CREST study update shows the cardiovascular reserve evaluation trial in transplant survivors is currently active but not recruiting, spo…
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CLINICAL_TRIALS trial_result · 2025-09-23Clinical Trial Update: A First-in-human Trial of GEN3017 in Hodgkin Lymphoma and Non-Hodgkin Lymphoma [Phase 1, Phase 2]
A first-in-human phase 1/2 trial of GEN3017 in classical Hodgkin lymphoma and non-Hodgkin lymphoma was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy [Phase 2]
A Phase 2 clinical trial update notes evaluation of siltuximab for treating cytokine release syndrome (CRS) and ICANS related to CAR-T cell …
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: A Safety, Efficacy and Pharmacokinetic Study of BTCT4465A (Mosunetuzumab) as a Single Agent and Combined With Atezolizumab in Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL) [Phase 1, Phase 2]
This clinical trial update reports on safety, efficacy, and pharmacokinetics of mosunetuzumab as a single agent and with atezolizumab in chr…
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: TmCD19-IL18 in CD19+ Cancers [Phase 1]
A Phase 1 clinical trial evaluating TmCD19-IL18 for CD19-positive cancers, with Non-Hodgkin lymphoma as the condition, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Notch 1 Mutation in Chronic Lymphocytic Leukemia and Non-Hodgkin's Lymphoma Patient
This ClinicalTrials.gov entry (NCT07157579) from Sohag University notes a study on Notch 1 mutation in chronic lymphocytic leukemia and non-…
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CLINICAL_TRIALS trial_result · 2025-08-28Clinical Trial Update: A Study to Evaluate AB308 in Combination With AB122 in Participants With Advanced Malignancies [Phase 1]
The Phase 1 study evaluating AB308 in combination with AB122 in participants with advanced malignancies has been completed.
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Ciprofloxacin vs Ceftazidime for Empirical Treatment of High-Risk Neutropenic Fever in Children With Hematologic Malignancies [Phase 4]
Phase 4 trial comparing ciprofloxacin to ceftazidime as empirical therapy for high-risk febrile neutropenia in children with hematologic can…
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: A Study of JNJ-64264681 in Participants With Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia [Phase 1]
This update reports the completion of a Phase 1 study evaluating JNJ-64264681 in participants with non-Hodgkin lymphoma and chronic lymphocy…
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: A Study of JNJ-64264681 and JNJ-67856633 in Participants With Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia [Phase 1]
This is a completed Phase 1 clinical trial update for Janssen investigational agents JNJ-64264681 and JNJ-67856633 in participants with Non-…
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: A Study of the MALT1 Inhibitor JNJ-67856633 and Ibrutinib in Combination in B-cell NHL and CLL [Phase 1]
A Phase 1 study evaluated the combination of the MALT1 inhibitor JNJ-67856633 with Ibrutinib in patients with chronic lymphocytic leukemia a…
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: Safety and Preliminary Efficacy of MT-601 in Patients With Relapsed/Refractory Lymphoma [Phase 1]
Phase 1 trial of MT-601 in relapsed/refractory lymphoma shows safety and preliminary efficacy signals in both non-Hodgkin lymphoma and Hodgk…
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CLINICAL_TRIALS trial_result · 2025-08-19Clinical Trial Update: Phase 1-2 MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell [Phase 1, Phase 2]
A completed Phase 1/2 study from Stanford evaluated a haploidentical hematopoietic cell transplantation approach using a T-cell depleted gra…
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: Dose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies [Phase 1]
Phase 1 dose-escalation and expansion study of intratumoral mRNA-2752 in advanced malignancies has completed, with expansion cohorts in seve…
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: Safety and Feasibility of CD19 CAR T Cells Using CliniMACS Prodigy for Relapsed/Refractory CD19 Positive ALL and NHL [EARLY_Phase 1]
An early-phase trial evaluating the safety and feasibility of CD19 CAR T cells manufactured with the CliniMACS Prodigy platform for relapsed…