Non-alcoholic Steatohepatitis
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CLINICAL_TRIALS trial_result · 2020-02-21Clinical Trial Update: A Phase ll Study of IMM-124E for Patients With Non-alcoholic Steatohepatitis [Phase 2]
A Phase 2 clinical trial of IMM-124E for non-alcoholic steatohepatitis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-02-19Clinical Trial Update: A Sub-study of BMS-986036 in Subjects With Non-Alcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 sub-study update for the BMS-986036 program in non-alcoholic steatohepatitis (NASH) with completed status and results posted.
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CLINICAL_TRIALS trial_result · 2020-01-28Clinical Trial Update: A Study of BMS-986036 in Subjects With Non-Alcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 trial of BMS-986036 in non-alcoholic steatohepatitis (NASH) has completed, with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2019-11-26Clinical Trial Update: Safety, Tolerability, Pharmacokinetics and Efficacy of LMB763 in Patients With NASH [Phase 2]
Phase 2 trial update for LMB763 in non-alcoholic steatohepatitis (NASH) has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2019-11-25Clinical Trial Update: Volixibat (SHP626) in the Treatment of Adults With Nonalcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 trial of Volixibat (SHP626) in adults with nonalcoholic steatohepatitis was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-09-06Clinical Trial Update: Efficacy and Safety of MT-3995 in Patients With Non-Alcoholic Steatohepatitis(NASH) [Phase 2]
Phase 2 clinical trial update on MT-3995 for non-alcoholic steatohepatitis (NASH) reporting efficacy and safety results.
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CLINICAL_TRIALS trial_result · 2019-08-19Clinical Trial Update: Emricasan, a Caspase Inhibitor, for Evaluation in Subjects With Non-Alcoholic Steatohepatitis (NASH) Fibrosis [Phase 2]
A Phase 2 clinical trial evaluating emricasan, a caspase inhibitor, for non-alcoholic steatohepatitis with fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2019-06-26Clinical Trial Update: Safety, Tolerability, and Efficacy of GS-4997 Alone or in Combination With Simtuzumab (SIM) in Adults With Nonalcoholic Steatohepatitis (NASH) and Fibrosis Stages F2-F3 [Phase 2]
Phase 2 trial assessing GS-4997 alone or with simtuzumab in adults with NASH and fibrosis (F2-F3); study completed with results posted in 20…
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CLINICAL_TRIALS trial_result · 2019-04-18Clinical Trial Update: EUS Guided Core Liver Biopsy and IGB Placement for the Diagnosis and Management of NASH and Obesity [NA]
A completed clinical trial investigating EUS-guided core liver biopsy and intragastric balloon placement for diagnosing and managing obesity…
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CLINICAL_TRIALS trial_result · 2019-03-19Clinical Trial Update: Emricasan, a Caspase Inhibitor, for Treatment of Subjects With Decompensated NASH Cirrhosis [Phase 2]
Phase 2 clinical trial update for emricasan, a caspase inhibitor, in subjects with decompensated cirrhosis due to non-alcoholic steatohepati…
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CLINICAL_TRIALS trial_result · 2019-03-19Clinical Trial Update: BREATHID Octanoate Breath Test With or Without Methacetin Breath Test for Correlation With Biopsy in NASH [Phase 2]
Phase 2 clinical trial evaluating BREATHID Octanoate Breath Test with or without Methacetin Breath Test for correlation with biopsy in non-a…
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CLINICAL_TRIALS trial_result · 2018-05-04Clinical Trial Update: SGLT2 Inhibitors and Metformin on Metabolism and Non-Alcoholic SteatoHepatitis [Phase 1]
This update notes a completed Phase 1 trial evaluating the metabolic effects of SGLT2 inhibitors in combination with metformin for non-alcoh…
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CLINICAL_TRIALS trial_result · 2018-05-04Clinical Trial Update: The Effect of HIT in Patients With Non-alcoholic Fatty Liver Disease/Steatohepatitis [NA]
A completed clinical trial evaluated the effect of HIT in patients with non-alcoholic fatty liver disease and non-alcoholic steatohepatitis,…
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CLINICAL_TRIALS trial_result · 2018-01-30Clinical Trial Update: Comparing Effects of Liraglutide and Bariatric Surgery on Weight Loss, Liver Function, Body Composition, Insulin Resistance, Endothelial Function and Biomarkers of Non-alcoholic Steatohepatitis (NASH) in Obese Asian Adults [Phase 3]
A Phase 3 trial comparing liraglutide versus bariatric surgery for weight loss and metabolic endpoints in obese Asian adults with NAFLD/NASH…
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CLINICAL_TRIALS trial_result · 2017-08-21Clinical Trial Update: Drug-drug Interaction Study Between EDP-305, Midazolam, Caffeine and Rosuvastatin in Healthy Volunteers. [Phase 1]
Phase 1 drug-drug interaction study assessed interactions between EDP-305 and midazolam, caffeine, and rosuvastatin in healthy volunteers; t…
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CLINICAL_TRIALS trial_result · 2017-08-03Clinical Trial Update: Mediterranean Lifestyle Intervention in Patients With Non-alcoholic Fatty Liver Disease [NA]
A completed clinical trial evaluating a Mediterranean lifestyle intervention in patients with non-alcoholic fatty liver disease (NAFLD) and …
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CLINICAL_TRIALS trial_result · 2017-06-12Clinical Trial Update: Histological Improvement of NASH With Prebiotic [NA]
A completed clinical trial investigated histological improvement in non-alcoholic fatty liver disease (NASH) using a prebiotic therapy, sugg…
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CLINICAL_TRIALS trial_result · 2017-05-05Clinical Trial Update: Effect of Non-Alcoholic Steatohepatitis (NASH) on the Pharmacokinetics of 99mTechnetium-Mebrofenin [Phase 1]
A Phase 1 study evaluated how non-alcoholic steatohepatitis affects the pharmacokinetics of the radiopharmaceutical Technetium-99m mebrofeni…
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CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: Safety and Tolerability Study of SHP626 in Overweight and Obese Adults [Phase 1]
Phase 1 safety and tolerability trial of SHP626 in overweight and obese adults with non-alcoholic steatohepatitis has completed with posted …
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CLINICAL_TRIALS trial_result · 2016-10-25Clinical Trial Update: Treatment of Non-alcoholic Steatohepatitis (NASH) Patients With Vitamin D [Phase 2]
A Phase 2 trial evaluating the use of Vitamin D for treatment of non-alcoholic steatohepatitis has completed.
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CLINICAL_TRIALS trial_result · 2016-08-18Clinical Trial Update: Relationship of Metabolic Abnormalities to Hepatic Steatosis in HIV
A completed clinical trial evaluating the relationship between metabolic abnormalities and hepatic steatosis in people with HIV.
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CLINICAL_TRIALS trial_result · 2016-05-12Clinical Trial Update: Effect of Fish-oil on Non-alcoholic Steatohepatitis (NASH) [Phase 2]
A Phase 2 clinical trial evaluating the effect of fish oil on non-alcoholic steatohepatitis has completed.
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CLINICAL_TRIALS trial_result · 2016-01-29Clinical Trial Update: Phase II Trial of Silymarin for Non-Cirrhotic Patients With Non-Alcoholic Steatohepatitis [Phase 2]
Phase II trial of silymarin for non-cirrhotic patients with non-alcoholic steatohepatitis has completed; results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-01-14Clinical Trial Update: DHA and Vitamin D in Children With Biopsy-proven NAFLD [Phase 3]
A Phase 3 clinical trial evaluating DHA and vitamin D in children with biopsy-confirmed non-alcoholic fatty liver disease (NAFLD) and non-al…
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CLINICAL_TRIALS trial_result · 2015-09-28Clinical Trial Update: Impact of Fructose Consumption on Intestinal Permeability in Non-alcoholic Fatty Liver Disease (NAFLD) - a Pilot Study. [NA]
A pilot clinical trial investigates how fructose intake affects intestinal permeability in people with non-alcoholic fatty liver disease and…