Non-alcoholic Steatohepatitis
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CLINICAL_TRIALS trial_result · 2022-11-03Clinical Trial Update: Phase IIb Study to Evaluate the Efficacy and Safety of GFT505 Versus Placebo in Patients With Non-Alcoholic Steatohepatitis (NASH) [Phase 2]
Phase IIb study evaluating GFT505 vs placebo in non-alcoholic steatohepatitis (NASH) has completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-06-30Clinical Trial Update: An Evaluation of the Safety and Efficacy of Nitazoxanide on Collagen Turnover in NASH Patients With Fibrosis [Phase 2]
Phase 2 trial evaluating nitazoxanide for safety and efficacy in reducing collagen turnover in NASH patients with fibrosis; study completed …
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CLINICAL_TRIALS trial_result · 2022-05-31Clinical Trial Update: A Study to Evaluate Safety and Pharmacodynamic Efficacy of 0382 in Obese Subjects With NAFLD/NASH. [Phase 2]
Phase 2 clinical trial assessing safety and pharmacodynamic efficacy of 0382 in adults with NAFLD/NASH has completed with results posted in …
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CLINICAL_TRIALS trial_result · 2022-05-11Clinical Trial Update: A Double-blind Study to Assess 2 Doses of an Investigational Product for 16 Weeks in Participants With Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus [Phase 2]
Phase 2 double-blind trial evaluating two doses of an investigational product for 16 weeks in adults with non-alcoholic steatohepatitis and …
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CLINICAL_TRIALS trial_result · 2022-05-03Clinical Trial Update: Structured Mobile Technology Based Lifestyle Program vs Usual Care for Patients With Non-alcoholic Fatty Liver Disease [NA]
A completed clinical trial comparing a structured mobile technology–based lifestyle program to usual care for non-alcoholic fatty liver dise…
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CLINICAL_TRIALS trial_result · 2022-04-04Clinical Trial Update: Use of a Novel Drug in People With Non-alcoholic Steatohepatitis (NASH) or Non-alcoholic Fatty Liver Disease (NAFLD) [Phase 2]
A Phase 2 trial investigating a novel drug for non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) has termin…
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CLINICAL_TRIALS trial_result · 2022-01-14Clinical Trial Update: Emricasan, an Oral Caspase Inhibitor, in Subjects With NASH Cirrhosis and Severe Portal Hypertension [Phase 2]
Phase 2 trial of emricasan, an oral caspase inhibitor, in subjects with NASH cirrhosis and severe portal hypertension has completed with res…
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CLINICAL_TRIALS trial_result · 2021-11-12Clinical Trial Update: Study of Safety, Tolerability, and Efficacy of a Combination Treatment of LJN452 and CVC in Adult Patients With NASH and Liver Fibrosis [Phase 2]
Phase 2 study evaluating safety, tolerability, and efficacy of LJN452 combined with CVC in adult patients with non-alcoholic steatohepatitis…
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CLINICAL_TRIALS trial_result · 2021-10-28Clinical Trial Update: Elafibranor, PK and Safety in Children and Adolescents 8 to 17 Years of Age With Non Alcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 pediatric trial of Elafibranor in children 8-17 with nonalcoholic steatohepatitis was terminated; results posted but details not pro…
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CLINICAL_TRIALS trial_result · 2021-10-11Clinical Trial Update: Tolerability, Efficacy, and PK of ZSP1601 in Patients With Non-Alcoholic Steatohepatitis (NASH) [Phase 1, Phase 2]
Phase 1/2 clinical trial assessing tolerability, efficacy, and pharmacokinetics of ZSP1601 in non-alcoholic steatohepatitis (NASH) has compl…
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CLINICAL_TRIALS trial_result · 2021-09-27Clinical Trial Update: A Phase 2 Study of Elobixibat in Adults With NAFLD or NASH [Phase 2]
A Phase 2 trial of elobixibat in adults with nonalcoholic fatty liver disease or nonalcoholic steatohepatitis has completed, with results po…
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CLINICAL_TRIALS trial_result · 2021-09-23Clinical Trial Update: A Pilot Study to Assess the Safety of Oral Insulin in Patients With Nonalcolholic Steatohepatitis (NASH) [Phase 2]
Phase 2 pilot study evaluating the safety of oral insulin in patients with nonalcoholic steatohepatitis (NASH) and type 2 diabetes; study co…
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CLINICAL_TRIALS trial_result · 2021-09-16Clinical Trial Update: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects With Non-Alcoholic Steatohepatitis [Phase 2]
Phase 2 study evaluating safety, tolerability, pharmacokinetics, and efficacy of EDP-305 in non-alcoholic steatohepatitis has completed with…
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CLINICAL_TRIALS trial_result · 2021-07-29Clinical Trial Update: Study of Safety and Efficacy of Tropifexor (LJN452) in Patients With Non-alcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 trial of Tropifexor (LJN452) in non-alcoholic steatohepatitis was terminated; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-07-14Clinical Trial Update: A Clinical Trial to Evaluate the Efficacy and Safety of Two Aramchol Doses Versus Placebo in Patients With NASH [Phase 2]
Phase 2 trial evaluating two doses of Aramchol versus placebo in non-alcoholic steatohepatitis (NASH) completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-04-21Clinical Trial Update: Investigation of Efficacy and Safety of Three Dose Levels of Subcutaneous Semaglutide Once Daily Versus Placebo in Subjects With Non-alcoholic Steatohepatitis. [Phase 2]
Phase 2 trial evaluating three dose levels of subcutaneous semaglutide once daily vs placebo in non-alcoholic steatohepatitis; study complet…
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CLINICAL_TRIALS trial_result · 2021-04-12Clinical Trial Update: Phase 2b Study in NASH to Assess IVA337 [Phase 2]
Phase 2b study in NASH (IVA337) has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-03-24Clinical Trial Update: A Study of Siliphos in Adults With Non-alcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 clinical trial of Siliphos in adults with fatty liver (NASH) completed; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-01-26Clinical Trial Update: An Investigator Initiated Prospective, Four Arms Randomized Comparative Study of Efficacy and Safety of Saroglitazar, Vitamin E and Life Style Modification in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)/ Non-alcoholic Steatohepatitis (NASH) [Phase 3]
Investigator-initiated Phase 3 randomized trial comparing saroglitazar, vitamin E, and lifestyle modification for NAFLD/NASH.
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CLINICAL_TRIALS trial_result · 2021-01-06Clinical Trial Update: Effect of LIK066 on Reduction of Fatty Content in Livers of Obese Patients [Phase 2]
Phase 2 trial assessing LIK066 for reducing fatty content in livers of obese patients with non-alcoholic steatohepatitis (NASH); study compl…
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CLINICAL_TRIALS trial_result · 2020-10-09Clinical Trial Update: To Evaluate the Effect of Nesinaact on Non-alcoholic Steatohepatitis Through MRI and Liver Fibroscan in Patients With Type 2 Diabetes [Phase 4]
A Phase 4 clinical trial evaluating the effect of Nesinaact on non-alcoholic steatohepatitis in patients with type 2 diabetes using MRI and …
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CLINICAL_TRIALS trial_result · 2020-09-03Clinical Trial Update: Efficacy and Safety of Montelukast in Non Alcoholic Steatohepatitis (NASH) [Phase 4]
Phase 4 trial evaluating efficacy and safety of montelukast in non-alcoholic steatohepatitis has completed.
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CLINICAL_TRIALS trial_result · 2020-08-21Clinical Trial Update: A Study to Evaluate the Safety, Tolerability & Efficacy of MSDC-0602K in Patients With NASH [Phase 2]
Phase 2 study assessing safety, tolerability, and efficacy of MSDC-0602K in patients with non-alcoholic fatty liver disease and non-alcoholi…
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CLINICAL_TRIALS trial_result · 2020-03-17Clinical Trial Update: A Study of the Efficacy and Safety of CF102 in the Treatment of Non-Alcoholic Fatty Liver Disease [Phase 2]
Phase 2 study evaluating CF102 for non-alcoholic steatohepatitis (NASH) has completed.
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CLINICAL_TRIALS trial_result · 2020-03-13Clinical Trial Update: 2-Week Study In People With Nonalcoholic Fatty Liver Disease [Phase 1]
A Phase 1 clinical trial update for a two-week study in adults with nonalcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatit…