Non-alcoholic Steatohepatitis
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH) [Phase 3]
Phase 3 clinical trial update evaluating semaglutide for non-alcoholic steatohepatitis (NASH); the study is currently active but not recruit…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: A Study to Test Whether Survodutide Helps People Living With Obesity or Overweight and With a Confirmed or Presumed Liver Disease Called Non-alcoholic Steatohepatitis (NASH) to Reduce Liver Fat and to Lose Weight (SYNCHRONIZE-MASLD) [Phase 3]
Phase 3 clinical trial completion evaluating Survodutide for obesity with non-alcoholic steatohepatitis (NASH) to reduce liver fat and promo…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Study of Oral Idebenone to Treat Non-Alcoholic Steatohepatitis [Phase 1, Phase 2]
A Phase 1/2 trial of oral idebenone for non-alcoholic steatohepatitis with fibrosis has completed and posted results.
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics of ACT500 in Healthy Adult Participants [Phase 1]
Phase 1 study evaluating ACT500 in healthy adult participants, reporting safety, tolerability, and pharmacokinetics in the context of non-al…
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: To Evaluate the Efficacy and Safety of HSK31679 in Chinese Patients With Non-Alcoholic Steatohepatitis (NASH) . [Phase 2]
A Phase 2 clinical trial update reports completion of the study evaluating HSK31679 for efficacy and safety in Chinese patients with non-alc…
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Pediatric Liver Fat Quantification (LFQ) Phase 2 Pilot Study [NA]
A Phase 2 pediatric pilot trial evaluating liver fat quantification (LFQ) has completed. Results have been posted.
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Ultrasound-Based Liver Fat Quantification (LFQ) Pilot Study [NA]
A completed pilot trial evaluating ultrasound-based liver fat quantification for non-alcoholic fatty liver disease and non-alcoholic steatoh…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Phase 2 Study of MGL-3196 in Patients With Non-Alcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 study of MGL-3196 (resmetirom) in non-alcoholic steatohepatitis has completed, with results posted on 2025-12-23.
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Diagnostic Accuracy of the "LLIFT", a Novel Non-invasive Biomarker for the Diagnosis of Non Alcoholic Fatty Liver (NAFL) and SteatoHepatitis (NASH) in a Population With High Risk of Metabolic Syndrome"
This completed trial assesses the diagnostic accuracy of LLIFT, a novel non-invasive biomarker, for diagnosing non-alcoholic fatty liver dis…
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: Exploratory Study to Assess the Short Term Effect on Liver Enzymes and the Safety of TRO19622 in Patients With Non-Alcoholic Steatohepatitis (NASH) [Phase 2]
This ClinicalTrials.gov update describes a Phase 2 exploratory trial evaluating the short-term effect on liver enzymes and the safety of TRO…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Investigate Safety, Tolerability, PK/PD of J2H-1702 in Healthy Females [Phase 1]
Phase 1 study completed evaluating safety, tolerability, and pharmacokinetics/pharmacodynamics of J2H-1702 in healthy female volunteers, wit…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Investigate Safety, Tolerability, PK/PK of J2H 1702 in Healthy Males [Phase 1]
This document reports the completion of a Phase 1 trial evaluating the safety, tolerability, and pharmacokinetics of J2H 1702 in healthy mal…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Phase 2a Study to Evaluate Safety and Explore Efficacy of J2H-1702 for NASH [Phase 2]
Phase 2a trial evaluating the safety and preliminary efficacy of J2H-1702 in non-alcoholic steatohepatitis has completed.
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: A Study to Assess the Safety and Tolerability of Single Doses of AZD4076 in Healthy Male Subjects [Phase 1]
A Phase 1 study evaluating the safety and tolerability of single doses of AZD4076 in healthy male subjects has completed.
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Research Study on Whether a Combination of 2 Medicines (NNC0194 0499 and Semaglutide) Works in People With Non-alcoholic Steatohepatitis (NASH) [Phase 2]
A Phase 2 clinical trial evaluating the combination of NNC0194 0499 and semaglutide for non-alcoholic steatohepatitis has completed.
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Screening of Liver Fibrosis Using Blood Tests in Patients With Type 2 Diabetes Mellitus [NA]
This completed clinical trial evaluated blood-test screening for liver fibrosis in people with Type 2 diabetes mellitus. The study included …
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: A Study of Efinopegdutide in Participants With Hepatic Impairment (MK-6024-014) [Phase 1]
Phase 1 trial evaluating Efinopegdutide in participants with hepatic impairment and non-alcoholic steatohepatitis has completed and results …
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Study of ARO-HSD in Healthy Volunteers and Patients With Non-Alcoholic Steatohepatitis (NASH) or Suspected NASH [Phase 1, Phase 2]
Clinical trial update reports Phase 1 and Phase 2 results for ARO-HSD in healthy volunteers and patients with non-alcoholic steatohepatitis …
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: French Cohort for the Study of Non-invasive Tests of Liver Lesions in NAFLD/NASH (FreSH Cohort) [NA]
The FreSH Cohort study in France, evaluating non-invasive tests for liver lesions in non-alcoholic fatty liver disease (NAFLD/NASH), has com…
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: Effect of Adjustable Intragastric Balloon in Obese Non-alcoholic Fatty Liver Disease [NA]
A completed clinical trial assessing the effect of an adjustable intragastric balloon in obese individuals with non-alcoholic fatty liver di…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: A Randomised, Open-Label Study to Evaluate the Relative and Absolute Bioavailability of Cotadutide in Healthy Subjects [Phase 1]
Phase 1 open-label trial to evaluate the relative and absolute bioavailability of Cotadutide in healthy subjects, sponsored by AstraZeneca.
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: A Study to Test Whether BI 685509 Alone or in Combination With Empagliflozin Helps People With Liver Cirrhosis Caused by Viral Hepatitis or Non-alcoholic Steatohepatitis (NASH) Who Have High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver) [Phase 2]
A Phase 2 study evaluating BI 685509 alone or with empagliflozin for liver cirrhosis due to viral hepatitis or non-alcoholic steatohepatitis…
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Study to Evaluate the Effects of Hepatic Impairment on the Pharmacokinetics of Miricorilant [Phase 1]
A Phase 1 study evaluated how hepatic impairment affects the pharmacokinetics of miricorilant in Non-alcoholic Steatohepatitis (NASH). The t…
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CLINICAL_TRIALS trial_result · 2025-02-18Clinical Trial Update: A Research Study Looking at How the Compound NNC0194-0499 Works With Birth Control Pills in Women Not Able to Bear Children. [Phase 1]
Phase 1 clinical trial evaluating the interaction between the investigational compound NNC0194-0499 and birth control pills; the study has c…
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CLINICAL_TRIALS trial_result · 2025-02-06Clinical Trial Update: Clinical Effects of New Approach on Patients With Non-alcoholic Steatohepatitis [EARLY_Phase 1]
This update summarizes the results of an early-phase Phase 1 clinical trial evaluating a new approach for patients with non-alcoholic steato…