Neuromyelitis Optica
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CLINICAL_TRIALS trial_result · 2018-05-02Clinical Trial Update: Autologous Hematopoietic Stem Cell Transplant in Neuromyelitis Optica [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating autologous hematopoietic stem cell transplant in Neuromyelitis Optica has been terminated.
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Safety and Efficacy of Sustained Release Dalfampridine in Transverse Myelitis (Re-Launch) [Phase 2]
A Phase 2 clinical trial evaluating sustained-release dalfampridine for transverse myelitis and related conditions has completed, with resul…
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CLINICAL_TRIALS trial_result · 2016-07-20Clinical Trial Update: A Multicentre randomiSed Controlled TRial of IntraVEnous Immunoglobulin Versus Standard Therapy for Transverse Myelitis [Phase 3]
A Phase 3 multicenter randomized trial comparing intravenous immunoglobulin to standard therapy for transverse myelitis has been terminated.
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CLINICAL_TRIALS trial_result · 2015-05-29Clinical Trial Update: Efficacy of Bevacizumab (Avastin) in Treatment of Acute NMO Exacerbations [Phase 1]
Phase 1 study evaluating bevacizumab for acute neuromyelitis optica exacerbations; the trial completed and posted results in 2015.
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CLINICAL_TRIALS trial_result · 2014-07-18Clinical Trial Update: C1-esterase Inhibitor (Cinryze) for Acute Treatment of Neuromyelitis Optica Exacerbation [Phase 1]
Phase 1 trial evaluating Cinryze (C1-esterase inhibitor) for acute treatment of an exacerbation in neuromyelitis optica. The study completed…
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EMA guidance · 2014-07-10Registration opens for workshop on clinical trial design in neuromyelitis optica to facilitate global medicine development in a rare and serious disease
EMA announces registration open for a workshop focused on designing clinical trials for neuromyelitis optica to support global development i…
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CLINICAL_TRIALS trial_result · 2013-12-27Clinical Trial Update: Efficacy and Safety of Mitoxantrone in Patients With Refractory Neuromyelitis Optica and Spectrum Disorders [Phase 4]
Phase 4 trial evaluating the efficacy and safety of mitoxantrone in patients with refractory neuromyelitis optica and related disorders.
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CLINICAL_TRIALS trial_result · 2013-11-04Clinical Trial Update: An Open Label Study of the Effects of Eculizumab in Neuromyelitis Optica [Phase 1, Phase 2]
An open-label Phase 1/2 trial evaluating eculizumab in neuromyelitis optica (Devic's disease) has completed, with results posted in 2013.
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CLINICAL_TRIALS research · 2012-11-28Clinical Trial Update: Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Progressive Multiple Sclerosis and Neuromyelitis Optica [Phase 1, Phase 2]
This clinical trial update reports on the safety and efficacy evaluation of Umbilical Cord Mesenchymal Stem Cell Therapy for patients with P…
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CLINICAL_TRIALS trial_result · 2011-09-27Clinical Trial Update: Safety and Tolerability of Rituximab in Neuromyelitis Optica [Phase 1]
Phase 1 trial evaluating the safety and tolerability of rituximab in patients with Neuromyelitis Optica has been completed.
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CLINICAL_TRIALS research · 2010-06-28Clinical Trial Update: Evaluation of Neural Loss in Multiple Sclerosis and Neuromyelitis Optica Using High Resolution Oct
A clinical trial update describing a study evaluating neural loss in multiple sclerosis and neuromyelitis optica using high-resolution optic…